New Sleeping/Insomnia Medicine: Dayvigo (Lemborexant) — Here's My Experience

[Chinmoku]

As my tinnitus gets worse I struggle to sleep and as soon as I wake up it's over and I'm stuck in bed with torture. I don't want to increase benzos or take Z/GABA drugs.

Quetiapine and Mirtazapine are options I might look at but I'd rather try an Orexin inhibitor. Problem is the international online pharmacies I found online don't sell it. There is no generic as it is a new drug, so I suspect that it can be very expensive.

Can anyone give an indication of the price range and some tips on how we could purchase it internationally? I tried a few web searches but got nothing.

@hans799? @Lyta Norman? Thanks in advance.

 

[JayZee]

Can anyone give an indication of the price range and some tips on how we could purchase it internationally? I tried a few web searches but got nothing.
Thanks in advance.

In Canada, a 5 mg pill seems to go for about $1.75 per pill which is about $1.35 in US dollars. However, I have no idea what the pills actually cost in USA, since they often charge more.

 

[Óscar PP]

Grey market (just Google it).

I tried but can't find any provider that ships them to the EU.

 

[Brenda in NJ]

I know this is an older post but I just got Dayvigo from my doctor. Really struggling with sleep. And even worse since stopping Seroquel and upping antidepressant. I was concerned about combining it with my AD as on Drugs.com it says it has a major reaction. My AD seems to react with everything. But my doctor says it just means we can't go on a dose higher than 5 mg. But nervous this will upset the apple cart since I'm in withdrawal, etc.

Anyone else on here take Dayvigo with other meds?

 

[Óscar PP]

I found a provider, I'll buy it if Mirtazapine stops working.

 

[Óscar PP]

The EMA has approved Daridorexant in the EU.

https://www.ema.europa.eu/en/medicines/human/EPAR/quviviq

 

[Meliora]

Additionally, I feel that a sleep aid that blocks wakefulness rather than trying to induce sleepiness through manipulation of GABA receptors can be very beneficial. I have no side effects with this, and I cannot take Valerian (makes me WIDE awake) and many other herbal and prescription meds seem to cause my body to react in the opposite of what I am going for. Not a fan of Big Pharma. But this has been an (albeit temporary) godsend. I realize it doesn't translate into being the answer for everyone.

Do you still take Dayvigo? Does it work long term? Are you in the US?

 

[Tweaker]

The MHRA in the UK have also approved this medication under name of Quivivq.

 

[ccpjc]

Is anyone still using Dayvigo?

I recently got a prescription for it, but I'm cautious about taking it due to concerns that it might spike my tinnitus. I suspect Melatonin spikes my tinnitus as well, though I'm not entirely sure yet.

 

[JayZee]

Is anyone still using Dayvigo?

I recently got a prescription for it, but I'm cautious about taking it due to concerns that it might spike my tinnitus. I suspect Melatonin spikes my tinnitus as well, though I'm not entirely sure yet.

I've been using Dayvigo for a few years now, and it's the best sleep aid I've found so far. It hasn't had any negative impact on my tinnitus, and I don't experience long-term drowsiness the next day.

If it could actually lower tinnitus—like Benadryl sometimes does—it would be even better and the perfect sleeping pill for people like us. For now, though, it's still excellent for me.

 

[RunningMan]

Is anyone still using Dayvigo?

I recently got a prescription for it, but I'm cautious about taking it due to concerns that it might spike my tinnitus. I suspect Melatonin spikes my tinnitus as well, though I'm not entirely sure yet.

I took Dayvigo temporarily, but I have been on Quviviq (daridorexant) for 9 months, which is the newer medication mentioned earlier in this thread that is in the same DORA class as Dayvigo. I started on Quviviq and jumped to the max dose quickly, but after 6 months, I switched to the max dose of Dayvigo to see if it would work any better. But I didn't sleep any better with Dayvigo, and I thought it left me groggier in the morning, so I went back to Quviviq. Neither made a noticeable difference in my tinnitus. I think it helps my sleep, but not enough. My biggest problem was waking up after too little sleep, and with Quviviq, I still wake up much earlier than I would like to. Last night, I actually woke up after 2 hours feeling wide awake and couldn't get back to sleep for quite a while.