MuteButton
- Thread starter Jim
- Start date
- Status
Member- Apr 23, 2015
- 418
- Tinnitus Since
- 01/21/2014
- Cause of Tinnitus
- High frequency hearing loss in left ear from head trauma (?)
- Apr 21, 2016
- 75
- Tinnitus Since
- 12/2014 (mild), 03/15 (severe)
- Cause of Tinnitus
- Head trauma, then acoustic trauma, then more acoustic trauma
Kind of hesitant to bump up this thread - like many here I am extremely skeptical about Mutebutton - but it seems the company is setting up a trial in Dublin: http://tinnitustrials.ie/
Not sure whether to sign up for it or not. On one hand I'm curious in a trainwreck sort of way. On the other hand I'm not sure I can be arsed.
Not sure whether to sign up for it or not. On one hand I'm curious in a trainwreck sort of way. On the other hand I'm not sure I can be arsed.
- Apr 21, 2016
- 75
- Tinnitus Since
- 12/2014 (mild), 03/15 (severe)
- Cause of Tinnitus
- Head trauma, then acoustic trauma, then more acoustic trauma
theekarwash
Member
- Jun 22, 2014
- 158
- Tinnitus Since
- 05/2014
- Cause of Tinnitus
- Noise and/or Ear Infeciton
- Apr 21, 2016
- 75
- Tinnitus Since
- 12/2014 (mild), 03/15 (severe)
- Cause of Tinnitus
- Head trauma, then acoustic trauma, then more acoustic trauma
I applied for the clinical trial and have just received a PFO e-mail stating that I failed to meet their (undisclosed) criteria. Hmmm. Maybe they don't want people with actual post-habituation tinnitus messing up their figures? 
bill 112
Member
It's commencing as we speak Debs,although it's an extremely hard trial to get into,almost everyone I know myself included who applied for the trial have been refused for reasons that weren't made clear.
theekarwash
Member
- Jun 22, 2014
- 158
- Tinnitus Since
- 05/2014
- Cause of Tinnitus
- Noise and/or Ear Infeciton
I applied for the clinical trial and have just received a PFO e-mail stating that I failed to meet their (undisclosed) criteria. Hmmm. Maybe they don't want people with actual post-habituation tinnitus messing up their figures?
I've applied two weeks ago and still haven't received an email back.. I wonder what that means?
- Apr 21, 2016
- 75
- Tinnitus Since
- 12/2014 (mild), 03/15 (severe)
- Cause of Tinnitus
- Head trauma, then acoustic trauma, then more acoustic trauma
They promise a response in two weeks. I got one after a month. As far as I know, no-one from this forum who applied has been accepted. Not that that means you won't be, although it's impossible to say given that they haven't disclosed their criteria.
bill 112
Member
They're very strict for some reason and very obscure with their responses from personal experience with them.I have the phone number for St.James hospital in Dublin if you'd like to try and call for more information.
There are two studies listed on clinicaltrials.gov with the keyword MuteButton. You might be able to get some sense of the inclusion criteria from these studies though inclusion criteria could also be different for this trial.
https://clinicaltrials.gov/ct2/resu...try3=&locn=&gndr=&rcv_s=&rcv_e=&lup_s=&lup_e=
What I find interesting is that the studies were in 2012-2013 but they were not included in clinicaltrials.gov until 2015.
https://clinicaltrials.gov/ct2/resu...try3=&locn=&gndr=&rcv_s=&rcv_e=&lup_s=&lup_e=
What I find interesting is that the studies were in 2012-2013 but they were not included in clinicaltrials.gov until 2015.
theekarwash
Member
- Jun 22, 2014
- 158
- Tinnitus Since
- 05/2014
- Cause of Tinnitus
- Noise and/or Ear Infeciton
From your experience with people you know, are they just not receiving emails back or are they being emailed that they are not being accepted? I'm curious.. The email I received said they'll reply within two weeks if I got through and they haven't in 2 1/2 weeks now..
theekarwash
Member
- Jun 22, 2014
- 158
- Tinnitus Since
- 05/2014
- Cause of Tinnitus
- Noise and/or Ear Infeciton
bill 112
Member
From the people I've spoken to and including myself for that matter we all received an email back saying no without even asking us questions to see if we meet inclusion/exclusion criteria.
Ecip
Member
- Nov 8, 2015
- 686
- Tinnitus Since
- 4.11.2015
- Cause of Tinnitus
- Still unknown... possibly noise exposure?
I think this is the report (abstract) of the study, released today : http://onlinelibrary.wiley.com/doi/10.1111/ner.12452/full
as the Neuromod Devices company (owner of the Mute Button device) is mentioned.
Abstract
Objectives
Tinnitus is the perception of sound in the absence of an external auditory stimulus. It is widely believed that tinnitus, in patients with associated hearing loss, is a neurological phenomenon primarily affecting the central auditory structures. However, there is growing evidence for the involvement of the somatosensory system in this form of tinnitus. For this reason it has been suggested that the condition may be amenable to bi-modal stimulation of the auditory and somatosensory systems. We conducted a pilot study to investigate the feasibility and safety of a device that delivers simultaneous auditory and somatosensory stimulation to treat the symptoms of chronic tinnitus.
Methods
A cohort of 54 patients used the stimulation device for 10 weeks. Auditory stimulation was delivered via headphones and somatosensory stimulation was delivered via electrical stimulation of the tongue. Patient usage, logged by the device, was used to classify patients as compliant or noncompliant. Safety was assessed by reported adverse events and changes in tinnitus outcome measures. Response to treatment was assessed using tinnitus outcome measures: Minimum Masking Level (MML), Tinnitus Loudness Matching (TLM), and Tinnitus Handicap Inventory (THI).
Results
The device was well tolerated by patients and no adverse events or serious difficulties using the device were reported. Overall, 68% of patients met the defined compliance threshold. Compliant patients (N = 30) demonstrated statistically significant improvements in mean outcome measures after 10 weeks of treatment: THI (−11.7 pts, p < 0.001), TLM (−7.5dB, p < 0.001), and MML (−9.7dB, p < 0.001). The noncompliant group (N = 14) demonstrated no statistical improvements.
Conclusion
This study demonstrates the feasibility and safety of a new bi-modal stimulation device and supports the potential efficacy of this new treatment for tinnitus.
as the Neuromod Devices company (owner of the Mute Button device) is mentioned.
Abstract
Objectives
Tinnitus is the perception of sound in the absence of an external auditory stimulus. It is widely believed that tinnitus, in patients with associated hearing loss, is a neurological phenomenon primarily affecting the central auditory structures. However, there is growing evidence for the involvement of the somatosensory system in this form of tinnitus. For this reason it has been suggested that the condition may be amenable to bi-modal stimulation of the auditory and somatosensory systems. We conducted a pilot study to investigate the feasibility and safety of a device that delivers simultaneous auditory and somatosensory stimulation to treat the symptoms of chronic tinnitus.
Methods
A cohort of 54 patients used the stimulation device for 10 weeks. Auditory stimulation was delivered via headphones and somatosensory stimulation was delivered via electrical stimulation of the tongue. Patient usage, logged by the device, was used to classify patients as compliant or noncompliant. Safety was assessed by reported adverse events and changes in tinnitus outcome measures. Response to treatment was assessed using tinnitus outcome measures: Minimum Masking Level (MML), Tinnitus Loudness Matching (TLM), and Tinnitus Handicap Inventory (THI).
Results
The device was well tolerated by patients and no adverse events or serious difficulties using the device were reported. Overall, 68% of patients met the defined compliance threshold. Compliant patients (N = 30) demonstrated statistically significant improvements in mean outcome measures after 10 weeks of treatment: THI (−11.7 pts, p < 0.001), TLM (−7.5dB, p < 0.001), and MML (−9.7dB, p < 0.001). The noncompliant group (N = 14) demonstrated no statistical improvements.
Conclusion
This study demonstrates the feasibility and safety of a new bi-modal stimulation device and supports the potential efficacy of this new treatment for tinnitus.
Pleasure_Paulie
Member
Yes it's mutebutton:
http://onlinelibrary.wiley.com/doi/10.1111/ner.12452/full
https://clinicaltrials.gov/ct2/show/NCT02426671?term=mutebutton&rank=2
Multimodal Stimulation
A combined auditory-somatosensory stimulator was employed in this study (mutebutton@™ model MB2011, Neuromod Devices Ltd., Dublin, Ireland).
http://onlinelibrary.wiley.com/doi/10.1111/ner.12452/full
https://clinicaltrials.gov/ct2/show/NCT02426671?term=mutebutton&rank=2
Multimodal Stimulation
A combined auditory-somatosensory stimulator was employed in this study (mutebutton@™ model MB2011, Neuromod Devices Ltd., Dublin, Ireland).
Pleasure_Paulie
Member
I was called for the initial interview to see if I was suited for the clinical trial of said mutebutton ,they informed me a week later that I was not suited no reason allthough mine was noise induced left ear hissing 24/7 ,I spoke to someone much older than me I'm 44 healthy otherwise she is in her sixties and bought the unit for €2,500 and said it made no difference so I wouldn't be expecting too much ,but wishing I could get some silence.....
- Sep 3, 2016
- 597
- Tinnitus Since
- 2011
- Cause of Tinnitus
- Punishment for being so darn good looking!
Treatment is advancing! I believe we'll be able to drastically cure Tinnitus before 2025, I've read so much research and things like this and it just feels like we are so close to defeating T!!!
- Status