My Posting Place

[PetitGarsTimide]

new vlog everyday

 

[Contrast]

new vlog everyday

aweeeeeeeesomeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeee

 

[PetitGarsTimide]

aweeeeeeeesomeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeeee

Thank you means a lot for me don't forget to support me on patreon

 

[threefirefour]

new vlog everyday

Now that's editing

 

[PetitGarsTimide]

Now that's editing

was waiting for your review for ages

 

[PetitGarsTimide]

Guys (edit: or girls idk) i've one question for you i see your messages sometimes especially in "research news" because that's the only place I went on this forum before I discovered this cancer thread but more seriously how do you consider your science skills in term of "hearing" ? if you read real science papers, you understand all or not ?
i'm interested by what you think are the most promising things

edit: sorry if i made english mistakes

 

[threefirefour]

Guys (edit: or girls idk) i've one question for you i see your messages sometimes especially in "research news" because that's the only place I went on this forum before I discovered this cancer thread but more seriously how do you consider your science skills in term of "hearing" ? if you read real science papers, you understand all or not ?
i'm interested by what you think are the most promising things

edit: sorry if i made english mistakes

Yeah I read papers and I'm pretty sure Jon does too. Without saying what I'm doing in real life, I'm a science major, and go through papers like this all the time. I read a lot about hearing so I have a pretty good grasp of what's up.

The soonest: Susan shore.
The best for hearing: frequency therapeutics.
The best for tinnitus: I don't know, but RL-81 is a good medicine for all tinnitus sufferers, when the better version comes out.

For repairing permanent brain damage resulting in tinnitus, I don't know, but it will most likely be about reversing neuroplasticity, or breaking the "clusters" of active neurons that cause tinnitus.

 

[PetitGarsTimide]

Yeah I read papers and I'm pretty sure Jon does too. Without saying what I'm doing in real life, I'm a science major, and go through papers like this all the time. I read a lot about hearing so I have a pretty good grasp of what's up.

The soonest: Susan shore.
The best for hearing: frequency therapeutics.
The best for tinnitus: I don't know, but RL-81 is a good medicine for all tinnitus sufferers, when the better version comes out.

For repairing permanent brain damage resulting in tinnitus, I don't know, but it will most likely be about reversing neuroplasticity, or breaking the "clusters" of active neurons that cause tinnitus.

that's pretty interesting !
I think i'm also on what you can call a "science major" (i don't really know what is the equivalent in my country but I assume that "science major" means that is just university in science field) but i'm just in first year.

I have a lot of hopes in Frequency therapeutics too (the disappointment will only be greater if they fail)
Susan shore's device seems also great but I don't really understand how it works (sound therapy and eletric shock ?)

And for RL-81 i don't even know what this is but it seems it's something which has already been realased so maybe bad side effects ?

 

[threefirefour]

that's pretty interesting !
I think i'm also on what you can call a "science major" (i don't really know what is the equivalent in my country but I assume that "science major" means that is just university in science field) but i'm just in first year.

I have a lot of hopes in Frequency therapeutics too (the disappointment will only be greater if they failed)
Susan shore's device seems also great but I don't really understand how it works (sound therapy and eletric shock ?)

And for RL-81 i don't even know what this is but it seems it's something which has already been realased so maybe bad side effects ?

Okay. The three all have great potential. I think frequency therapeutics will ultimately succeed, but it will be at least a few decades (or maybe you could get it quick in a country like Thailand where the FDA isn't an issue. I don't know how the legality of that would work).

Susan shores device works by stimulating the DCN, which is an important area of the brain to focus on for somasensory sufferers. I assume It works like ACRN, where it uses deep brain stimulation to target active clusters of neurons that cause tinnitus. By attacking them, the tinnitus reduces because these regions are out of sync.

RL-81 has been released before, and got rid of tinnitus for a lot of sufferers. It's an epileptic medicine. It had some bad side effects, but now a version that's supposed to be 15 times stronger, and no side effects, is being tested.

 

[Localboy]

RL-81 has been released before, and got rid of tinnitus for a lot of sufferers. It's an epileptic medicine. It had some bad side effects, but now a version that's supposed to be 15 times stronger, and no side effects, is being tested.

Not true, RL-81 has never been released, it was TROBALT Retigabine that was...

 

[threefirefour]

Not true, RL-81 has never been released, it was TROBALT Retigabine that was...

I see. So I was confused on the name again. So then RL-81 is the product being tested? I thought it was a different name for trobalt.

 

[PetitGarsTimide]

Okay. The three all have great potential. I think frequency therapeutics will ultimately succeed, but it will be at least a few decades (or maybe you could get it quick in a country like Thailand where the FDA isn't an issue. I don't know how the legality of that would work).

Susan shores device works by stimulating the DCN, which is an important area of the brain to focus on for somasensory sufferers. I assume It works like ACRN, where it uses deep brain stimulation to target active clusters of neurons that cause tinnitus. By attacking them, the tinnitus reduces because these regions are out of sync.

RL-81 has been released before, and got rid of tinnitus for a lot of sufferers. It's an epileptic medicine. It had some bad side effects, but now a version that's supposed to be 15 times stronger, and no side effects, is being tested.

Thank you for the answer

I really hope it won't take decade for frequency to hit the market

I'm not familiar at all with the FDA and the clinical trials protocols ...

If i understand correctly they try theirs drugs for the phase 1 on candidates to test if the drug is safety (I think they were not able to measure the effectiveness because the candidates was about to get an implant)

but it's still confusing to me because I read all over that phase 2 is gonna take 3-5 years but why is this so long ?

I mean if they find candidates for the trials, they just have to inject the drugs and wait a few days/weeks no ? (obviously i'm missing something here, maybe the FDA has so many request and that's why it takes so many times ? maybe they have to watch the effects of the drugs in long terms but I assume that it was the purpose of the phase 1 ?)

Would be glad to hear your explanations about that

Besides this it's still very encouraging to see that things are moving

 

[threefirefour]

Thank you for the answer

I really hope it won't take decade for frequency to hit the market

I'm not familiar at all with the FDA and the clinical trials protocols ...

If i understand correctly they try theirs drugs for the phase 1 on candidates to test if the drug is safety (I think they were not able to measure the effectiveness because the candidates was about to get an implant)

but it's still confusing to me because I read all over that phase 2 is gonna take 3-5 years but why is this so long ?

I mean if they find candidates for the trials, they just have to inject the drugs and wait a few days/weeks no ? (obviously i'm missing something here, maybe the FDA has so many request and that's why it takes so many times ? maybe they have to watch the effects of the drugs in long terms but I assume that it was the purpose of the phase 1 ?)

Would be glad to hear your explanations about that

Besides this it's still very encouraging to see that things are moving

I'm no expert, but I think it will take more than a decade. The reason trials take so long is because of a lot of the legal loops. I think phase 2 will be a success because of the revelation we had on their progress in January. Progress isn't linear, it happens in leaps.

 

[PetitGarsTimide]

I'm no expert, but I think it will take more than a decade. The reason trials take so long is because of a lot of the legal loops. I think phase 2 will be a success because of the revelation we had on their progress in January. Progress isn't linear, it happens in leaps.

Ok tks again

That's all i wanted to know and hope everythings will going well

 

[Tempest]

I think it will take more than a decade

 

[Contrast]

Okay. The three all have great potential. I think frequency therapeutics will ultimately succeed, but it will be at least a few decades (or maybe you could get it quick in a country like Thailand where the FDA isn't an issue. I don't know how the legality of that would work).

You really think the FDA is gonna take 20 years or bio tech firms are gonna move to Thailand under this man.

Dude, this is one case Trump can help us, he'll cut funding but he will also cut regulations. So if enough private investors fund frequency it could really be in 3-5 years.

 

[threefirefour]

View attachment 15308
You really think the FDA is gonna take 20 years or bio tech firms are gonna move to Thailand under this man.

Dude, this is one case Trump can help us, he'll cut funding but he will also cut regulations. So if enough private investors fund frequency it could really be in 3-5 years.

I agree because he helped us with hearing aids. A cutback on research regulations would be a godsend.

 

[PetitGarsTimide]

View attachment 15307

feel you

View attachment 15308
You really think the FDA is gonna take 20 years or bio tech firms are gonna move to Thailand under this man.

Dude, this is one case Trump can help us, he'll cut funding but he will also cut regulations. So if enough private investors fund frequency it could really be in 3-5 years.

 

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YO GUYS MY POSTING PLACE HAS OVER 10,000 VIEWS!

 

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Contrast explain me when your love for luan began

I've always liked Nicktoons, around mid-late 2016 when I first started watching the Loudhouse the character just clicked with me. She is funny and a comedian like myself and also gives us this psycho girl vibe in some episodes.

 

[PetitGarsTimide]

I've always liked Nicktoons, around mid-late 2016 when I first started watching the Loudhouse the character just clicked with me. She is funny and a comedian like myself and also gives us this psycho girl vibe in some episodes.

View attachment 15323

I miss the old shows on nickelodeon it was the only tv channel i watched when i was a "kid" but the magic does not work for me anymore ...

 

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Anyone wanna hop on minetest?

 

[threefirefour]

Anyone wanna hop on minetest?

I'm in bed. Wish I could ;_;

 

[Localboy]

I'm in bed too

 

[threefirefour]

I'm in bed too

Do you play minetest?

 

[PetitGarsTimide]

Fortnite ?

 

[threefirefour]

Could anyone float me $20,000 so I can finally be average?

 

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[PetitGarsTimide]

View attachment 15329

View attachment 15330

libre office is the shit

 

[threefirefour]

Whenever I change my occupation under personal details.