Recent content by Gorbeh3

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    Sound Pharmaceuticals (SPI-5557 & SPI-1005)

    I disagree. Of course, you need to keep a rational, grounded outlook. None of us here will be cured in the next 5 years, but every step gets us closer to our destination.
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    Inner Ear Hair Cell Regeneration — Maybe We Can Know More

    I’m not sure what you mean by this. Do you mean acquired hearing loss? Doesn’t this simply mean that the individual lost their hearing after birth?
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    Inner Ear Hair Cell Regeneration — Maybe We Can Know More

    I’m not entirely sure I understand this. Hypothetically, if someone has hearing loss where 50% is attributed to genetics and the other 50% to noise exposure, and assuming the drug works perfectly, does that mean it can only restore 50% of the lost hearing capability? What other types of...
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    Inner Ear Hair Cell Regeneration — Maybe We Can Know More

    You know what else hurts? I still think FX-322 wasn’t a complete failure, they just needed more time and research but unfortunately ran out of cash. *sigh* hang in there dudes. One day...
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    Frequency Therapeutics — Hearing Loss Regeneration

    TL;DR: 2023 is do or die for Frequency Therapeutics. There is something here but the results haven't been as consistent as desired and there are a ton of questions remaining. They only have $111M left in cash and operating expense were $98M last year. If it doesn't see strong enough results to...
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    Frequency Therapeutics — Hearing Loss Regeneration

    Scientists from King’s College London, the Karolinska Institute, and Erasmus University have recently discovered ten additional genes connected to hearing loss, and located the part of the ear affected. The results, which were published in the American Journal of Human Genetics on May 16th...
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    Frequency Therapeutics — Hearing Loss Regeneration

    Does anyone have insight on the state of Frequency Therapeutics right now? I have been seeing a lot of new articles out there but no new information, possibly suggests they are on a media campaign to try to revive a company in decay. I also heard rumors they had to lay off a bunch of staff...
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    Frequency Therapeutics — Hearing Loss Regeneration

    Summary of this morning's presentation: Encouraging results and they seem to have something here and be on the right path, but it is not a "golden ticket" at this time, there is much more work to be done but there is justification to be optimistic. One of the biggest hurdles is delivery of the...
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    Frequency Therapeutics — Hearing Loss Regeneration

    More information --> Additional information link https://www.clarahealth.com/studies/hearing-study Another thing Exclusion Criteria: Evidence of or previous diagnosis of auditory neuropathy, traumatic brain injury, "central" hearing loss, or "genetic hearing loss". Is that not incredibly...
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    Frequency Therapeutics — Hearing Loss Regeneration

    Clinical Study Sites New York, New York New York, New York (Actually NJ) Albany, New York Amherst, New York Richmond, Virginia Norfolk, Virginia Winston Salem, North Carolina Novi, Michigan Cincinnati, Ohio Orangeburg, South Carolina Charleston, South Carolina Milwaukee, Wisconsin St. Louis...
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    Frequency Therapeutics — Hearing Loss Regeneration

    Exclusion Criteria: 1. Subject has previously been randomized in a FX-322 clinical trial. Conflicting information?
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    Frequency Therapeutics — Hearing Loss Regeneration

    Anyone watch the presentation this morning? Can anyone give a summary? Anything new?
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    Frequency Therapeutics — Hearing Loss Regeneration

    Noise-induced hearing loss Age-related hearing loss Antibiotic related hearing loss (ototoxicity?) Viral/bacterial related hearing loss Congenital hearing loss (genetic?) Other types of hearing loss? What are the odds that FX-322 works for some but not for others?
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    Frequency Therapeutics — Hearing Loss Regeneration

    I just want to throw this out there. I had probed into the Phase 2 clinical trials and the following came up: - "The trial was looking specifically for people who had significant dips at 4 kHz to 8 kHz on their audiogram. They did not say if a specific baseline was required for frequencies...