Has Anyone on Here Used Glycine for Sleep and/or Anxiety?

JasonP

Member
Author
Dec 17, 2015
1,762
Tinnitus Since
6/2006
So I am looking for an alternative to klonopin for calming. Melatonin used to be working great but for some reason lately, not as good. (Could be because of other stuff I am taking or some other reasons).

I read some reviews on Amazon where people were taking glycine for sleep and anxiety and was curious to know if anyone on here took it and if it affected their tinnitus.
 
In Russia glycine is used by everyone - from babies to elders - it is absolutely harmless (placebo-kind of stuff :)). Popular among students to raise focus and calm down nerves before exams.
You can try, but I wouldn't have high hopes
 
In Russia glycine is used by everyone - from babies to elders - it is absolutely harmless (placebo-kind of stuff :)). Popular among students to raise focus and calm down nerves before exams.
You can try, but I wouldn't have high hopes
Thanks! I may try it. What dosage is best?
 
Interesting. I have never tried. 3g an hour before bed seems to be the recommended dose. It's an amino acid found in food, so not likely to be harmful at a low dose. Let us know how you get on if you try it. I could certainly do with a sleep aid that is non-pharmaceutical.
 
Interesting. I have never tried. 3g an hour before bed seems to be the recommended dose. It's an amino acid found in food, so not likely to be harmful at a low dose. Let us know how you get on if you try it. I could certainly do with a sleep aid that is non-pharmaceutical.

Thanks for finding that out. The only thing I am concerned about is tinnitus increasing so I need to think about it more. According to Amazon, there were plenty of reviews where it said it relaxed people and helped them sleep. It is interesting what receptors in the brain it works on. Right now, I am experimenting with something else but might try it sometime in the future.

If anyone else tries this, please comment here so we can know how it may effect people with tinnitus.
 
Thanks! I may try it. What dosage is best?

It usually comes in 100 mg pill (in Russia). You take it for 30 days if you want to ease stress (3 times a day) and you can repeat the course with 30-days break, or you place in under your tongue 20 min before you go to sleep if you want to fix your sleeping pattern. You can have up to 6 courses per year.
You're welcome :)
 
I actually got some and tried last night. Didn't help me sleep. Ended up taking half a sleeping tablet. Tinnitus rubbish today
 
I actually got some and tried last night. Didn't help me sleep. Ended up taking half a sleeping tablet. Tinnitus rubbish today

I am so sorry. I hate that you spent all that money and it did not work. Can I ask how much you took and if it affected your tinnitus?
 
I've used glycine in the past. Carlson has a jar of loose powder that you measure out with a small scoop. It's okay stuff but not a miracle cure by any means. It made me tired but didn't help my sleep much. I neither hated nor loved it. (Conversely melatonin makes me feel sick and groggy. I hate that stuff.)

One possibly good thing about glycine is that it's available in combination with magnesium, which definitely helps with anxiety and sleep (at least for me). You can try magnesium glycinate as a pill and see how it helps you. Personally I love magnesium and find it is a great "relaxer". Plus it's all natural, not addictive and cheap. I will mention that I'm not a huge fan of magnesium glycinate personally because it tends to constipate me. Magnesium by itself is a natural laxative in high doses but when it's combined with glycine, an amino acid, it has the opposite affect for me. So I prefer to use other types of magnesium supplementation these days. Some people love the stuff though so I guess it's personal preference.

If your goal is to calm anxiety via natural supplementation I would suggest you explore magnesium in more detail. It is available in countless varieties (oxide, citrate, glycinate, taurate, aspartate, chloride, etc.). It's also fairly cheap. Lately I've been using magnesium oxide and have been sleeping like a rock, plus I'm very calm during the day. Handling my tinnitus is much easier when I'm calm.

Good luck
 
I am so sorry. I hate that you spent all that money and it did not work. Can I ask how much you took and if it affected your tinnitus?
I don't think if affected my tinnitus but then it is so loud these days that I don't think much could increase it. Pharmacologically there is more reason to believe it would worsen tinnitus as glycine acts as a neurotransmitter which is inhibitory rather than excitatory. I was told at health shop that you should start low and increase so I started with one capsule of 0.5gram. I may need to increase but doubt on it's own it will help as I have very bad insomnia and nothing non-prescription has helped as yet. I am always looking to improve my sleep as insmonia makes you feel horrible.
 
I've used glycine in the past. Carlson has a jar of loose powder that you measure out with a small scoop. It's okay stuff but not a miracle cure by any means. It made me tired but didn't help my sleep much. I neither hated nor loved it. (Conversely melatonin makes me feel sick and groggy. I hate that stuff.)

One possibly good thing about glycine is that it's available in combination with magnesium, which definitely helps with anxiety and sleep (at least for me). You can try magnesium glycinate as a pill and see how it helps you. Personally I love magnesium and find it is a great "relaxer". Plus it's all natural, not addictive and cheap. I will mention that I'm not a huge fan of magnesium glycinate personally because it tends to constipate me. Magnesium by itself is a natural laxative in high doses but when it's combined with glycine, an amino acid, it has the opposite affect for me. So I prefer to use other types of magnesium supplementation these days. Some people love the stuff though so I guess it's personal preference.

If your goal is to calm anxiety via natural supplementation I would suggest you explore magnesium in more detail. It is available in countless varieties (oxide, citrate, glycinate, taurate, aspartate, chloride, etc.). It's also fairly cheap. Lately I've been using magnesium oxide and have been sleeping like a rock, plus I'm very calm during the day. Handling my tinnitus is much easier when I'm calm.

Good luck

If I take 200mg magnesium glycinate, how much glycine is in there? It does calm me down. My goal is to stay asleep for 8 hours without waking up. Haven't done that in a long time. I might could if I took a whole lot of klonopin which I don't want to do.
 
If I take 200mg magnesium glycinate, how much glycine is in there? It does calm me down. My goal is to stay asleep for 8 hours without waking up. Haven't done that in a long time. I might could if I took a whole lot of klonopin which I don't want to do.

I can't say for certain as every supplement differs when it comes to ingredients, fillers, binders, etc. I did find a link that says you should have about 617 mgs of glycine (or more) with 200 mg Mag. The link explains it better:

http://chemistry.stackexchange.com/questions/47324/glycine-in-magnesium-glycinate
 
Anyone here that takes Glycine together with an antidepressant? I saw by searching on Google that it interacts with Serotonin so I wonder if it's safe to use if you are under an antidepressant, especially if you have SSRI induced tinnitus.
 

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