I'm on Diamox and it has not changed my loud screeching 24/7 tinnitus from 2 years ago and counting. It did help to relieve other things in the ears, the crackling and pressure from endolymphatic hydrops. I was hoping that the relief of the hydrops would lower the tinnitus, but it has not. My tinnitus was from an MVA, and I have all sorts of jaw/neck/ear/head injuries. The level of tinnitus I have is high metallic loud constant screeching. I'm trying to hold onto my sanity, but some days, it is very difficult. I'm thankful for everyone sharing their experiences.