Can I Take Tizanidine or Does It Make My Tinnitus Worse? Quick Help!
- Thread starter katriina
- Start date
MemberI found that. Was thought your thinking?
How Does Tizanidine Effect Tinnitus?
Tizanidine hydrochloride is a newly developed muscle relaxant which has proved effective in the treatment of tinnitus, but whose effects on the cochlear nervous system remain poorly understood. The present study attempts to clarify this question through an investigation of tizanidine's effects on the auditory brainstem response (ABR) in guinea pigs.
A prolongation of the interpeak latencies between waves I-III was observed following the injection of tizanidine. Statistically significant differences between the tizanidine group and a control group were especially evident 3 to 15 minutes following injection. Decreases in the amplitude of wave III were also seen, with statistically significant differences between the tizanidine group and control group being particularly evident 10 to 15 minutes after injection.
The experiment indicates that tizanidine acts principally upon the central areas of the cochlear nervous system. Comparison of these results with those of other researchers' studies on lidocaine shows that tizanidine's effects on the ABR bear a basic resemblance to those of lidocaine. Hence this agent, like lidocaine, may act to suppress tinnitus principally at the synapses of the central cochlear nervous system.
How Does Tizanidine Effect Tinnitus?
Tizanidine hydrochloride is a newly developed muscle relaxant which has proved effective in the treatment of tinnitus, but whose effects on the cochlear nervous system remain poorly understood. The present study attempts to clarify this question through an investigation of tizanidine's effects on the auditory brainstem response (ABR) in guinea pigs.
A prolongation of the interpeak latencies between waves I-III was observed following the injection of tizanidine. Statistically significant differences between the tizanidine group and a control group were especially evident 3 to 15 minutes following injection. Decreases in the amplitude of wave III were also seen, with statistically significant differences between the tizanidine group and control group being particularly evident 10 to 15 minutes after injection.
The experiment indicates that tizanidine acts principally upon the central areas of the cochlear nervous system. Comparison of these results with those of other researchers' studies on lidocaine shows that tizanidine's effects on the ABR bear a basic resemblance to those of lidocaine. Hence this agent, like lidocaine, may act to suppress tinnitus principally at the synapses of the central cochlear nervous system.
I just got prescribed Tizanidine today to see if it helps me relax and sleep (which has been difficult with tinnitus and headaches that are most likely TMJ related).
I will update with my results!
I will update with my results!
I just now came across Tinnitus Talk, and oh boy do I have a lot to see and say, lol.
But for now, I found myself googling furiously "Zanaflex and ear ringing" because it's just AWFUL. I already have EXTREMELY sensitive hearing - the kind of hearing people think is a blessing but in reality is a loud, overstimulating, exhausting hell.
I mean now I hear everything but it's muffled, accompanied by the brain numbing shrill squeal. Let my back hurt, for real. I can't do THIS.
But for now, I found myself googling furiously "Zanaflex and ear ringing" because it's just AWFUL. I already have EXTREMELY sensitive hearing - the kind of hearing people think is a blessing but in reality is a loud, overstimulating, exhausting hell.
I mean now I hear everything but it's muffled, accompanied by the brain numbing shrill squeal. Let my back hurt, for real. I can't do THIS.
I wouldn't take that list for much. It's sourced from a guy who has a PhD in Forestry and is not a medical expert. I'm really not sure why that list is so relied upon or why it is supported by the ATA.
- May 7, 2015
- 1,050
- Tinnitus Since
- 29.09/2014
- Cause of Tinnitus
- Acoustic trauma using headphones
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