I find it highly odd that we have multiple companies suddenly chasing the same therapy with very similar methods.
Most likely because our biological understanding of the inner ear has grown tremendously the last decade.
They haven't said anything at all. That's just my estimate as they appear to be moving very fast on their own.
I'm simply not optimistic at all. Why would I be? These drugs are not on the market now, and they may never make it that far. Only when they are on the market will I show some optimism. Even then it is a big unknown if they will help anyone.
If I could go back in time I would have taken CBT over going on Prozac, which has led to me getting tinnitus.
We don't necessarily need imagining technology although that would be very helpful. All the study would need to do is apply the compound to one ear only, wait for said individual to die, and then dissect that person. If there is a big difference between the nerve connections from the treated ear versus the non-treated ear you can infer the injection had an impact.
If they offer my wife and children enough money to last them a life time I may be that volunteer.We don't necessarily need imagining technology although that would be very helpful. All the study would need to do is apply the compound to one ear only, wait for said individual to die, and then dissect that person. If there is a big difference between the nerve connections from the treated ear versus the non-treated ear you can infer the injection had an impact.
Who wants to volunteer??
That's what CBT is really for, depression, anxiety, phobias etc. Not distress from actual physical diseases.
Yep. People don't see tinnitus as something real. Hell, my wife thinks it is a figment of my imagination. She says lift the depression and it will disappear. Err no!! Lift the depression and I'll still be left with tinnitus, but the depression isn't going anyway because of the tinnitus. If that all made sense.
It does, it's a vicious cycle. You can try to get used to the sound (you don't have to take CBT to try). I've been trying to do that with my nearly unmaskable ringing and I'm slowly getting there. I sure as hell still hate it though.
Well it's a good thing you're on this forum regarding a drug that's in the works, shitting on it for the rest of us hopefuls.
Same here. I was the polar opposite more often than not.
Also, even if these drugs do hit the market, I reckon they will not suddenly become widely available due to cost and other reasons. And as first generation drugs they will probably be riddled with side effects.
Why not? It would be great if they aren't. I've had my life screwed up enough by side effects already.
Well for one, this pill has already been shown to be safe, and the other stuff being tested for tinnitus/hearing loss haven't shown any adverse effects that I'm aware of.
Exactly, and if people are worried then they don't have to buy it. All of the drugs doctors give you mess up enzymes, BP levels etc. If it passed the safety trials release it, but don't take 4 years and all the funds to say sorry it didn't work. It may not work in three days when you take it or for years when these trials get through.
When is a drug considered safe? I mean, most drugs have lists of side effects attached to them and are considered safe. I wonder what the criteria is?
But all drugs have side effects, drugs for Rheumatoid Arthritis can actually cause cancer.
I just meant in general to be considered safe and proceed to phase 2. A drug can be considered "safe" if it had minor side effects.
BDNF isn't a drug. It is a biological compound that is already present in your body.
Member
