Nicergoline / Sermion?

[teacher34]

Does anyone know how to get Nicergoline (brand name is Sermion)? It isn't available in the US yet, as the FDA hasn't approved it. I've begun to really dislike the FDA as I've been on my search for effective treatments...

Is it available in Canada? Does anyone know if Americans with a valid prescription can travel to Canada and have the medication filled there?

Has anyone here been helped by Nicergoline/Sermion?

 

[JohnAdams]

I've begun to really dislike the FDA

There are some FDA officials that make me totally understand the necessity of an eternal burning lake of fiery punishment.

 

[Bill Bauer]

Is it available in Canada?

It is listed in
https://www.drugbank.ca/drugs/DB00699
which is a Canadian website. Not sure whether this means that it is available in Canada.

Does anyone know if Americans with a valid prescription can travel to Canada and have the medication filled there?

Google the word "pharmacy" and the name of the Canadian city closest to you. The search results ought to provide you with a number of drug stores and their phone numbers. Call one or two of these pharmacies and ask your question. I am 99% sure that their policy is to Not fill those American prescriptions (I believe I already called a pharmacy in my town on behalf of my mom's American friend), but you will want to double check.

 

[DebInAustralia]

Does anyone know how to get Nicergoline (brand name is Sermion)? It isn't available in the US yet, as the FDA hasn't approved it. I've begun to really dislike the FDA as I've been on my search for effective treatments...

Is it available in Canada? Does anyone know if Americans with a valid prescription can travel to Canada and have the medication filled there?

Has anyone here been helped by Nicergoline/Sermion?

Just curious as to why you are considering sermion?

are you thinking your t is a perfusion issue?

 

[teacher34]

Just curious as to why you are considering sermion?

are you thinking your t is a perfusion issue?

I'm considering it because it's been reported to help some people.

 

[teacher34]

There are some FDA officials that make me totally understand the necessity of an eternal burning lake of fiery punishment.

They had no problem approving the med that helped cause my tinnitus, but the med that might help treat it? Noooo...

 

[DebInAustralia]

They had no problem approving the med that helped cause my tinnitus, but the med that might help treat it? Noooo...

Which med caused your t?

 

[teacher34]

Which med caused your t?

Megadose ibuprofin prescribed by a podiatrist and promised to be totally safe. Not.

 

[Frédéric]

Effectiveness of Nicergoline in Preventing Acoustic Trauma

Abstract

Background: In Thailand, military personnel attending the annual firing practice are at risk for acoustic trauma (AT). Presently, hearing protection devices have been approved to prevent AT. Furthermore, N-acetyl-cysteine or magnesium were proved to be beneficial for hearing protective effect. However, the study of the effectiveness of nicergoline on preventing AT is limited. The study aimed to demonstrate the effectiveness of nicergoline in preventing AT.

Methods: The study employed a randomized controlled trial design. Two hundred twenty-four participants were evaluated for general physical status, hearing threshold level and blood chemistry. The inform consent form was explained and signed, and participants were allocated to 2 groups. The study group (n=118) was prescribed nicergoline 30 mg twice daily for 2 weeks before the firing practice and 1 week after firing practice while the controlled group (n=106) was prescribed placebo. All participants had to wear the silicone ear plugs. The postfiring practice audiograms were measured within 48 hours. Aural symptoms (tinnitus and aural fullness) and the side effects of the medication were also recorded.

Results: The incidence of AT was detected in 14 ears, 10 ears from the placebo group ( p =0.075). The postfiring practice audiograms showed the average hearing threshold level of the study group significantly improved than that of the control group across all frequencies ( p <0.05). Moreover, the audiograms from the placebo group worsened at 250Hz and 6,000 Hz ( p <0.05). The presence of tinnitus and aural fullness in the study group occurred over a shorter period than that in the placebo group.

Conclusion: The incidence of AT occurred in both groups. The effectiveness of nicergoline from this study demonstrated reduced tinnitus after firing practice. Furthermore, the hearing threshold significantly improved in the study group.

Source: https://europepmc.org/article/ppr/ppr174971