New University of Michigan Tinnitus Discovery — Signal Timing

I "expressed interest" to get their emails. I don't actually plan on doing it. I live in California so it's too far.

Oh I'm sure they do. If you're local any help is appreciated.
I'm closer to Michigan 4 hrs ride. I was even thinking to rent out an apartment there if they select me or the 4 hrs ride... Will see. I need to get .A good reduction of this intrusive t.
 
I'm closer to Michigan 4 hrs ride. I was even thinking to rent out an apartment there if they select me or the 4 hrs ride... Will see. I need to get .A good reduction of this intrusive t.
If we can get to rent an apt there that could be a good idea.
 
Probably a $360 airfare for me, times two (my wife).

Then add transportation, room and board.

But with all that funding maybe they will provide refreshments? (put me down as chocolate chip pls)

I'd probably wind up being a control subject. haha

I'm so pessimistic it's awful.
You can get free parking compensation, that's what they are offering.
 
This link is worth a read as Susan Shore is quoted many times. There's many pathway of tinnitus and they all go the brain. One pathway, the mandibular complex says hello to the auditory nerve first, but strangely there may be no hearing loss. The auditory nerve has it's own destruction abilities.

Susan Shore pretty much has the rest of the field covered with neck muscles. She does not have the facial nerve, mandibular nerve, digastric muscle, occipital nerves, or facet joints covered. Also she does not have control on one's head bending, posture, clenching of teeth or dental. All of these mentions have great involvement with physical tinnitus according to a link that I gave yesterday. All neurologists on neuro discussion boards agree. When I can maintain proper treatment of the above, my tinnitus is almost gone. The problem is when I start using bad posture and head bending, my tinnitus come backs faster than turning up the volume on the TV.

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566901/#R60
 
She does not have the facial nerve, mandibular nerve, digastric muscle, occipital nerves, or facet joints covered. Also she does not have control on one's head bending, posture, clenching of teeth or dental.

I have an odd one: I can shut both my eyelids in a manner that makes a fluttering sound (this is probably normal I'm guessing). The odd thing is this also makes a soft ringing bell sound, mostly in my left ear.

Weird, but for me it's normal.
 
I have an odd one: I can shut both my eyelids in a manner that makes a fluttering sound (this is probably normal I'm guessing). The odd thing is this also makes a soft ringing bell sound, mostly in my left ear.

What you mention has been discussed in neuro case study discussions a few times. Neuros are all in the same park that the SCM - left sternocleidomastoid is responsible 40 -60% of the time. 10% possibility is the temporalis and like 20 other things for the remaining possibilities with the vagus nerve - I believe is at 3%. I remember reading that all are treatable. I believe that they said that tension combined with posture balance is the cause.

The University of Michigan device may be able to help with that.
 
@85dB T A partial correction needs to be made. It's both the vagus nerve and the left sternocleidomastoid most of the time. I check my notes because I can do the same. Place two fingers on the sternocleidomastoid muscle where the vagus nerve intervenes, then close your eyes. You can feel either the vague nerve or the left sternocleidomastoid move (not sure which) and tinnitus will increase for a second. See this link for location on the top left side.

I would think that the Susan Shore device can help with this.
https://www.wisegeek.com/what-is-the-vagus-nerve.htm

Gee, I can even do it by touching where the vagus nerve crosses the trapezius within the picture in this link.
 
@85dB T A partial correction needs to be made. It's both the vagus nerve and the left sternocleidomastoid most of the time. I check my notes because I can do the same. Place two fingers on the sternocleidomastoid muscle where the vagus nerve intervenes, then close your eyes. You can feel either the vague nerve or the left sternocleidomastoid move (not sure which) and tinnitus will increase for a second. See this link for location on the top left side.

I would think that the Susan Shore device can help with this.
https://www.wisegeek.com/what-is-the-vagus-nerve.htm
Clenching my neck the t gets louder or just another sound same as closing my eyes hard.
 
I told my wife that when I touch my vagus nerve as it crosses the sternocleidomastoid and trapezius my T will increase for a second when I close my eyes. My wife then said "Oh I forgot to tell you, but your neuro wants to check your vagus nerve again by doper." How nice.

@1000 That isn't a big deal, so don't worry, but be careful with extreme fast turning of neck for a few more months. The neck will adjust.
 
I told my wife that when I touch my vagus nerve as it crosses the sternocleidomastoid and trapezius my T will increase for a second when I close my eyes. My wife then said "Oh I forgot to tell you, but your neuro wants to check your vagus nerve again by doper." How nice.

@1000 That isn't a big deal, so don't worry, but be careful with extreme fast turning of neck for a few more months. The neck will adjust.
Thanks.

Vague nerves can get irritated and have inflammation, are they ways to find out that?
 
Vague nerves can get irritated and have inflammation, are they ways to find out that?
Any doper tech can check that in 2-3 minutes. A doper is just a small hand device that makes almost no noise, but wear a pair of foam ear plugs because the location is close to the ears. The doper looks and will move like the Susan Shore device. It's very gentle and it might temporary at least lower your T.
 
I told my wife that when I touch my vagus nerve as it crosses the sternocleidomastoid and trapezius my T will increase for a second when I close my eyes. My wife then said "Oh I forgot to tell you, but your neuro wants to check your vagus nerve again by doper." How nice.

@1000 That isn't a big deal, so don't worry, but be careful with extreme fast turning of neck for a few more months. The neck will adjust.

Ok so the neck tries to get into its original or best alignment over time? How long can this take?
 
Is there a trial underway?

EDIT:

So I found this on ClinicalTrials.gov:

https://clinicaltrials.gov/ct2/show/NCT03621735

Estimated Study Start Date : September 2018
Estimated Primary Completion Date : September 2022
Estimated Study Completion Date : January 2023​

So 2024 is in my opinion the best guess for the device to come to market. That is a long time to wait. But reading this fills me with a lot of hope.

https://labblog.uofmhealth.org/lab-report/first-test-specially-timed-signals-ease-tinnitus-symptoms

"Overall, the loudness of phantom sounds decreased only after the actual, or bimodal, treatment, but not the sham treatment of sound only. For some, the decrease was around 12 decibels, about the equivalent of making it half as loud. Two participants said their tinnitus disappeared."

"We're definitely encouraged by these results, but we need to optimize the length of treatments, identify which subgroups of patients may benefit most, and determine if this approach works in patients who have nonsomatic forms of the condition that can't be modulated by head and neck maneuvers," says Shore.​
 
Is there a trial underway?

EDIT:

So I found this on ClinicalTrials.gov:

https://clinicaltrials.gov/ct2/show/NCT03621735

Estimated Study Start Date : September 2018
Estimated Primary Completion Date : September 2022
Estimated Study Completion Date : January 2023​

So 2024 is in my opinion the best guess for the device to come to market. That is a long time to wait. But reading this fills me with a lot of hope.

https://labblog.uofmhealth.org/lab-report/first-test-specially-timed-signals-ease-tinnitus-symptoms

"Overall, the loudness of phantom sounds decreased only after the actual, or bimodal, treatment, but not the sham treatment of sound only. For some, the decrease was around 12 decibels, about the equivalent of making it half as loud. Two participants said their tinnitus disappeared."

"We're definitely encouraged by these results, but we need to optimize the length of treatments, identify which subgroups of patients may benefit most, and determine if this approach works in patients who have nonsomatic forms of the condition that can't be modulated by head and neck maneuvers," says Shore.​
I really hope that the study doesn't have to complete or that there is some sort of mistake here. This is a complete month ruiner.
 
The study has two sections, 6 weeks active and 6 weeks sham. The assessment is from baseline and up to 38 weeks from treatment, so it seems they are going to follow up a while after to measure any lasting effects.

The completion date may well be the date they expect to have fully analysed the data. It may be that they will build a PhD around the analysis and the timing allows for this.

The impending release of the Neuromod device may well push things forward as fast as we would like to see it. And there will also be other players watching from the sidelines who have their own bi-modal products in the making. I see it a bit like the race to put someone on the moon.
 
Estimated Study Start Date : September 2018
Estimated Primary Completion Date : September 2022
Estimated Study Completion Date : January 2023
So 2024 is in my opinion the best guess for the device to come to market.
I really don't know if I can hold on for that long. And I know this sounds very hypocritical of me as I have told other people that those devices and other treatments are worth waiting for but another potential 5-6 years without any relief... 2-3 years, okay, but losing another 5 years or even more... I really don't want to think about it.
 
Per the ATA podcast with Dr. Susan Shore from this July, results are expected from the current trial by the end of 2019 and depending on the results, commercialization efforts would follow.

https://www.ata.org/podcasts/episode-7-breakthrough-using-multisensory-stimulation-reduce-tinnitus
I just sent an e-mail to Dr. Shore asking her about bringing her device to market and the timeframe for that. Seems in the light that the clinicaltrials.gov site says an estimate of 2023 for full completion and the interview says, like you pointed out, that if all goes well with the study, they would begin the process of bringing the device to market at the end of 2019.
 
I got an answer to my questions from Dr. Shore.

"It is possible that it will come to market before, but this is still in progress and depends on many factors. We are trying our best."​

So there it is we need to give them time and hope for the best. It is a very hard pill to swallow but we have never been this close to silence before with real science backing it up as we are right now.
 
I got an answer to my questions from Dr. Shore.

"It is possible that it will come to market before, but this is still in progress and depends on many factors. We are trying our best."​

So there it is we need to give them time and hope for the best. It is a very hard pill to swallow but we have never been this close to silence before with real science backing it up as we are right now.
How can you get a reply in 15 minutes but it takes days, if it ever happens for me?
 

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