New University of Michigan Tinnitus Discovery — Signal Timing

[kelpiemsp]

Shorter onset? Like have had it less? According to their paper the two people who didn't have a significant reduction in TFI had tinnitus for less than a year. Granted two people is an extremely tiny sample size, but with our limited information it seems people who have had it longer benefit more.

Aye. But in full study guidelines, preference is for T less than 5 years. That is only preference. They could have many reasons that don't have much to do with noise reduction. I.E. maybe people who have had T for over 5 years rate its intrusiveness lower, regardless of volume. And that would impact the study. I do not think this decision is based on a belief that it is less beneficial for people who have it a long time. I can ask though!

 

[threefirefour]

Aye. But in full study guidelines, preference is for T less than 5 years. That is only preference. They could have many reasons that don't have much to do with noise reduction. I.E. maybe people who have had T for over 5 years rate its intrusiveness lower, regardless of volume. And that would impact the study. I do not think this decision is based on a belief that it is less beneficial for people who have it a long time. I can ask though!

Ah good point. I didn't see that with the guidelines so that's interesting. Probably saw a different list so I'll have to check it out later.

For the curious, here's an official list of requirements needed to participate in the trial:
• Age (years) is greater than or equal to 18
• Constant, subjective, tinnitus for 6 months or longer without active ear infection
• Absence of Superior Canal Dehiscence
• Absence of unilateral or bilateral cochlear implant
• Absence of acoustic neuroma

https://umhealthresearch.org/#studies/HUM00143675
If you want to join, click "I'm interested"

 

[Ambassador]

Awesome! I don't know your age, but there is preference for people under 65 and with a shorter onset of T. But awesome either way!

I'm 64, tinnitus 4 years. I just make it, wonder if that's why I didn't get the call. Age discrimination I tell ya, LOL.
Honestly, these style therapies have been around for a long time, even this clinic has had it for years and I will remain hopeful but not holding my breath for any commercial products in my lifetime.

 

[kelpiemsp]

I'm 64, tinnitus 4 years. I just make it, wonder if that's why I didn't get the call. Age discrimination I tell ya, LOL.
Honestly, these style therapies have been around for a long time, even this clinic has had it for years and I will remain hopeful but not holding my breath for any commercial products in my lifetime.

I would guess it has to do with limited devices and the amount of time it takes just to program someone. I.E. it will be around 10-15 hours of time for me w/the researchers to program the machine. They probably only have one or two devices they are trying to cycle 50 people through. That is just a guess though!

 

[Mathew Gould]

Is this new trial supposed to work on everyone or just people with somatic tinnitus?? My tinnitus is caused by my misaligned neck and jaw and could make my tinnitus go up if I turned my neck a certain way in the beginning of my tinnitus (I'm now 10 months with tinnitus) Now I'm not so sure I can make my tinnitus go up or down if I move my neck or jaw, maybe a little.... I just clenched my jaw down hard and I got a louder tinnitus sound.

 

[Ambassador]

With such a small number of participants this device is years away.

Just to keep this all in perspective.

https://www.fda.gov/ForPatients/Approvals/Drugs/ucm405622.htm

 

[threefirefour]

With such a small number of participants this device is years away.

Just to keep this all in perspective.

https://www.fda.gov/ForPatients/Approvals/Drugs/ucm405622.htm

That's the approval time for devices is much shorter. Susan shores device is a class 2 so it's actually a matter of months, not years, for it to get approved.

 

[Mathew Gould]

That's the approval time for devices is much shorter. Susan shores device is a class 2 so it's actually a matter of months, not years, for it to get approved.

Is this device gonna work for people like us with TMJ, bad neck and jaw that caused tinnitus @threefirefour??

 

[threefirefour]

Is this device gonna work for people like us with TMJ, bad neck and jaw that caused tinnitus @threefirefour??

Apparently it does because the cause of tinnitus for us is still fusiform cells.

 

[threefirefour]

With such a small number of participants this device is years away.

Just to keep this all in perspective.

https://www.fda.gov/ForPatients/Approvals/Drugs/ucm405622.htm

Circling back to this comment, I think it would be helpful to post some statistics about FDA device clearance.

https://www.emergogroup.com/sites/default/files/emergo-fda-510k-data-analysis-2017.pdf

 

[Mathew Gould]

Circling back to this comment, I think it would be helpful to post some statistics about FDA device clearance.

https://www.emergogroup.com/sites/default/files/emergo-fda-510k-data-analysis-2017.pdf

Say this device gets cleared by Oct 1st 2018. Where are you gonna have to go to get treatment, like what facilities? Also how long after Oct 1st will the avg person start treatment?

 

[threefirefour]

Say this device gets cleared by Oct 1st 2018. Where are you gonna have to go to get treatment, like what facilities? Also how long after Oct 1st will the avg person start treatment?

They will probably have to see an audiologist. Also theoretically once they get cleared, they could sell it the next day. BUT it will take time to roll out, make deals with providers to get it in stores, etc.

 

[NoBigDeal]

So this device could be available in 2019 ?

 

[threefirefour]

So this device could be available in 2019 ?

Could be but not likely. That's when they expect FDA approval, but they have to find ways to sell it.

 

[Cal18]

Isn't the equipment being used in this study is already out in the field so just the protocol would have to be mimicked? I sent the study details to a doctor who performs electrical stimulation and qEEG brain mapping and asked him if he was able to figure out what they're doing. I'll report back here if he has anything to say about it. Someone like him would probably be the type of person to perform such a treatment when/if it becomes available.

 

[jay777]

should we not find out if it works first?

 

[Cal18]

should we not find out if it works first?

So far, it seems very promising and I think it's definitely worth trying even if it doesn't work for some people.

 

[threefirefour]

Isn't the equipment being used in this study is already out in the field so just the protocol would have to be mimicked? I sent the study details to a doctor who performs electrical stimulation and qEEG brain mapping and asked him if he was able to figure out what they're doing. I'll report back here if he has anything to say about it. Someone like him would probably be the type of person to perform such a treatment when/if it becomes available.

Awesome good luck

 

[jay777]

How long did it take for the 2 people who where cured of tinnitus before it returned?

 

[Anthonyr]

How long did it take for the 2 people who where cured of tinnitus before it returned?

The study had the participants use the device for 30 minutes a day for four weeks. Once the treatments ended, though, the patients' tinnitus returned within a week, on average.

https://www.ctvnews.ca/mobile/healt...reduce-constant-ringing-of-tinnitus-1.3746819

 

[Pero1234]

Does anyone know if this would only help when T is perceived as a pure tone, or also when it's more of a hiss?

Or are we still in the dark there?

 

[threefirefour]

How long did it take for the 2 people who where cured of tinnitus before it returned?

Here's a good chart explaining the progress (The top one is the one that actually matters)

Does anyone know if this would only help when T is perceived as a pure tone, or also when it's more of a hiss?

Or are we still in the dark there?

One of the users here who went said it helped his hissing tinnitus.

 

[jay777]

So if we take this study at face value it's temporarily cured 10% and the rest have had an average 12 dB reduction, is this not the biggest breakthrough in tinnitus history?

I know one thing, if I had been on that study my machine would have gone missing.

 

[ee9892]

So if we take this study at face value it's temporarily cured 10% and the rest have had an average 12 dB reduction, is this not the biggest breakthrough in tinnitus history?

I know one thing, if I had been on that study my machine would have gone missing.

Please be aware that its a small sample size. We should know more after this next phase starting in august.

Its nice to have hope though

 

[Hania]

I emailed them about multiple tone tinnitus and hyperacusis. This was their response.

 

[Apolonia]

I emailed them about multiple tone tinnitus and hyperacusis. This was their response.

View attachment 18542

I don't understand this answer... Can someone explain it to me?

 

[Jiri]

I don't understand this answer... Can someone explain it to me?

I think it was a misunderstanding. Hania probably does have a constant multitone tinnitus and Jenny simply thought it's not constant and thus cannot qualify.

 

[threefirefour]

I emailed them about multiple tone tinnitus and hyperacusis. This was their response.

View attachment 18542

Didn't notice that before but I like how the last tab is "How to make screenshots in Microsoft"

 

[kelpiemsp]

Isn't the equipment being used in this study is already out in the field so just the protocol would have to be mimicked? I sent the study details to a doctor who performs electrical stimulation and qEEG brain mapping and asked him if he was able to figure out what they're doing. I'll report back here if he has anything to say about it. Someone like him would probably be the type of person to perform such a treatment when/if it becomes available.

Yes and no! The patented or tightly held idea is the timing. I.E. they measure the difference in time it takes for auditory signals traveling to brain vs electrical, and then provide an offset in hopes to induce plasticity. I don't know what the margin of error is or anything like that but...the wrong timing may have unintended consequences.

 

[kelpiemsp]

I emailed them about multiple tone tinnitus and hyperacusis. This was their response.

View attachment 18542

I asked the question about multiple tones, since pitch matching is required. The people conducting the study said honestly it isn't that important since people (unless they are musicians) are pretty much all over the board attempting to match the frequency.

Hyperacusis is a disqualifier because they play sound into your ear canal.

I think there is way to much concern of "will it work for my T". T is as unique as we are. Our definitions are pretty arbitrary. In the end it will ultimately be a try a see approach.