Water-Soluble Coenzyme Q10 in Chronic Hearing Loss

[Tigo]

Water-Soluble Coenzyme Q10 in Chronic Hearing Loss

https://doi.org/10.1177/0194599811416318a202

Abstract
Objective: Q-TER is a multicomposite water-soluble formulation of CoQ10; in particular, Q-TER consists of a mixture of maltodextrin, acting as a carrier, of CoQ10 molecules of sucrester, which serves as bioactivator. The purpose of this study was to evaluate the efficiency of Q-TER in subjects with chronic sensorineural hearing loss.

Method: A total of 80 patients affected by chronic sensorineural hearing loss were included. The patients were divided, at random, into 2 numerically equal groups (A and B). Group A underwent therapy with Q-TER, 160 mg, once a day for 30 days; group B received placebo, once a day for 30 days.

Results: Before, at the end, and 6 months after the end of the treatment, all patients underwent: pure tone audiometry, transient evoked otoacoustic emissions (TEAOE) and otoacoustic products of distortion (DPOAE), auditory brainstem response and speech audiometry. Compared with group B, at the end of the treatment in group A the pure tone audiometry showed a significant (P < .05) improvement of the audiometric thresholds at the 1.000, 2.000, 4.000, and 8.000 Hz. This improvement was confirmed by the data obtained with the speech audiometry and in the last check. We found no significant differences in the others parameters and in group B.

Conclusion: It is quite early to be enthusiastic. There must be more studies with controlled results. However, this kind of therapy for chronic hearing loss seems to be interesting, especially to stop hearing decay. It is also remarkable that good results are found one month after the beginning of the treatment.

 

[another sean]

This was done 9 years ago.

https://www.ncbi.nlm.nih.gov/pubmed/20443731

 

[Tigo]

But ... are there members here that can confirm that Co-Q10 was helpful?

 

[Mister Muso]

But ... are there members here that can confirm that Co-Q10 was helpful?

Co-Q10 is one of the many ingredients in Neurozan which I've been taking mainly for the Ginkgo. Tinnitus and hyperacusis seem much improved. Also taking omega oils, NAC and B complex vitamins.

https://www.vitabiotics.com/products/neurozan-original

 

[Chriscom]

Co-Q10 is one of the many ingredients in Neurozan which I've been taking mainly for the Ginkgo. Tinnitus and hyperacusis seem much improved. Also taking omega oils, NAC and B complex vitamins.

https://www.vitabiotics.com/products/neurozan-original

FWIW, I've been taking Co-Q10 for at least five years now, predating my sensorineural hearing loss by about 4 1/2 years. My hearing certainly hasn't rebounded.

 

[d'Wooluf]

You read something like that and you think... Bingo! And then you find out it was done 9 years ago. So you'd expect to see some critical analysis of the experimental design published since then, or you'd expect to see further studies trying to replicate those results. But nothing. It just sits there. Now even if the overall shift in thresholds wasn't great (and we don't know) it still means that for those people in the control group, their hearing was better than it would have been without the supplement. So this could be important and you'd expect something to happen! But no. Silence.

I've started taking Q10. I have a number of issues that *may* benefit, so why not? I found a few studies that indicated possible benefit for hearing. The one I recall showed likely benefit in facilitating recovery from noise trauma. Still, I'm not expecting miracles. Maybe slowdown of further hearing loss.

The question remains why isn't this stuff pursued and settled one way or the other?

 

[GORYLUCK]

You read something like that and you think... Bingo! And then you find out it was done 9 years ago. So you'd expect to see some critical analysis of the experimental design published since then, or you'd expect to see further studies trying to replicate those results. But nothing. It just sits there. Now even if the overall shift in thresholds wasn't great (and we don't know) it still means that for those people in the control group, their hearing was better than it would have been without the supplement. So this could be important and you'd expect something to happen! But no. Silence.

I've started taking Q10. I have a number of issues that *may* benefit, so why not? I found a few studies that indicated possible benefit for hearing. The one I recall showed likely benefit in facilitating recovery from noise trauma. Still, I'm not expecting miracles. Maybe slowdown of further hearing loss.

The question remains why isn't this stuff pursued and settled one way or the other?

Well who's guna wanna spend any money on researching it further.... Not a drug company
I do notice this is a special water soluble formulation.... CoQ10 is usually fat soluble so maybe it has a harder time of getting into the cochlea...... whereas a water soluble kind might just slip on in there.... AHA
I mean some substances get in there... hmmm like ototoxic substances.... and NAC .........

 

[ChrisBoyMonkey]

Co-Q10 is one of the many ingredients in Neurozan which I've been taking mainly for the Ginkgo. Tinnitus and hyperacusis seem much improved. Also taking omega oils, NAC and B complex vitamins.

https://www.vitabiotics.com/products/neurozan-original

Just bought this on Amazon upon your anecdotal reported success. Worth a shot for 11 bucks.

 

[Mister Muso]

Just bought this on Amazon upon your anecdotal reported success. Worth a shot for 11 bucks.

Hope it does something for you. It's always difficult to be sure exactly what it is that's helping or hindering progress, but I've read lots about gingko on the forum which is the main ingredient.

 

[Chriscom]

Hope it does something for you. It's always difficult to be sure exactly what it is that's helping or hindering progress, but I've read lots about gingko on the forum which is the main ingredient.

I've been taking Co-Q10 daily for at least five years, four and a half of which I had normal hearing. I suffered hearing loss and acquired tinnitus back in May and I can't say my hearing has rebounded since then!

 

[MRItechssuck]

Co-Q10 is one of the many ingredients in Neurozan which I've been taking mainly for the Ginkgo. Tinnitus and hyperacusis seem much improved. Also taking omega oils, NAC and B complex vitamins.

I thought Ginkgo Biloba was debunked years ago for tinnitus?

 

[Mister Muso]

I thought Ginkgo Biloba was debunked years ago for tinnitus?

Maybe but does it sometimes depend on the cause of t, dosage levels etc? And what about hyperacusis which can be a bigger issue for me.

I'm afraid I dont have the time to read all the threads and research articles that I would like. That Neurozan product does contain a number of potentially useful supplements. Not a very scientific approach I know, but I'm always happy to be given more information.