Again, do what I said. Put on earmuffs for 10-15 minutes and you'll notice how much louder your tinnitus becomes. Then take them off and you'll notice how much quieter it is with the other sound that's now allowed back in. Because it's directly correlated with hearing.
When I read "magical thinking" articles all I can think of is this. (the first prediction is sadly topical)... The second, actually came to pass.This was indeed too optimistic it turns out
I guess before hearing regeneration drugs come out, Prof. Thanos will have his RL-81 on the market.This was indeed too optimistic it turns out
And they could have predicted COVID-19? The plandemic has derailed everything by at least 18 months.This was indeed too optimistic it turns out
That was a delay for sure. The closest thing is probably FX-322 and that's still a good few years away, if it even works. Then OTO-413 is another 4 or 5 years-ish away still too. Everything else is 10 years or more off still.
There are lots of things that can help people significantly. Lots of people find huge benefit in some supplements, exercises, medicine or lots of other things.That dose of reality killed my Monday morning
Yeah, I was just trying to make you feel better. I get sad thinking about how far away a cure might be too but I feel better when I try to distract myself. And probably spending less time on this forum would be better for all our mental health.
This. Also, a great majority of the pharmaceuticals listed are in the pre-clinical stage, which means they're extremely far away.
And the vast majority of them will fail. Most won't probably even make it to clinical trials. Just need one to get through though.
It cheers me up no end to get a view on what research is doing and how it's progressing.
TBH, there's a large part of me that would hate this. I don't want to know how many hair cells I have left in that direct way. If there's no way of doing anything about it, it would just make me crazy.
I'd have to know though. I couldn't help myself, like a junkie. I'd even pay thousands just to see the damage to the stereocilia to further increase my suffering.
That's what I want most. We aren't curing shit if we can't see what is going on. This is especially important, because if there is no hair cell damage, then you know ear treatments won't work for you. And it will also help us better understand the problem and ultimately solve it. I wonder how far we are from that kind of technology, and why. We have the tech to image hair cells in the lab, just not in vivo. I believe that kind of imaging exam breakthrough is by far the most important progress we need right now, and it should have priority over any drug trial. But humans are obsessed with drug trials. It is as if we were trying to fix a virus in your computer by throwing random stuff inside it and hoping something works out. We are so clueless...
Especially nowadays where the Bio-Pharma firms are "tailoring" the patients that are admitted to the trials so as to up the success rate:
Congratulations to him! I know I've watched his December, 2017 presentation at the PSHS more than once! He loves the idea of Neurotrophin-3 (member of the Neurotrophin family of growth factors, same family as BDNF in OTO-413) using it to restore synapses to hearing cells.
This sounds like it could be big! I hope drugs like FX-322 will be able to benefit from this improved delivery method.
@CRGC, as someone in the UK, I can confirm Nottingham University and BRC is the epicentre of tinnitus and hearing loss research. Basically a research centre bolted on to one of the best universities in the country. No biotech/stock market bollocks (stock markets are not a big part of UK society outside of London) or non-profit (disguised for profit) entities like Hough Ear Institute.
That's all great and good but you still get told the same thing.
I agree. I'm not an expert, but I think that many cases of tinnitus and hyperacusis could benefit from treatments to regenerate hearing, however. My problems, for example, coincide with the onset of my hearing loss. If the normal functioning of my cochlear hair cells and auditory nerve could be restored, I believe there would be good chances for me to be cured or at least to experience some relief.
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