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Is there a reason we aren't looking into mGluR group II agonists like Eglumetad or Pomaglumetad? It has already been tested and successfully eliminates tinnitus in mice for a few hours. I spoke to Dr. Galazyuk and they're trying to find funding for this study on humans. @Hazel, has this been...

It would be great if you could test Pomaglumetad on humans for tinnitus. In mice, its predecessor, Egumated, works by reducing tinnitus via residual inhibition in the IC (and also the thalamus). → Residual inhibition: From the putative mechanisms to potential tinnitus treatment

I have tried both of these and wanted to share my experience. I started slowly with 300 mg of Gabapentin in January and increased the dosage to 900 mg by the beginning of March. During this period, I had taken 0.5 mg of Clonazepam a few times, perhaps three or four times, which significantly...

@Hazel, I kindly request some research or experimental treatment on reactive tinnitus. After some polypharmacy, a few months after my acoustic trauma, I got reactive tinnitus, which was quite bad off the start. It was reactive to as little as brushing my teeth off the bat, and within a week, it...

@Theezy, I am glad you are doing better. Tinnitus aside, how have your hyperacusis and noxacusis been during this time?

My life was severely impacted by pure tone neuromodulation. I experienced a tinnitus spike from a medication and came across a video that claimed to calm tinnitus. It initially worked, and I used it at medium volume (approximately 60-70 decibels) on my phone speaker about 8-9 inches away from...

I wonder the same thing. I have extremely reactive variable tinnitus that is driving me to the brink. I had an acoustic trauma in December, which marginally raised my tinnitus. It gave me minor dysacusis and moderate loudness hyperacusis. This was world-changing, but I could still shower, drive...

I am also having a hard time coping with this. I developed loudness hyperacusis and dysacusis in December after following some mild advice to listen to a tinnitus 'relief' video too loudly when my tinnitus spiked due to Visual Snow Syndrome. It didn’t work for me initially, so I turned up the...

I've been struggling with extremely unstable, reactive, and volatile tinnitus for a few weeks now. I'm looking for advice and am interested in knowing if anyone has experienced anything similar. For some background, I had stable single-tonal tinnitus for years until I experienced acoustic...

My question is why did this suddenly transfer to my other ear? What I mean is that the acoustic trauma was 100% localized to my right ear and had distortions ONLY in that ear for a few days. The loudness amplification was also only in that ear. I am struggling to make sense of why my left is...

Do you recommend to slowly introduce myself to sounds now or just wait a few weeks? Also, is the gym safe with earplugs in? Currently anything very high pitch or above room level talking is uncomfortable.

My journey began last weekend when I fell asleep with a headphone in my right ear. I had turned off my music & subconsciously set my alarm to max volume as I do every night, forgetting I still had a headphone in. In my dream I recall hearing a terrifyingly loud high pitched noise, only to be...

Hey. I also recently have been experiencing this. I had an acoustic trauma injury to my right ear last week, and I've been plugging that ear since. The left seemed to be doing fine up until yesterday where it was arguably worse than the right. I went down an anxiety spiral and that is what led...