Recent Chinese Study on Spontaneous Decrease in Tinnitus

[PDodge]

This thread gives me hope!

 

[Jason37]

Our redemption from this may be at hand. We must endeavor, no matter how insignificant our efforts may seem, to remove every useless barrier to obtaining a cure for this that we can.

I like your optimism....but we just don't know what will happen with human subjects at this point. I was in this trial at the end of summer in San Antonio and decided to leave it after my physical and 1st consult. I was made aware that there is a risk that there could be hearing loss caused by the mechanical changes in the inner ear....or hopefully nothing will happen except positive cell growth.

I just did not want to risk it at this time. Also they are still figuring out the dosage and there is the possibility that there would only be partial growth without an established standard.

But I can tell you I spoke to doctor Rosenblume personally and the 4 patients before me had tolerated everything well.

I asked him if their hearing was restored and all he would say is "Things are on track".

 

[JohnAdams]

Things are on track

Of course they are.
The proof or concept is there. The preclinical data is very positive. Tinnitus from NIHL is obviously from hair cell death. All signs point to success.
Ive been shocked by high voltage and my nerves didnt create a phantom limb sensation in my fingers. Stupid people are speculating noise induced tinnitus is from nerve damage all the way to brain damage. It's all bullshit. The only element that doesnt heal in this system is the hair cells and their ribbon synapses. FX-322 fixes this.

I'm 99% sure that this is the path forward. Fuck the FDA, they should have no part in this. They have an investment banker as their leader. They are just slowing down the development of this drug and inflating the cost of it. We need this type of technology now.

 

[Don Tinny]

@Telis
Your case is very similar to mine. I notice that whenever the tinnitus returns it does worse than before. I wonder why. I think that the brain finds new and also old hearing loss again.

 

[Telis]

@Telis
Your case is very similar to mine. I notice that whenever the tinnitus returns it does worse than before. I wonder why. I think that the brain finds new and also old hearing loss again.

Yeah, I've considered this, I think whatever improvement that I had the last time has kind of been reignited after the recent acoustic trauma, plus whatever new damage has been done. This time I notice that my hearing is really bad, the hearing loss is bothering me a lot, external noise is tin sounding and distorted. Watching TV is painful in the sense that it's just a bunch of distorted noise, plus my tinnitus, very exhausting, really hope the brain can recognize better than it's done so far.

 

[Telis]

Of course they are.
The proof or concept is there. The preclinical data is very positive. Tinnitus from NIHL is obviously from hair cell death. All signs point to success.
Ive been shocked by high voltage and my nerves didnt create a phantom limb sensation in my fingers. Stupid people are speculating noise induced tinnitus is from nerve damage all the way to brain damage. It's all bullshit. The only element that doesnt heal in this system is the hair cells and their ribbon synapses. FX-322 fixes this.

I'm 99% sure that this is the path forward. Fuck the FDA, they should have no part in this. They have an investment banker as their leader. They are just slowing down the development of this drug and inflating the cost of it. We need this type of technology now.

John, you seem like a bit of a wild man, I like it.

 

[JohnAdams]

John, you seem like a bit of a wild man, I like it.

Thanks.

 

[Kratos]

Yeah 120db rattling through your skull in a small enclosed space is just not a good idea, even if you don't have tinnitus. Not sure what I was thinking.

Did you wear hearing protection?

 

[Telis]

Did you wear hearing protection?

Yeah I did, 32 dB foam, that I'm sure wasn't inserted correctly. Everyone that I have talked to, used muffs and plugs. It was loud as hell, even with the plugs in. When I got out I knew I was screwed, my ears were full, and I could barely hear the tech

 

[Tom Cnyc]

Yeah something healed, it took ages but it happened. I got too confident after that. If I were in that mri a couple of years ago, I would have stopped it. But having that improvement made me overly confident, now I'm screwed again, but worse. I don't know, maybe I threw my second chance away, but trying to keep positive. I can't even sleep this time around, I'm hoping it can't stay like this, it's not livable.

I think it will fade again for you. Do yourself a favor though. Go get custom molded silicon earplugs. It's the best money you'll ever spend, and you'll never have to worry about improper insertion ever again.

 

[Laurie1961]

Five years, huh? I still have tinnitus. It began in 2009.

 

[BrianW.]

Might be due to MSG and you are having a increased glutamate reaction.

Hi Jack,

Would you say that caffeine, sugar and NSAIDs truly lead to tinnitus worsening? Or high blood pressure?

This is the wisdom from many online sites like WebMD - but I hope to know what everyone else thinks.

 

[GBB]

This is interesting because it is saying cochlear healing needs to lead tinnitus healing times by potentially a significant margin, and yet we can do things to the cochlea like shining a laser on it, which cause an immediate spike, as anyone here who has done LLLT can attest. My question is, why are spikes etc... instantaneous while recovery is a lagging process. I really am curious, not just bitter.

 

[tommyd87]

This is interesting because it is saying cochlear healing needs to lead tinnitus healing times by potentially a significant margin, and yet we can do things to the cochlea like shining a laser on it, which cause an immediate spike, as anyone here who has done LLLT can attest. My question is, why are spikes etc... instantaneous while recovery is a lagging process. I really am curious, not just bitter.

I might be wrong but I'm interpreting this as saying that there might be a gap between when your hearing is restored and when the tinnitus goes away. At this stage I wonder whether we would have such an experience as the ears and then the brain need to pick up and also really recognise that there is more regular input into the ears.

 

[xyz]

My question is, why are spikes etc... instantaneous while recovery is a lagging process. I really am curious, not just bitter.

Probably because it's much easier to break something than to build it.

 

[GBB]

I might be wrong but I'm interpreting this as saying that there might be a gap between when your hearing is restored and when the tinnitus goes away. At this stage I wonder whether we would have such an experience as the ears and then the brain need to pick up and also really recognise that there is more regular input into the ears.

I agree - I imagine any regenerative medicine will need to follow the same pattern where a "recalibration" period occurs in the brain. I just think it's interesting spikes can be instantaneous whereas new valid input takes time to be picked up, so to speak.

 

[tommyd87]

I agree - I imagine any regenerative medicine will need to follow the same pattern where a "recalibration" period occurs in the brain. I just think it's interesting spikes can be instantaneous whereas new valid input takes time to be picked up, so to speak.

So do I although I think there are two things that can be looked at with recalibration that may explain something about this theory.

Firstly, the medicine takes time to work and as a result it is simply not going to fix it instantly. So subsequently you will have a delayed stabilising effect.

Secondly, I hope that we get a better understanding of this theory through the hopefully successful regenerative medicine.

 

[Sironketchup]

I do not believe real tinnitus has much of spontaneous recovery.
Real tinnitus is a chronic condition.
If it goes away maybe it was extended fleeting tinnitus or so, lol...

 

[tommyd87]

I do not believe real tinnitus has much of spontaneous recovery.
Real tinnitus is a chronic condition.
If it goes away maybe it was extended fleeting tinnitus or so, lol...

I think that tinnitus tends to be directly linked to auditory deficiencies. Thus repairing these auditory deficiencies such as busted synapses will alleviate tinnitus.