MemberHe's lucky he didn't. I suffered it at birth and it's been debilitating ever since.
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- Thread starter threefirefour
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Mr Worried
Member
- Sep 9, 2017
- 199
- Tinnitus Since
- august 2017-july 2018
- Cause of Tinnitus
- Ripped the tag off a mattress
Nathan
Member
- Jul 28, 2018
- 164
- 23
- Tinnitus Since
- 06/2018
- Cause of Tinnitus
- Loud Music, Concert, Bad Luck
Come on in, feel free to do some looking. Stay a while because somethings always cooking.
PetitGarsTimide
Member
- Jan 6, 2018
- 225
- Tinnitus Since
- 2016
- Cause of Tinnitus
- Dumb teenager who listened to loud music everytime
MPP Research Team Report:
So, very interesting.
I have heard before that Tumeric has anti cancer properties. Well, I've been trying to find a backdoor to the method of inducing hair cell regeneration and I came across this paper which is about ly411575 regenerating mice cochlear hair cells.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557215/#!po=10.9375
From that:
"In neonatal mice, downregulation of Notch signaling also induces SC (supporting cells, I'm assuming these are progenitor cells) proliferation, whereas in adults it leads to more hair cells via transdifferentiation."
More on Notch signalling:
https://en.m.wikipedia.org/wiki/Notch_signaling_pathway
So I was curious to see if any foods contain properties that downregulate notch signalling and found this:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780034/
"We sought to evaluate the role of Notch1 in hepatocellular cancer (HCC), and evaluate the therapeutic efficacy of curcumin, a known Notch1 inhibitor."
Curcumin:
https://en.m.wikipedia.org/wiki/Curcumin
Here is a ScienceMag report saying there's nothing beneficial about curcumin:
http://blogs.sciencemag.org/pipeline/archives/2017/01/12/curcumin-will-waste-your-time
In the comments someone left this interesting comment:
"That's not true. I have been taking curcumin capsules for more than a year. It improved my short time memory， improved the symptoms of gingivitis, the longvida one even improved my hearing and I also can feel it improved my cerebrovascular，reduced the risk of getting stroke"
And I found this: (curcumin is in tumeric)
https://www.turmericforhealth.com/turmeric-benefits/5-benefits-of-turmeric-in-tinnitus
So I'm about to take supreme mega doses of curcumin and super saturate my flesh with this stuff and see if it makes my tinnitus go away.
Update: found this:
https://www.ncbi.nlm.nih.gov/m/pubmed/26978516/
I'm gonna try it though.
Another update:
Xanthahumol is another notch inhibitor:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0127464
https://en.m.wikipedia.org/wiki/Xanthohumol
I'm going to try both of these things together.
So, very interesting.
I have heard before that Tumeric has anti cancer properties. Well, I've been trying to find a backdoor to the method of inducing hair cell regeneration and I came across this paper which is about ly411575 regenerating mice cochlear hair cells.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557215/#!po=10.9375
From that:
"In neonatal mice, downregulation of Notch signaling also induces SC (supporting cells, I'm assuming these are progenitor cells) proliferation, whereas in adults it leads to more hair cells via transdifferentiation."
More on Notch signalling:
https://en.m.wikipedia.org/wiki/Notch_signaling_pathway
So I was curious to see if any foods contain properties that downregulate notch signalling and found this:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780034/
"We sought to evaluate the role of Notch1 in hepatocellular cancer (HCC), and evaluate the therapeutic efficacy of curcumin, a known Notch1 inhibitor."
Curcumin:
https://en.m.wikipedia.org/wiki/Curcumin
Here is a ScienceMag report saying there's nothing beneficial about curcumin:
http://blogs.sciencemag.org/pipeline/archives/2017/01/12/curcumin-will-waste-your-time
In the comments someone left this interesting comment:
"That's not true. I have been taking curcumin capsules for more than a year. It improved my short time memory， improved the symptoms of gingivitis, the longvida one even improved my hearing and I also can feel it improved my cerebrovascular，reduced the risk of getting stroke"
And I found this: (curcumin is in tumeric)
https://www.turmericforhealth.com/turmeric-benefits/5-benefits-of-turmeric-in-tinnitus
So I'm about to take supreme mega doses of curcumin and super saturate my flesh with this stuff and see if it makes my tinnitus go away.
Update: found this:
https://www.ncbi.nlm.nih.gov/m/pubmed/26978516/
I'm gonna try it though.
Another update:
Xanthahumol is another notch inhibitor:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0127464
https://en.m.wikipedia.org/wiki/Xanthohumol
I'm going to try both of these things together.
Last edited:
MPP Research Team Report:
So, very interesting.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4557215/#!po=10.9375
From that:
"In neonatal mice, downregulation of Notch signaling also induces SC (supporting cells, I'm assuming these are progenitor cells) proliferation, whereas in adults it leads to more hair cells via transdifferentiation."
More on Notch signalling:
https://en.m.wikipedia.org/wiki/Notch_signaling_pathway
So I was curious to see if any foods contain properties that downregulate notch signalling and found this:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2780034/
"We sought to evaluate the role of Notch1 in hepatocellular cancer (HCC), and evaluate the therapeutic efficacy of curcumin, a known Notch1 inhibitor."
Curcumin:
https://en.m.wikipedia.org/wiki/Curcumin
Here is a ScienceMag report saying there's nothing beneficial about curcumin:
http://blogs.sciencemag.org/pipeline/archives/2017/01/12/curcumin-will-waste-your-time
In the comments someone left this interesting comment:
"That's not true. I have been taking curcumin capsules for more than a year. It improved my short time memory， improved the symptoms of gingivitis, the longvida one even improved my hearing and I also can feel it improved my cerebrovascular，reduced the risk of getting stroke"
And I found this: (curcumin is in tumeric)
https://www.turmericforhealth.com/turmeric-benefits/5-benefits-of-turmeric-in-tinnitus
So I'm about to take supreme mega doses of curcumin and super saturate my flesh with this stuff and see if it makes my tinnitus go away.
Update: found this:
https://www.ncbi.nlm.nih.gov/m/pubmed/26978516/
I'm gonna try it though.
Another update:
Xanthahumol is another notch inhibitor:
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0127464
https://en.m.wikipedia.org/wiki/Xanthohumol
I'm going to try both of these things together.
Very insightful post @JohnAdams. I will look into Tumeric!
I know I tagged some of you in the original post, but this poster reported that her tinnitus was completely GONE after taking NAC.
https://www.tinnitustalk.com/threads/getting-a-dental-filling-next-week.30824/#post-362878
I wonder how much of a roll Glutathione plays a roll in everyday tinnitus. I know it can help prevent damage and has a strong anti-oxidant effect. It has been proven to reduce oxidation stress in the brain. I wonder if it does something similar to the auditory system as well. I'm not saying this will cure all tinnitus, I am just curious about the mechanisms at play here.
https://www.tinnitustalk.com/threads/getting-a-dental-filling-next-week.30824/#post-362878
I wonder how much of a roll Glutathione plays a roll in everyday tinnitus. I know it can help prevent damage and has a strong anti-oxidant effect. It has been proven to reduce oxidation stress in the brain. I wonder if it does something similar to the auditory system as well. I'm not saying this will cure all tinnitus, I am just curious about the mechanisms at play here.
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