All the patients who were administered the anti-coagulant "have shown evident abatement of the tinnitus symptom." http://www.ncbi.nlm.nih.gov/pubmed/15106284
Study of Anticoagulant Sodium Enoxaparin
- Thread starter HighDesertSage
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SoulStation
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Abatement can just mean lessening and they didn't say how they measured the results(i.e. MML, TFI).
But who knows. I'm down to try anything that will work. If this medication did work miracles it's either a diamond that the whole tinnitus suffering world has overlooked or a failure. This reminds of part of why I think the reason thats everybody is so crazy about the "Retigabine thread"(with the obvious exception of the threads author having almost complete cessation) is that it's a medication that has shown promise with a decent theory which hasn't been effectively studied (and shown to fail) in a proper double-blind trial.
Here's a little more information on further related studies: http://www.tinnitusformula.com/library/sodium-enoxaparin-for-the-treatment-of-tinnitus/#.VFZ4d_nF9rk
SoulStation
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It's odd that the link is an add for Ginko since Ginko is not what's discussed in the study. I'm not really buying the argument that since both benefit capillary circulation, results for one can support use of the other.
May add this to my suggestion to my new doc about things we can try.
May add this to my suggestion to my new doc about things we can try.
I agree with rtwombly that this study does not directly support the use of Ginko. However, Barry Keate is quite knowledgeable about tinnitus and its treatment. Unfortunately, both reported studies of sodium enoxaparin are quite small, and dealt with a select group of patients. BTW, this substance is a low molecular weight heparin product - a highly effective anticoagulant. The studies suggest to me that these particular tinnitus victims suffered from an impairment of their micro-circulations, perhaps as an auto-immune phenomenon (those with Lupus) or other vascular problems. It appears unlikely that those who suffer from tinnitus secondary to hair-cell damage (such as from noise exposure) or tinnitus secondary to acoustic nerve degeneration would experience similar benefits. Also, extended treatment with enoxaparin carries significant risks associated with the diminished ability for one's blood to coagulate. Such treatment must be carefully controlled and observed.
