Luxterna was a *huge* deal for congenital blindness and my neighbor's doctors didn't mention it (her daughter has Leber's Congenital Amaurosis) until after the drug came out. She is a nurse (in an unrelated specialty) and actually had to bring the info to them.
FX-322 is certainly not going to cure hearing loss in the next 5-10 years, for many reasons. There's synapse damage, nerve damage, for one. Moreover, what about worn hair cells that haven't died and undergone apoptosis yet? The drug is activated for damaged cells too, but what if there's not enough damage to trigger PCA?
Agree, but it will probably help to know that when LeBel was asked about the damaged but not destroyed hair cell question on the Tinnitus Talk Podcast, he didn't seem to think that was a significant factor.
It's up, it works for me. I also tried one of those "is it down" websites and it said frequencytx.com was up too.
I could prove Bobby's last post wrong in like two seconds but I'm sworn to secrecy!
Ya I think as a professional they should be aware of treatments and research, if not for anything else, to provide hope to their patients. I hate the ones who say "there will never be a cure", it is just as easy to say "I don't know" or "there is research aimed at curing it, we will have to wait and see".
Honestly, that's my motivation for following all of this. I'm in for a long haul. If the company is successful with FX-322, that makes them more likely to be successful with nerve regeneration. Otonomy gives me some hope for synapses. Hough Ear Institute is a little iffy, but with real promising science. Sound Pharmaceuticals' SPI-1005 seems really promising and with the added incentive of helping a global pandemic. Rinri Therapeutics seems like the real deal, but with a difficult project at hand.
If my timezones are correct, they will have just wrapped up their presentation. The wait continues.
Let's say that they do have some success in a few years, ear doctors and the system in Northern California, as being one of 11 megaregions in the US, won't be able to service. The University of San Francisco might. Nationally, New York University and Mass Eye and Ear, but how are they going to handle patient load.
Special trained - this may be the best that we will get, other than from large medical universities.
Exactly, right now it's not an "if" situation. It's a "when"; we're on the waiting game now, with a huge payoff at the end of the line. Let's stay strong for as long as it takes.
Pretty much every employer in the world will refer to new tasks and responsibilities as "opportunities" for the employee. They don't want to say "you will have to use a more advanced machine & headset and administer a more time-consuming test," so it would make sense if this is what they're talking about here.
"Welcome to more work for the same salary..."
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