My Posting Place

no-new-news-from-frequencytx-in-the-last-month-still-checks-their-website-every-30-minutes.jpg
 
wrap your heads around this one.
from the fx 322 patent:
"
The cochlea relies heavily on all present cell types, and the organization of these cells is important to their function. As supporting cells play an important role in neurotransmitter cycling and cochlear mechanics. Thus, maintaining a rosette patterning within the organ of Corti may be important for function. Cochlear mechanics of the basilar membrane activate hair cell transduction. Due to the high sensitivity of cochlear mechanics, it is also desirable to avoid masses of cells. In all, maintaining proper distribution and relation of hair cells and supporting cells along the basilar membrane, even after proliferation, is likely a desired feature for hearing as supporting cell function and proper mechanics is necessary for normal hearing.

In one embodiment of the present disclosure, the cell density of hair cells in a cochlear cell population is expanded in a manner that maintains, or even establishes, the rosette pattern characteristic of cochlear epithelia."

https://patents.google.com/patent/US9968615B2/en

View attachment 21370

Does this mean they have been doing advanced, proprietary research into this? As in things that will make this super badass that they haven't revealed? How do you control the patterning of regrown hair cells?
Do regenerated hair cells end in the correct shape and order within the cochlear spiral or are they disorganized and sloppy? This is something I am worried about, nature isn't perfect there could be many bio complications.
 
Do regenerated hair cells end in the correct shape and order within the cochlear spiral or are they disorganized and sloppy? This is something I am worried about, nature isn't perfect there could be many bio complications.
It could seriously alter the frequency response in unwanted ways. All we can do is hope that it is a magic bullet.
 
It could seriously alter the frequency response in unwanted ways. All we can do is hope that it is a magic bullet.
someone needs to ask Aaron, he's an investor and I think he gets info that the public doesn't.
 
Hello MPP,

I was just wondering what this thread was about. Is it specifically for memes?

Jack
 
Not really. It's technically about whatever but the precedent set is meme-based.

Are the memes centered around a specific theme? (tinnitus, sports, media, tv shows, misc)
 
I wish they would study me. I'm the perfect lab rat. My tinnitus goes all over the place. I almost experienced complete silence today sitting in my coworker's office.

That's the lowest it has been since I've had it.

The only thing I've been doing differently is I've been taking a fish oil goo and also yesterday, I got drunk at about 5:30, then instead of continually drinking until I passed out, I sobered up, drank a bunch of water then went to bed and got 8.5 hours of sleep.
 
Last edited:
@JohnAdams look into also taking Vitamin C, Vitamin E, Vitamin A, Magnesium Citrate, & Zinc Picolinate if you are looking for ear health supplements.

Potentially look into taking NAC too. Unfortunately, I had an adverse reaction to it so I stopped taking it.
 
@JohnAdams look into also taking Vitamin C, Vitamin E, Vitamin A, Magnesium Citrate, & Zinc Picolinate if you are looking for ear health supplements.

Potentially look into taking NAC too. Unfortunately, I had an adverse reaction to it so I stopped taking it.
I take vitamin A (fish oil), ginko, and CBD oil. I was on zinc and NAC and those didnt seem to do anything.
 
I take vitamin A (fish oil), ginko, and CBD oil. I was on zinc and NAC and those didnt seem to do anything.

You learn new things every day! I didn't know vitamin A was fish oil. I feel somewhat embarrassed because it seems so elementary.

You should continue to take Zinc if possible. It is very good for your ears as is help balance out the amount of copper in your body. How much NAC were you take and what effects were you expecting? Does CBD help with tinnitus or are you taking it for other reasons?
 
You learn new things every day! I didn't know vitamin A was fish oil. I feel somewhat embarrassed because it seems so elementary.

You should continue to take Zinc if possible. It is very good for your ears as is help balance out the amount of copper in your body. How much NAC were you take and what effects were you expecting? Does CBD help with tinnitus or are you taking it for other reasons?
They claim cbd oil is a "neuro-protectant" whatever that means. I take it to try and strengthen my nervous system against stress. For me it has absolutely no affect on my tinnitus. It may be helping me sleep better.
 
They claim cbd oil is a "neuro-protectant" whatever that means. I take it to try and strengthen my nervous system against stress. Stress can kill you.

Interesting. So it helps you with everyday stress and anxiousness? Might be worth looking into.
 
Me too, but numbskull ENT says I have perfect hearing. Even if FX works I wonder if these bastard ENTs will let people like us us have it.
If it is reported in the trials that the subjects had tinnitus and it improves, then it will be FDA approved for tinnitus. It expands the market. More $$$$.
 
Me too, but numbskull ENT says I have perfect hearing. Even if FX works I wonder if these bastard ENTs will let people like us us have it.
It wont be the ENTs' decision. It will be the almighty gods of the FDA. Also, this technology will be replicated in China and Mexico and other countries. If not here, I believe that there will be overseas alternatives, if there arent already some.
 
Not sure about that. But whatever. Let's not get ahead of ourselves. FX isn't proven for anything at all yet :/
We shouldnt get ahead of ourselves but I know very damn well that the ENT will not be the gatekeepers of who gets this treatment and who doesnt. It will be the FDA. And like I said, when/if this technology gets out you'll be able to fly to some Asian country or something and get it, probably even alot cheaper.
 
upload_2018-8-27_21-25-18.png

An acute anti hearing loss agent confused as a treatment for chronic tinnitus is going to get normies super hype false hope. In all honestly I hope it does succeed for the treatment of acute tinntius and to prevent NMDA from causing more hearing loss.
upload_2018-8-27_21-25-38.png

Why is all the information about this "NMDA centric semi peripheral tinnitus hypothesis" not available, all the papers I read said tinnitus was completely neurological and opposites of what they are saying.

Auris Medical and Otonomy share the same fringe hypothesis and they have not shared the science of it with the public, and NMDA is known to cause hair cell death. Roland Schaette's tinnitus mechanism model said tinnitus was "Less input from the audiotory nerve+ more input from the Dorsal cochlear nucleus compensating" not "excitability of the audiotory nerve to excitability of the dorsal cochlear nucleus"

obviously someone is wrong and the NMDA centric model doesn't account for ear plug experiments, sudden sensori-neural hearing loss, severed audiotory nerve in an accident. If there is something Auris Medical and Otonomy knows that the public doesn't it'd be kind of them to explain the science to the public instead of the I said so argument.

Expect normies to get super hype about OTO-313 while I literally just face palm.
 

Log in or register to get the full forum benefits!

Register

Register on Tinnitus Talk for free!

Register Now