My Trip to Bangkok: Stem Cell Treatment [Comments]

Stem Cell 21 primarily uses mesenchymal stem cells, though I'm told they will have induced pluripotent stem cells in 2020. Further, their delivery sites can include the ear, nasal passages and systemic circulation. This Dallas one looks like systemic only, and with poorer choices for treating tinnitus (adipose and bone marrow). I doubt you would get any benefit for tinnitus from them.
 
Until the US allow scientifics to fully research stem cell treatments to their full potential there will be no progress on this field. It is a shame that religion and absurd beliefs hamper scientific progress and erase the slim hope people who suffer from a lot of diseases and health conditions may have.
 
It is a shame that religion and absurd beliefs hamper scientific progress and erase the slim hope people who suffer from a lot of diseases and health conditions may have.
You're talking about embryonic stem cells. The absurd beliefs your talking about are the belief that little babies in the womb should not be violently dismembered and ripped out. Guess what? They don't even need to end the life of an innocent to get embryonic stem cells anymore so cool it with the bloodlust.

https://news.harvard.edu/gazette/st...s-create-embryonic-stem-cells-without-embryo/
 
@attheedgeofscience

Thanks for sharing your experiences. It is interesting you are able to breathe better through your nose. Do you have any scientific theory as to why? It seems it could have regrown damaged cilia allowing better passage of mucus and pathogens from your sinuses. Or it could be the nerves in sinuses were repaired so they perform better. Interested in your thoughts.
 
Stem Cell 21 primarily uses mesenchymal stem cells, though I'm told they will have induced pluripotent stem cells in 2020. Further, their delivery sites can include the ear, nasal passages and systemic circulation. This Dallas one looks like systemic only, and with poorer choices for treating tinnitus (adipose and bone marrow). I doubt you would get any benefit for tinnitus from them.
Sorry to crush the hope, but I'm not so sure if iPSCs will be an option. I read the following in a study:

The basic paradigm in the use of PSCs for cell therapy purposes is that they are first differentiated into the desired cell types of interest, and the resulting specialized tissue-specific cells are then transplanted as cell suspensions or more complex tissue constructs into patients. The differentiation step is crucial because if proliferating, undifferentiated PSCs are directly injected, they would form tumors called teratomas due to their highly proliferative nature and broad differentiation potential. (https://stemcellres.biomedcentral.com/articles/10.1186/s13287-019-1455-y).
So it seems you can't just inject iPSCs into the ear because of tumor risk if I understand this correctly.
 
Sorry to crush the hope, but I'm not so sure if iPSCs will be an option. I read the following in a study:

The basic paradigm in the use of PSCs for cell therapy purposes is that they are first differentiated into the desired cell types of interest, and the resulting specialized tissue-specific cells are then transplanted as cell suspensions or more complex tissue constructs into patients. The differentiation step is crucial because if proliferating, undifferentiated PSCs are directly injected, they would form tumors called teratomas due to their highly proliferative nature and broad differentiation potential. (https://stemcellres.biomedcentral.com/articles/10.1186/s13287-019-1455-y).
So it seems you can't just inject iPSCs into the ear because of tumor risk if I understand this correctly.
You do. They have to be induced, which can be successfully done, but they never replied to my email about whether they can do it.
 
You do. They have to be induced, which can be successfully done, but they never replied to my email about whether they can do it.
If I unterstand it correctly you would first have to make iPSCs (which is mostly established by now how to do it, although still quite complicated), but then you would have to differentiate them into hair cells and then inject them so you don't get teratoma (man they are disgusting :D). But I don't know if such hair cells would integrate into the cochlea in the correct way. FX-322 seems more precise in that matter. Although we can't ignore that stem cells have benefited other users here before (and I've added them to the list of my options in the case I can't deal with my tinnitus anymore, though I'm waiting a couple months/years first to see whether I can habituate to this new louder noise). :) But umbilical cord blood stem cells, the next best thing after IPSCs, are multipotent stem cells and not pluripotent, so they can't proliferate without limit, so there's little / no risk with tumor formation.
 
All I know is Ozzy Osbourne apparently is doing much better after Stem Cell treatment in Panama for Parkinson's, so there must be something promising to it.

I'm hoping the Coronavirus exposes the lack of treatment and speed of cures due to FDA red tape, trials at a snail pace, and ineffective medicine. Sad but true, it's time for the US Gov to look at where the money is really going and start questioning how come since the dawn of time we still can't cure the common cold. Unfortunately it takes a disaster sometimes to change the status quo.
 
He still purports to be fine with minimal tinnitus. He is still on here every once in a while.
So happy to know that someone has been almost cured! Almost 8 years have passed since the beginning of this thread, I hope the science has improved and the treatments are somewhat cheaper and more accessible.

Does anybody have any update on these stem cell treatments?
 
So happy to know that someone has been almost cured! Almost 8 years have passed since the beginning of this thread, I hope the science has improved and the treatments are somewhat cheaper and more accessible.

Does anybody have any update on these stem cell treatments?
I think the notion that stem cell therapy is still in its infancy holds true across most of healthcare - if you do get stem cell treatment, it's more of a shotgun approach to see what sticks.
 
I think the notion that stem cell therapy is still in its infancy holds true across most of healthcare - if you do get stem cell treatment, it's more of a shotgun approach to see what sticks.
I read somewhere that the problem with stem cell therapy is uncontrollable reproduction of the injected cells and hence cancer, do you perhaps know if this problem has been solved throughout these years?
 
I read somewhere that the problem with stem cell therapy is uncontrollable reproduction of the injected cells and hence cancer, do you perhaps know if this problem has been solved throughout these years?
Reports of cancer from SCs are rare in general. There actually isn't too much scientific evidence proving SCs exacerbate cancer growth and it's a theory for the most part. The thing with SCs is that it's difficult to target a specific area or malady with them and the shotgun metaphor is likely accurate. Clinics do things to try and help along the targeted use of SCs but in reality it helps very little. Mostly, SCs will go where they are needed which is why sometimes people with comorbidities see improvements in many areas while getting treatment. I believe that SCs can help things like ear disorders but you take a gamble as to how much improvement you will see.

Stem Cell therapy gets a bad rap from the FDA because it's unregulated and many clinics performing these therapies are ripping off their patients and injecting potentially harmful substances. I have read a story about one clinic injecting people with steroids, albumin and other medications that would make the patient feel like a kid again for the proceeding days but shortly after fall back into the same chronic condition.

If you have the means and go to a reputable clinic, you will likely get some improvement in any ear disorder but no one can tell you how much. The real future of stem cells is using mRNA to reprogram them to cure chronic conditions. This is happening right now. We have effectively "cured" sickle cell disease, beta thalassemia, pyruvate kinase disease, etc. These blood disorders were basically a life sentence before but over the last 12 months, science has used SC and mRNA to rewrite DNA and remove genetic errors. This is the future of medicine. Unfortunately for the US (and Canada) we are still very far behind in this technology mainly because of the political issues surrounding embryonic stem cells. Today MSC can be used but the technology as a whole is far behind that of other countries. This is why people are going to Bangkok to get SC treatment for their ears or to Germany to get cancer treatment (which I believe BioNtech will have cures for some types of cancers in the next 24 months).
 
many clinics performing these therapies are ripping off their patients and injecting potentially harmful substances. I have read a story about one clinic injecting people with steroids, albumin and other medications that would make the patient feel like a kid again for the proceeding days but shortly after fall back into the same chronic condition.
Unfortunately after getting tinnitus I realised how many scams there are for different illnesses around the world. I guess waiting is the only option. I hope someone finds the Penicillin of the tinnitus soon.
 
I believe @attheedgeofscience had a good response to the treatment amongst others. I believe his tinnitus was brought on by autoimmune disease if I am not mistaken. The others who did well with this treatment, I cannot remember their cause.
This would explain why his was a success.

Stem cells appearently act as immune-modulators, and that's all they do. They can not fix anything in the brain after a certain time-limit (hours to a couple of days).

In ATEOS's case the stem cells must have simply repaired his immune system which stopped his tinnitus.

I'm now more convinced than ever that stem cells will do nothing for me.
 
Chloe Sohl, the tinnitus story that inspired ATEOS to go ahead with it turns out to be also a case of autoimmune.

I don't think there's a single successful report from a noise-induced case.
 
Chloe Sohl, the tinnitus story that inspired ATEOS to go ahead with it turns out to be also a case of autoimmune.

I don't think there's a single successful report from a noise-induced case.
@LJMD said his tinnitus was noise-induced.

I haven't delved deeply into every small case to be honest. I'll still probably go get the treatment anyway.
 
This would explain why his was a success.

Stem cells appearently act as immune-modulators, and that's all they do. They can not fix anything in the brain after a certain time-limit (hours to a couple of days).

In ATEOS's case the stem cells must have simply repaired his immune system which stopped his tinnitus.

I'm now more convinced than ever that stem cells will do nothing for me.
You shouldn't opt for a stem cell treatment unless you're prepared to take a chance.

But ATEOS has never said that his tinnitus was caused by an autoimmune disease.

Indeed, he is not sure what caused the onset. He has speculated it might have been a hit to the ear.
 
You shouldn't opt for a stem cell treatment unless you're prepared to take a chance.

But ATEOS has never said that his tinnitus was caused by an autoimmune disease.

Indeed, he is not sure what caused the onset. He has speculated it might have been a hit to the ear.
From what I've read so far (not much), ATEOS had mild tinnitus since childhood. Could this be the autoimmune disorder that @jer here is referring to? ATEOS said there could be made no doubts about the efficacy of the stem cells, since it could by no chance be a coincidence, seeing improvements in that tone so suddenly after so many years. He got another tone by (possibly) a hit to the ear some months before the treatment, and about 3 months after the treatment he saw improvements in that too. That tone could simply have resolved on its own by that time, coincidentally. Don't you think so?

Just to clear my point up; The stem cells likely fixed his immune system, ridding him off the tone he had had since childhood, and by 3 months the tone he got after the hit had coincidentally resolved naturally and with time, like a lot of cases of tinnitus do.

We have to weigh all this in before considering this.
 
From what I've read so far (not much), ATEOS had mild tinnitus since childhood. Could this be the autoimmune disorder that @jer here is referring to? ATEOS said there could be made no doubts about the efficacy of the stem cells, since it could by no chance be a coincidence, seeing improvements in that tone so suddenly after so many years. He got another tone by (possibly) a hit to the ear some months before the treatment, and about 3 months after the treatment he saw improvements in that too. That tone could simply have resolved on its own by that time, coincidentally. Don't you think so?

Just to clear my point up; The stem cells likely fixed his immune system, ridding him off the tone he had had since childhood, and by 3 months the tone he got after the hit had coincidentally resolved naturally and with time, like a lot of cases of tinnitus do.

We have to weigh all this in before considering this.
This study here seems very promising:

Safety of Autologous Umbilical Cord Blood Therapy for Acquired Sensorineural Hearing Loss in Children

It doesn't say how they acquired SNHL though.

For me, it's definitely worth at least trying the stem cell treatment. It won't make it worse anyway and there are no side effects. I just want to visit my ENT first but I need to wait another month to see him.

It is very expensive though too but that isn't an issue for me right now thankfully, otherwise I may have to think harder about it but would probably still try to do it.
Is he still active? If that's true then that would be amazing.

How long did he have it?
He's not active anymore so one would assume he is better. You can go through his posts to see.
 
Here's the link to Stem Cells 21 tinnitus treatment section
And now they seem to have deleted this section.

Which could only mean that they've had more failures than wins for patients with tinnitus. Being truthful like that gives them a lot of credibility though, so maybe the rest of what they are saying is actually true. Maybe they actually can treat this broad spectrum of neurological disorders that they claim to be able to on their page. This gives me a lot of hope, since I'm mainly looking to have my neuro-disorder treated.
 

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