Do you think you could give me a brief summary of what happens if we don't have enough acetycholine?
It's a pretty broad topic, but I'll mention a few things as to how I think it relates to tinnitus, and some of the things many of us experience as a result of tinnitus. Perhaps first to know, is that we couldn't move any muscle(s) in our body without acetylcholine. So it makes sense that if you disrupt the natural workings of acetylcholine with inhibiting drugs, you'll get some kind of reaction from muscles. In most cases, and in most people, it will relax them. But for others, it causes the opposite effect, which can bring on muscle twitching and excitability.
When I see how so many people with tinnitus get anxious, and have all kinds of things going on in their ears such as twitching, and pain syndromes, etc., I can't help but think their acetylcholine levels may be low. I've noticed that some people w/ tinnitus have benefitted from taking some kind of choline supplement--such as phosphytidal choline--or eating foods high in choline, such as egg yolks. I've noticed that if I eat an abundance of egg yolks, it has a calming, almost sedative effect on me. --
@ruben ruiz @humptydumpty69
Acetylcholine is also critical for forming memories. Anticholinergic drugs can easily cause a number of memory problems, including Alzheimer's and dementia. Many people, especially the elderly, are often prescribed several anticholinergic drugs, and almost unbelievably, they're only just now beginning to document the direct correlation between dementia and the number of these drugs taken. -- I sometimes wonder if the reason some people with tinnitus can't concentrate is because--in addition to the "distracting" tinnitus--their acetylcholine levels may be on the low side.
I recently read a story of a woman who was given an anticholinergic "patch" to wear on her arm before she want on a cruise ship, to prevent nausea. When she got back after three weeks, her excellent memory had deteriorated badly, and four years later had not improved. -- Here's a link to an article that gives a pretty good overview...
Discovery and Functions of Acetylcholine