also, could someone tell me how to quote someone in a post? Thanks in advance
Click the "quote" button on the lower right of the posting box.
also, could someone tell me how to quote someone in a post? Thanks in advance
If you look at the pipeline page on their web site, SP-5557 seems to be the drug candidate for regeneration. They say they are looking at an IND filing in the fourth quarter 2017. (Looking around, it has been in the pre-clinical stage since at least 2009...) If that is accepted, then they will start phase 1 trials sometime after that. Of course that drug is targeted at people with severe to profound hearing loss. They have other drugs that are farther along for other indications.So, are there any release dates on this? Have they put any messages out on how many DB's this may bring back?
I think this is different than the trial Aaron were talking about for Ménière's Disease ?I missed (and nothing was published on this forum) this phase 2 trial entitled:
Otoprotection With SPI-1005 for Prevention of Temporary Auditory Threshold Shift
https://clinicaltrials.gov/show/NCT01444846
Although, it is listed in the company website pipeline:
https://soundpharma.com/pipeline/
However sadly, tinnitus is only listed as a possible condition, but not as a secondary outcome (improvement or not).
Results:
http://www.thelancet.com/journals/lancet/article/PIIS0140-6736(17)31791-9/fulltext
@Aaron123 : thanks for the source (prnews article)
Someone stated that this was an ear and brain disease. What if the difference between the acute and chronic phases are that the tinnitus moves from the ear into the brain and it settles there. And that is the difference between these.
Tinnitus starts out in auditory regions of the brain and then spreads to other regions of the brain.That's not how tinnitus works. Damage to the ear has virtually immediate effects on the brain. The perception of tinnitus -whether acute or chronic- obligatory involves the brain, though does not always involve the ear.
Tinnitus starts out in auditory regions of the brain and then spreads to other regions of the brain.
This is where the mystery arises.
This thread had been trending since 2012. I can see why you feel this way!!If I were to compare myself last year during this time and now, it is like sky and earth in every sense. I feel always tired now, forgetful, tired, etc.
Hopefully they can use this on tinnitus alone.
Hopefully they can use this on tinnitus alone.
I'm with you. As much as I'd like my hearing back stop the tinnitus!Hopefully they can use this on tinnitus alone.
"SPI-1005 is given orally and is being tested in several neurotologic indications including noise induced hearing loss and tinnitus,..."Good news for Ménière sufferers:
https://www.biospace.com/article/re...i-1005-in-the-treatment-of-meniere-s-disease/
Good news for Ménière sufferers:
https://www.biospace.com/article/re...i-1005-in-the-treatment-of-meniere-s-disease/
So how many more trials do they need?"SPI-1005 is given orally and is being tested in several neurotologic indications including noise induced hearing loss and tinnitus,..."
It would seem it could help sufferers like myself with NIHL and tinnitus. Very very exciting.