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- Thread starter threefirefour
- Start date
I have been wondering about your case. It seems that this drug, in general, has a very temporary effect of tinnitus except as a preventive when given acutely after noise trauma.
I wonder if blocking your NMDA receptor temporarily (through Neuro feedback/homeostasis) increased your glutamate release. I very strongly suspect this is a temporary spike. Once the drug is cleared from the body, i believe you will start to go back to baseline. Hang in there.
MemberSometimes, I take 1 or 1.5 grams of GABA and it knocks me out to sleep. It helps to ignore Tinnitus, because I'm just too tired to worry or stress about anything, after taking GABA.
I feel like taking it before sleep, helps me sleeping longer for an hour or two.
By the way, some people take L-Theanine and drink a few beers to that, and it makes them quite sleepy for a few hours. I don't think natural sleep aids have been tried by too many people, on this forum, which is not good, because there are many ways to experiment with them. Even taking a stupid peppermint oil capsule, helps me in taking a poo in the middle of the night.
I feel like taking it before sleep, helps me sleeping longer for an hour or two.
By the way, some people take L-Theanine and drink a few beers to that, and it makes them quite sleepy for a few hours. I don't think natural sleep aids have been tried by too many people, on this forum, which is not good, because there are many ways to experiment with them. Even taking a stupid peppermint oil capsule, helps me in taking a poo in the middle of the night.
That's about all Amitriptyline (Elavil) does. Except it makes me sleepy 24 hours or whatever.
JulianBrumbelow
Member
- Apr 5, 2018
- 219
- Tinnitus Since
- 03/14/2017
- Cause of Tinnitus
- loud headphones audio work
Depending on the study you read and the formulation of GABA, it does appear to cross the BBB.
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4594160/
Elmer B Fuddled
Member
- Feb 11, 2019
- 1,329
- Tinnitus Since
- 2017
- Cause of Tinnitus
- plugged nasal eustachian tube
Maybe a good system cleanse wash out the bad stuff flowing in your system, it's not rocket science, but if we don't flush out the shit we put in it keeps building up, lots of water, and a glass of apple cider vinegar with the mother. I found that researching for a natural way to flush the drugs out of my own system. It did help, but not overnight. Only just a thought.
Elmer B Fuddled
I should really have said it *can* make tinnitus worse over time when you try to go off of them, (especially if not done properly) and have both been associated with increased tinnitus (from baseline) and hyperacusis (sometimes severe). This can also happen if tolerance to the drug happens, which does to many people after a long time--but not everyone. The short acting ones (ie *not* Clonazepam) tend to be the most problematic though.
I had to take benzos when I had much worse vestibular issues and I did a lot of reading on them. They have their place but they scare me.
Benzo withdrawal and long term use has been associated with a lot of sensory disturbances. Some people seem way more susceptible than others, though.
$1,500 USD per NSF certification of a product
Zenith Labs has almost 20 products on market all use to claim NSF certification.
1,500 x 20 = $30,000
That is the cost if Zenith Labs had actually certified their products with the NSF but they didn't.
JulianBrumbelow
Member
- Apr 5, 2018
- 219
- Tinnitus Since
- 03/14/2017
- Cause of Tinnitus
- loud headphones audio work
They also claimed their entire facility was inspected by the NSF and FDA which was a lie.
I have no idea where they are making the supplements but it's not in Illinois that's the shipping company. Once again Daniel use to be a pharmacist but I ultimately have no clue where the supplements are coming from.
Director- Oct 24, 2017
- 849
- Tinnitus Since
- 10/2017
- Cause of Tinnitus
- one-sided hearing loss (of unknown origin)
That drug didn't get anywhere near your brain friend. I'm pretty sure that your problem is with your cochlear synapses.
Did that drug make your existing tinnitus louder or did it add new tones that are louder or both?
It acts on NDMA. As FGG thinks too, it must have messed with my glutamate, or something in there.
It spread my right ear ringing to my left ear (which was not injected) then gave it an evolution stone to make it louder and even higher pitched.
I'm telling you man, there is zero chance this stuff got to your brain. It wasn't even injected into your bloodstream. It was injected into your middle ear. Some seeped into your cochlea via the RWM, cochlear fluid is separated from your brain by the BLB, then your systemic blood flow, and then the BBB, and the rest went down your Eustachian tube. There are NDMA receptors on your cochlear nerves, on all your nerves, not just on your brain neurons. Whatever this drug did, it didn't even touch your brain.
If this drug were meant to act on your brain they would have either given you an injection into your blood or an epidural. The site of action for this is the synapses on your cochlear nerve, nowhere near your brain which is why they injected it into your eardrum.
This drug acts on the cochlear nerve where the red arrow is pointing. There is not a circulatory path from here to anywhere in your brain.
HootOwl
Member
Exactly.
They are assuming what I believe, that the tinnitus signal is generated right there.
It says clearly in the paperwork that the they don't know the effects the drug has on the body. Even though it was injected through my ear, they took my vitals and have done bloodwork almost everytime I've gone in so far, and also warned about abstaining from sex or using protection during the study. So long as it could be absorbed, it could reach the brain, which is how it spread to my good ear.
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