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The link provided by @RODRIGO does not work anymore, but here is a related publication.

Weird thing: on this website from a French practitioner, hyperacusis and tinnitus are listed as exclusion criteria: https://www.lartdesecomprendre.com/conseils-et-contre-indications/

Can Pupillometry Help to Choose the Right Nerve for Tinnitus Reduction? Once again, a new article from researcher Henk Koning. I really do not understand his research. Maybe someone can explain it to me?

Work absence and ability in tinnitus patients: the role of hyperacusis and tinnitus severity

It is always the same dilemma. Is it useful or harmful to post this kind of publication? I personally think it is useful to keep awareness of our torment, even if it has already been said, but it is up to the moderators. Systematic review and meta-analysis of the correlation between tinnitus...

The important information is this: A U-shaped relationship between sleep duration and tinnitus incidence: analysis of 13,871 participants from NHANES

Plasticity of the auditory cortex and brainstem in surgically induced unilaterally deaf adult humans with and without tinnitus Highlights The unilaterally deaf (UD) with tinnitus group showed high ipsilateral hemisphere cortical auditory evoked potential amplitude. This increased sensor level...

The PDF publication below reminded me of this thread. By the way, searching otolithlabs.com with the keyword tinnitus returns “no results found.”

Yet another team is trying to solve the inner ear delivery issue. Injectable polyplex-loaded glycol chitosan thermogel for efficient and safe inner ear gene delivery Highlights A novel RH-PAMAM G2 polyplex-loaded HGC thermogel system has been designed to enable effective gene delivery to the...

At first, based on the title, I thought this publication was about experiments conducted by a biolab. Then I realized it was another biobank informatics request. The new thing for me was discovering the existence of the GeneCards database (were you aware of it?). It seems to be a different...

Completed. However, I must confess that I likely lowered the averages of this survey significantly because I am excessively fearful.

@Joeseph Stope, thank you very much for your compliments; I am very flattered. As I have already mentioned on this forum, it is thanks to a Google Scholar alert with the keyword “tinnitus” that I set myself the goal of reviewing the publications (around 10 are released almost daily) and...

So, there is a biological difference between mild tinnitus and severe tinnitus: Neural Mechanisms of Tinnitus:An Exploration from the Perspective of Varying Severity Levels And there is a biological difference between acute tinnitus and chronic tinnitus: Decoding Tinnitus Progression...

Tinnitus, lucid dreaming and awakening. An online survey and theoretical implications

https://link.springer.com/article/10.1007/s00405-025-09246-7

Conclusion: Obstructive Sleep Apnea is a risk factor of tinnitus. https://link.springer.com/article/10.1007/s11325-025-03243-0

Here's a new article from Will Sedley and his team: https://link.springer.com/article/10.1007/s10162-024-00970-1

@victoria9273, this is a new related publication, for your information: https://www.mdpi.com/2227-9059/12/12/2837

For those who are interested in this topic: Brainwave entrainment using binaural beats stimulation: Exploring the treatment efficacy in individuals with tinnitus having normal hearing sensitivity

Highlights Noise exposure induced changes in various cerebral regions (cortex, thalamus, hippocampus, amygdala, striatum and cerebellum). Cerebral changes result in disorders (tinnitus, anxiety, depression and cognition impairment). Several antioxidants provide protective roles against noise...

I wasn't sure whether to start a new thread or add to this one, as my experience relates to two specific points: At least twice a week, I actually hear my tinnitus during my dreams. It's "wonderful" (ironically) to realize that even in sleep, tinnitus can still bother me. In these dreams, I...

Although I am French, I am committed to keeping Tinnitus Talk in English for the benefit of everyone. However, I wanted to share information specifically for French speakers: Höra, an app that offers a sound level meter and a speech-in-noise test. This app is supported by the French Foundation...

See my ancient post. To be more precise: I had been taking 8 drops of Clonazepam for over a year, following the advice of my oto-neurologist, without any noticeable effect. So, with my oto-neurologist’s approval, I decided to gradually increase the dosage. At 21 drops, I began to experience...

We all agree that finding a cure is essential. The title of this thread could be improved. I might have titled it something like: “Comprehensive Publications to Explore Brain Systems (including the oto-neurologic system) for Understanding the Pathophysiology of Tinnitus.” This title would...

Finally, some researchers revisited this fundamental question and conducted this experiment. Unfortunately, the results indicate that tinnitus may be even more complex than we previously thought: https://www.researchsquare.com/article/rs-5014033/v1

Sorry for my late reply. Just take a look at my investigation: https://www.tinnitustalk.com/threads/caroverine-and-inner-ear-diseases.1352/

Yet another suspicious hint of the Caroverine mystery: https://journals.lww.com/jfmpc/fulltext/2024/13100/effect_of_oral_caroverine_in_the_treatment_of.80.aspx

Hello everyone, I wanted to make a small contribution by (re)highlighting some exciting information. Unfortunately, there’s no English translation provided by the researchers for the link below, so you may need to use a translation tool: World Premiere: The Brain Revealed Like Never Before...

I'm not sure where to share this publication, but I believe it's worth reading (sorry, only the abstract is available) since it studies over 3 million workers. Perhaps the full article will provide information about tinnitus prevalence, as I received it through a research alert with the keyword...

I'm sorry, but I just came across this publication, so I do not have any further information. Feel free to contact them.

It is a pity the article is behind a paywall. Compared to this thread, similar parameters are acute tinnitus, the hypothesis of neuroinflammation, and rodents. Dissimilar parameters are noise-induced tinnitus instead of salicylate-induced tinnitus and Rolipram (an old drug) instead of TNF. →...

→ The Current State of Tinnitus Diagnosis and Treatment: a Multidisciplinary Expert Perspective

→ Efficacy and safety of SENS-401 in sudden sensorineural hearing loss: The AUDIBLE-S randomized placebo-controlled phase IIb trial

Effectiveness of transcutaneous vagus nerve stimulation for the treatment of tinnitus: an interventional prospective controlled study

FYI: I tried Gabapentin (prescribed by my psychiatrist), 2 pills of 100 mg in the evening for 3 months (July, August and September). No effect on tinnitus, no side effects either.

FYI: I took Tegretol 200 mg in the evenings for 3 months (January, February and March 2022). It was prescribed by my psychiatrist. No effect on my tinnitus. No side effects.

"Ablation of Tbx2 in postnatal, largely differentiated IHCs makes them transdifferentiate directly into OHCs, replacing IHC features with those of mature and not embryonic OHCs." I don't get it. Can someone explain to me? Do we keep this TBX2 in our body (postnatal)? Because nothing happens...

I remain skeptical: gene-editing seems to me like the Pandora Box (cancer triggering...)

This news gives me an amusing thought: the possibility, in turn, of virtually torturing my tinnitus avatar, just to get revenge, as a kind of stress relief. But the worst is that it would be able, given the principle of this virtual reality, to shout in the headphones in return and to hurt my...

Hi, sorry for the delay. Looking at my old blood tests (back to 2013/2014), my maximum dosage was 3,040 mUI/L (according to the tests, limits are 0,270 min and 4,200 max).

I will let you judge by yourself: http://www.hebertlab.ca/en/publications/

Same here after exercise. Coffee has no effect.

Systematic Review on Intra- and Extracochlear Electrical Stimulation for Tinnitus I decided not to create a new thread but to relay this publication under this thread, even if the "electrical stimulation" domain is quite big. My humble opinion is: Paradoxically, it will be easier to evaluate...

I got the answer of my first question: how did they manage to collect inner ear tissue? "To evaluate the expression of SARS-CoV-2 receptors in the human inner ear, fresh inner ear tissue was collected during surgical labyrinthectomies and translabyrinthine resections of vestibular schwannomas...

Prevalence of sleep impairment in patients with tinnitus: a systematic review and single-arm meta-analysis

Another publication from Dirk De Ridder's team: Is the posterior cingulate cortex an on-off switch for tinnitus?: A comparison between hearing loss subjects with and without tinnitus

Genetic predisposition to tinnitus in the UK Biobank population We identified 17 suggestive single nucleotide polymorphisms (p < 1e−5) spanning 13 genes in two sex-separated cohorts reporting chronic, bothersome tinnitus (control males n = 7,315, tinnitus males n = 226, control females...

Genome-wide association study identifies new loci associated with noise-induced tinnitus in Chinese populations Genotyping of 711 noise-exposed male workers of Chinese Ancestry.

@Pete88: to get a biomarker of tinnitus + to predict if a particular treatment will benefit a particular tinnitus patient (before spending money to apply it to the tinnitus patient).

Well I don't get how KCNQ1 can be at the same time a gene and an ion channel. Association Analysis of Candidate Gene Polymorphisms and Tinnitus in Young Musicians

I am little bit surprised this link has not been shared yet since Tinnitus Hub/Tinnitus Talk had heavy involvement in this study. Somatosensory Tinnitus Diagnosis - Diagnostic Value of Existing Criteria

Generalizable Sample-Efficient Siamese Autoencoder for Tinnitus Diagnosis in Listeners With Subjective Tinnitus Electroencephalogram (EEG)-based neurofeedback has been widely studied for tinnitus therapy in recent years. Most existing research relies on experts’ cognitive prediction, and...

Hidden or subclinical cochleopathy in idiopathic subjective tinnitus: extended high frequency audiometry and otoacoustic emission This affection (tinnitus) manifested as elevated EHF audiometry thresholds at 9000, 10,000, 11,200, 14,000 and 16,000 Hz. Most tinnitus patients had pitch matching...

Efficacy of tinnitus retraining therapy in the treatment of tinnitus: A meta-analysis and systematic review

Efficacy of Repetitive Transcranial Magnetic Stimulation (rTMS) for Tinnitus: A Retrospective Study An umpteenth retrospective study about rTMS with a more or less positive conclusion. But this time, some relevant information has been provided: "Repetitive transcranial magnetic stimulation...

I found this publication today using the UK Biobank about tinnitus: Understanding Factors That Cause Tinnitus: A Mendelian Randomization Study in the UK Biobank

For those who are interested/concerned, attached is an article titled: "Inner Ear Disorders in SCUBA Divers: A Review"

Maybe further information about Tzounopoulos research / drug description: The Neuroscience and the Treatment of Tinnitus "We place a special emphasis on mechanism-driven drug development informed by basic research findings.1 Several compounds are under clinical or preclinical investigation for...

Cause of tinnitus is not mentioned though. The Effects of Diet and Physical Activity Induced Weight Loss on the Severity of Tinnitus and Quality of Life: A Randomized Controlled Trial

Hearing loss statistics and forecasts: Hearing loss prevalence and years lived with disability, 1990-2019