Recent content by dd314

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    Perilymph Fistula (PLF) — Anyone Had Surgery?

    Every source on the internet says that a CT scan can absolutely detect a fistula. Keep in mind that the cochlea is a macroscopic structure—you can see it with the naked eye. It is about a quarter of an inch in diameter.
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    LL-341070 Remyelination

    I used to believe this but I'm not so sure anymore. There was a wildly successful tDCS study last year which gave people a -30 TFI score and I'm sure it entails actual volume reduction. tDCS only affects the cortex, which is the outer layer of the brain; it doesn't even affect deeper...
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    Frequency Therapeutics — FX-345

    I lost a ton of money on FREQ as well. If I recall correctly, the placebo group showed unprecedented improvements, which likely means some participants were dishonest about their scores. However, there's no reason to suspect any deceit on the company's part—they genuinely believed their product...
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    Abraham Shulman Tinnitus Protocol (Clonazepam Plus Gabapentin)

    You might want to look into Tofisopam. From what I’ve researched, it seems to have one of the best efficacy-to-side-effect ratios among available drugs. Some people report that it reduces their tinnitus by half. Plus, since it doesn’t act on GABA receptors, it’s associated with minimal tolerance...
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    New University of Michigan Tinnitus Discovery — Signal Timing

    Lenire and Auricle operate in different ways. Lenire works by increasing hyperactivity in the dorsal cochlear nucleus (DCN) to distract the brain from tinnitus. In contrast, Auricle reduces hyperactivity, aiming to address the underlying issue directly.
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    New University of Michigan Tinnitus Discovery — Signal Timing

    I've been out of the loop on this for a while. What do we think now? 2030? 2050?
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    Wish there were more Tofisopam reports, seems like the promising drug for tinnitus

    Wish there were more Tofisopam reports, seems like the promising drug for tinnitus
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    My other health issues are worsening my tinnitus. UGH.

    My other health issues are worsening my tinnitus. UGH.
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    Hearing Aids

    Residual inhibition is real. If you could boost low-decibel noises whilst not boosting loud noises -- maybe having a cutoff around 55 dB, it could theoretically work to suppress tinnitus. I'd probably be scared of it accidentally boosting loud noises, though. That would have horrific consequences.
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    If You Must Get an MRI, Would You Opt for Full Sedation?

    Some machines are noisier than others. I had to take Valium to avoid a panic attack, but I wouldn’t call the experience traumatic—just panic-inducing. The Siemens Aera with Quiet Suite is genuinely pretty quiet when used with tightly inserted foam earplugs and headphones on top. I recommend the...
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    Droning Pressure Attacks: Ménière's, or Noise-Induced Tinnitus?

    It happened again today. I am certain it is something of cochlear origin—there is no way it is just in the brain. I have dysautonomia, so I have attributed it to either vasospasm or vasoconstriction in the inner ear, or perhaps fluid pressure buildup, similar to what occurs in hydrops. I cannot...
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    New University of Michigan Tinnitus Discovery — Signal Timing

    It's marginally off-topic, but the entire FDA is getting gutted, apparently. The last time Trump was in office, he cut a tremendous amount of red tape within the FDA. Regardless of your politics, this should be good for us, right?
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    New University of Michigan Tinnitus Discovery — Signal Timing

    She speculated that it might work for both in the Q&A. Technically you can't ask a guinea pig if it has somatic tinnitus, then again you can't ask if your tinnitus machine worked either.
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    Here's a Safe Benzo Drug for Tinnitus Sufferers: Tofisopam (Emandaxin, Grandaxin, Sériel)

    Apparently, Tofisopam can cause tinnitus as its sole withdrawal symptom. How perfect for us. Source: A Comparison of the Anxiolytic Properties of Tofisopam and Diazepam: A Double-Blind, Randomized, Crossover, Placebo-Controlled Pilot Study
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    Droning Pressure Attacks: Ménière's, or Noise-Induced Tinnitus?

    Ugh. This just happened again, and it’s so scary. I really hope it’s benign.