Frequency Therapeutics — Hearing Loss Regeneration

[Reinier]

colleges

Sorry. Supposed to be colleagues

but you'd likely ask them to not tell others

It would still surprise me if this can be kept quit. No pun intended.
Perhaps we will know soon

 

[Don Tinny]

It's bullshit. They said they would let us know in December. It's now December. Some of us are hanging on a thread... each day is a day closer to giving up... I have emailed Frequency Therapeutics hundreds of times with no response. I also emailed FDA, no respomse. Nothing nothing. They just don't care

Here some users have said that the results will be published in a few months.

 

[JohnAdams]

It's bullshit. They said they would let us know in December. It's now December. Some of us are hanging on a thread... each day is a day closer to giving up... I have emailed Frequency Therapeutics hundreds of times with no response. I also emailed FDA, no respomse. Nothing nothing. They just don't care

Yeah. Emailing them hundreds of times is only going to get you on an email block list. Trust me I am right there with you, I think everything is moving far too slow. Just hold on. We have no idea what the near future holds.

 

[Philip83]

Sorry if this has been discussed already but has there been any official statements mentioning tinnitus and the potential impact FX-322 might have on it by Frequency Therapeutics? Like in any lectures or interviews or Q&A, etc?

 

[Deathtotinni]

But you can enter this forum anonymously and I guess nobody will discover you.

Of course those who are "healed" may want to continue with their lives without looking back.

I think they are healed and no longer think about it.

Where are you getting this from? Is this directly from Frequency Therapeutics? I would have thought it would be the opposite. People with tinnitus and hyperacusis have much more to gain and need this much more than people who just have hearing loss.

I'm gonna try to get into the next stage of FT's trials. Do you think I should not mention my tinnitus or hyperacusis?

My hearing loss bothers me more now than my tinnitus does. Struggling to hear little things and being in loud places with some many tones can bother me unless I plug that ear.

 

[Deathtotinni]

Sorry if this has been discussed already but has there been any official statements mentioning tinnitus and the potential impact FX-322 might have on it by Frequency Therapeutics? Like in any lectures or interviews or Q&A, etc?

No, in January they will release a statement about the data.

 

[Deathtotinni]

It's bullshit. They said they would let us know in December. It's now December. Some of us are hanging on a thread... each day is a day closer to giving up... I have emailed Frequency Therapeutics hundreds of times with no response. I also emailed FDA, no respomse. Nothing nothing. They just don't care

I think a hearing aid would help but they aren't all that cheap. All my doctors have said a hearing aid will help with tinnitus.

 

[Deathtotinni]

Sorry. Supposed to be colleagues

It would still surprise me if this can be kept quit. No pun intended.
Perhaps we will know soon

Next month we will know.

 

[d'Wooluf]

Sorry if this has been discussed already but has there been any official statements mentioning tinnitus and the potential impact FX-322 might have on it by Frequency Therapeutics? Like in any lectures or interviews or Q&A, etc?

No. I think I've seen them all and it's never been mentioned. There was a discussion on Reddit where one of the participants who is believed to be Will McLean from Frequency Therapeutics said that he believed that reversing hearing loss might help with tinnitus. He likened tinnitus to phantom sensations from an amputated limb. This was his personal opinion in response to someone's question, not an official statement.

 

[rid0871]

I got hearing aids which cost close to $9000. They do nothing to the high-pitched noise. I can't take this much longer. Frequency Therapeutics said they would let us know in December. They should keep their word. If it's not effective, then I'm DONE. I can't do it anymore.

 

[Street Novelist]

I was told they would publish the results in December. Where are people getting the January answer?

 

[john paul]

I think everyone is forgetting that FX-322 is not aiming at curing tinnitus, it's aiming to restore hearing.

It's still only a theory that it will help tinnitus as a secondary result.

Hence they don't even talk about tinnitus.

 

[Philip83]

I think everyone is forgetting that FX-322 is not aiming at curing tinnitus, it's aiming to restore hearing.

It's still only a theory that it will help tinnitus as a secondary result.

Hence they don't even talk about tinnitus.

Since the aim is to first and foremost target hearing loss caused by noise trauma, I think the chances are fairly substantial that tinnitus caused by noise trauma will in some way be affected by the treatment if it is successful. I think a reduction in actual tinnitus volume would certainly be plausible.

Did some YouTube-scanning on Frequency Therapeutics, and I'm sure the video has been posted here before, but man does a slide like this make me hopeful. Look at that shit! That's not some half-ass try of a reconstruction - that's almost perfection! Ex vivo, yes, but still.

 

[JohnAdams]

Sorry if this has been discussed already but has there been any official statements mentioning tinnitus and the potential impact FX-322 might have on it by Frequency Therapeutics? Like in any lectures or interviews or Q&A, etc?

Not official. But it is believed that a Reddit user named "TheLeviathan" is Will McLean from Frequency Therapeutics. This person at least claimed to work in the lab that developed this technology. In a Reddit post he stated that he strongly believed that tinnitus is from hearing loss and it would alleviate tinnitus. Just search around for it, it's been posted here several times. Also read the Reddit thread. He basically gets attacked for even mentioning this hypothesis.

 

[JohnAdams]

I was told they would publish the results in December. Where are people getting the January answer?

The Bloomberg interview with Frequency Therapeutics CEO David Lucchino.

 

[Philip83]

Not official. But it is believed that a Reddit user named "TheLeviathan" is Will McLean from Frequency Therapeutics. This person at least claimed to work in the lab that developed this technology. In a Reddit post he stated that he strongly believed that tinnitus is from hearing loss and it would alleviate tinnitus. Just search around for it, it's been posted here several times. Also read the Reddit thread. He basically gets attacked for even mentioning this hypothesis.

Cool, thanks.

 

[Don Tinny]

I think everyone is forgetting that FX-322 is not aiming at curing tinnitus, it's aiming to restore hearing.

It's still only a theory that it will help tinnitus as a secondary result.

Hence they don't even talk about tinnitus.

I'm 99% sure that your tinnitus will disappear, or at least it will become almost inaudible, the day you restore your hearing.

My tinnitus changes as the days go by, it fluctuates. Today, for example, I'm having a pretty good and moderate day. It is not a permanent and constant thing. But it's just my opinion...

 

[john paul]

@Philip83 IMO they already have this in the bag, it's just a waiting game now.

 

[JohnAdams]

What if the reason that the cochlea doesn't heal on its own is because mammalian endolymph is devoid of healing factors and transport mechanisms required for healing that are in fact present in human blood?

 

[Reinier]

Next month we will know.

Difficult to rein in enthusiasm. But I am not Data or Spock from Star-Trek
Also I am reluctant to put all eggs in one basket.

 

[RB2014]

I got hearing aids which cost close to $9000. They do nothing to the high-pitched noise. I can't take this much longer. Frequency Therapeutics said they would let us know in December. They should keep their word. If it's not effective, then I'm DONE. I can't do it anymore.

There is really good evidence it will help with tinnitus. Hang in there.

 

[Enclave]

I got hearing aids which cost close to $9000. They do nothing to the high-pitched noise. I can't take this much longer. Frequency Therapeutics said they would let us know in December. They should keep their word. If it's not effective, then I'm DONE. I can't do it anymore.

Hang in there. 2019 is going to be the Year of the Ear. A lot of movement will come to fruition this coming calendar year. Keep your head up.

 

[john paul]

I'm 99% sure that your tinnitus will disappear, or at least it will become almost inaudible, the day you restore your hearing.

My tinnitus changes as the days go by, it fluctuates. Today, for example, I'm having a pretty good and moderate day. It is not a permanent and constant thing. But it's just my opinion...

Same, mine is constantly changing. Some nights I can sit there in a silent room in the dead of night and be pretty much in perceived silence. Other times I need to mask it or my head would pop. Very strange, but I figure that sleep, stress and general well being play the biggest part. It seems every day our bodies and brain are in a different state, it's just normal people don't have anything to gauge it on and we do.

 

[Don Tinny]

Same, mine is constantly changing. Some nights I can sit there in a silent room in the dead of night and be pretty much in perceived silence. Other times I need to mask it or my head would pop. Very strange, but I figure that sleep, stress and general well being play the biggest part. It seems every day our bodies and brain are in a different state, it's just normal people don't have anything to gauge it on and we do.

Yes. It's some weird brain thing! But I think hearing loss is "food" for this crap.

 

[Tonny]

I think restoring hearing might help a lot of us, but not everybody. Tinnitus is a complex beast, but for me I think it will help. Restoring the dead cells to send signals again adjusting the threshold.

However, if it's just to grow new cells is a good question since I hear that they should grow in some structural way to fully function. But I can take a bit distorted hearing as long as the tinnitus is going down a bit.

 

[Reinier]

But I can take a bit distorted hearing as long as the tinnitus is going down a bit.

Don't underestimate distorted hearing. I have both distorted hearing and tinnitus. My tinnitus is pretty tiresome, but I hate the distorted hearing even more.
What does not help at all is that I used to appreciate good quality sound systems.

 

[JohnAdams]

Well, we are nearing the end of this phase 1/2 trial for hearing loss restoration.

There is a good chance that tinnitus has been cured, maybe, maybe not.

I'd really like to know soon.

 

[JohnAdams]

How can the people at Tinnitus Hub, the ATA and the BTA not be talking about this?

This is potentially far more profound than MuteButton.

What's the excuse again?

 

[incelitus]

Do hair cells matter when it comes to balance or is that just the vestibulocochlear nerve?

I assume if your nerve is fucked there's not much point in getting the hair cells fixed?

I'm confused.

 

[JohnAdams]

Do hair cells matter when it comes to balance or is that just the vestibulocochlear nerve?

I assume if your nerve is fucked there's not much point in getting the hair cells fixed?

I'm confused.

Yeah hair cells are in the vestibular thingy.
I may be wrong but I think getting the drugs into that part of the ear is much more difficult than the cochlea.