MemberWhich article are you referring to which talks about the patient having tinnitus and hyperacusis while receiving this treatment? Does it mention their hyperacusis and tinnitus going away after they had the treatment?
Hough Ear Institute's Hair Cell Regeneration Project
- Thread starter all to gain
- Start date
- Mar 6, 2017
- 778
- Tinnitus Since
- 12/2016
- Cause of Tinnitus
- Shooting/loud noise
ColinUK
Member
- Sep 13, 2020
- 87
- Tinnitus Since
- 2013 initial, worsened 2020
- Cause of Tinnitus
- Initial Music Gig, Worsened Cinema or possible covid
Just don't get what's happened here? Hough Ear Institute took donations of people to develop hearing loss treatments, now that's shelved and it's a cancer drug?? Or are they still developing it as a hearing loss / tinnitus treatment?
- Mar 6, 2017
- 778
- Tinnitus Since
- 12/2016
- Cause of Tinnitus
- Shooting/loud noise
Hough Ear Institute did say there would be a two year study until 2022. If nothing starts by then or 2023, they are definitely bullshitting.
DimLeb
Member
- Jun 20, 2021
- 358
- Tinnitus Since
- 03/2021
- Cause of Tinnitus
- Idiopathic Cochleopathy or Maybe Loud Music
It was already scammy enough that they were gathering donations for a non-existent reason, and now it looks like they gave the drug away. That's really bad. I want my 50 euros back lol.
The amount of involvement the US Government has with this drug makes it being a scam a bad idea. Especially with Hough Ear Institute receiving money from both the DoD and the State Government of Oklahoma. There is the potential that the drug might not help those with long-term tinnitus. There is evidence with animal testing that implies the drug can aid with long-term tinnitus. Keep in mind that what works for animals like rodents may not work for humans. Though it is a much smaller leap than quail to humans like studies from the 80s observed.
Right now it is too soon to tell that this drug will be the cure nerve damage tinnitus sufferers have been waiting for. There is a lot of research out there and keeping a hopeful outlook has more fruitful potential than blanket skepticism.
Right now it is too soon to tell that this drug will be the cure nerve damage tinnitus sufferers have been waiting for. There is a lot of research out there and keeping a hopeful outlook has more fruitful potential than blanket skepticism.
I'd argue the opposite, actually. Putting your hope in something which has a high chance of failure puts you up for disappointment. Keep that hope for Otonomy or Susan Shore's device.
- Nov 29, 2014
- 211
- Tinnitus Since
- 10/2007
- Cause of Tinnitus
- Acoustic trauma - Repeated gun blasts
And then be disappointed with them instead lol. There is nothing but disappointments and suffering in this field unfortunately.
Please don't give up hope my friend. Medical science is making strides every day in understanding the mind. A real solution will manifest in the efforts of numerous groups from across the world.
- Apr 23, 2019
- 364
- Tinnitus Since
- 04/2019
- Cause of Tinnitus
- Slap to the ear / Leading to more issues after ear surgery
You can apply for compassionate use, see attached email:
Hey Scott!
The short answer is yes, our hearing loss pill, NHPN-1010, is available through the FDA's expanded access program and anyone in the US can apply to receive it. You can find information about how to apply here.
Unfortunately, HEI has nothing to do with the application process so I don't know anything about it. I do know you'll need to apply through your physician since it's not a fully approved therapeutic. I also know, you'll need to contact Oblato, Inc. to get samples of NHPN-1010 since they are our licensing partners for this therapeutic and the actual manufacturers.
Best of luck to you! If you would like to know more about our other research endeavors, sign up to receive our newsletter.
ASHLEY EVERETT
Philanthropy Coordinator
AfroSnowman
Member
- Jul 23, 2019
- 1,075
- Tinnitus Since
- 04/2019
- Cause of Tinnitus
- Nonnatural energy source
- Mar 6, 2017
- 778
- Tinnitus Since
- 12/2016
- Cause of Tinnitus
- Shooting/loud noise
Dude, nice! I've been trying to figure this out for months! Good find. So Ashley is from where though?
- Jan 15, 2022
- 58
- Tinnitus Since
- 11/2021
- Cause of Tinnitus
- Loud noise/ Covid? / Benzos / Ototoxicity
I would take it for sure. Any way I could get it living in Spain? You just can't imagine how desperate I am...
- Mar 2, 2018
- 280
- Tinnitus Since
- 2/2018
- Cause of Tinnitus
- Rock 'n Roll
I think Ashley is the new @Justin De Moss - aka Philanthropy Director for Hough Ear Institute. Are we all applying for this or what? Or is this only for acute NIHL?
IntotheBlue03
Member
Any takers on this? I haven't followed this but assuming it's for exclusively noise induced/hearing loss tinnitus?
I spoke with Justin from Hough Ear Institute on the phone a year ago. Their drug candidate was actually indicated for something else, which I forget, maybe seizures? And they had a number of people report in the trial that their hearing and tinnitus had improved, not something anyone was looking for...
So it would seem the drug is safe for humans.
So it would seem the drug is safe for humans.
Keep in mind that this pill is not the OPI-001 (chronic hearing damage/tinnitus), but for acute trauma.
There is absolutely 0 evidence as of yet that this works for tinnitus. It is not even trialed for tinnitus patients! Only a Phase 1 for safety purposes on healthy patients!
There is absolutely 0 evidence as of yet that this works for tinnitus. It is not even trialed for tinnitus patients! Only a Phase 1 for safety purposes on healthy patients!
- Mar 6, 2017
- 778
- Tinnitus Since
- 12/2016
- Cause of Tinnitus
- Shooting/loud noise
I think as many people should apply for it as possible yes. My next doctor's visit I will. I mean why not. If people here have ear problems bad enough, definitely apply for it. We got nothing to lose. It should help either way.
I think it's most interesting for somebody who has hyperacusis, noxacusis, distortions, 6 tinnitus sounds like myself to see what improves.
Study to Determine the Safety, Tolerability, and Pharmacokinetic Profile of HPN-07 and HPN-07 Plus NAC
Phase 1 study was only for healthy individuals. Neither the primary nor secondary outcome was measuring anything related to hearing or tinnitus. Purely safety.
Any improvement were merely anecdotal, not a single piece of research paper anywhere. We know how subjective tinnitus is, placebo effect etc. There were only studies done on lab rats.
Don't get me wrong, very curious to the outcomes of individuals that manage to get their hold on this, but there is more evidence that Magnesium pills have positive impact on tinnitus than this pill...!
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