Susanna Pietropaolo — Ion Channels in Tinnitus and Hyperacusis

[Nick47]

Project status: active

At the Aquitaine Institute of Cognitive and Integrative Neuroscience in Pessac (France), Susanna Pietropaolo is attempting to find a treatment for hyperacusis and tinnitus, abnormalities of auditory perception that can be severely debilitating in everyday life.

Susanna Pietropaolo - Identifying Novel Molecules to Treat Hyperacusis and Tinnitus

It's basically a 3-year grant looking at Potassium Ion channels. The project started in October 2020.

 

[Brian Newman]

Nice to know there's more research being done.

 

[stacey]

Wow, I hope this isn't false hope :/ I've given up.

 

[Nick47]

Publication on Calcium activated potassium channels in Fragile X Syndrome.

Hyperacusis in the Adult Fmr1-KO Mouse Model of Fragile X Syndrome: The Therapeutic Relevance of Cochlear Alterations and BKCa Channels

 

[ErikaS]

Publication on Calcium activated potassium channels in Fragile X Syndrome.

Hyperacusis in the Adult Fmr1-KO Mouse Model of Fragile X Syndrome: The Therapeutic Relevance of Cochlear Alterations and BKCa Channels

Soo does this make Chlorzoxazone relevant to medications to try if one is experiencing reactivity and/or hyperacusis? I am aware they did an acute intervention via injection so the effects are based off of that acute treatment, but wondering if it's worth a shot orally.