My Posting Place
- Thread starter threefirefour
- Start date
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BrownieBoy
Member
- Aug 7, 2018
- 40
- Tinnitus Since
- June 2018
- Cause of Tinnitus
- Loud concert followed by another loud concert, Dollywood D:
(CAUTION: NOT A SHITPOST)
I keep coming back because you all are the only people who know the struggle. My anxiety is getting the best of me but it helps knowing I'm not alone. I'm almost three months into this life-long battle and will take whatever help I can get. Went to a psychotherapist and he got pissy at me. He said "may your ears ring for that" when I told him I work in marketing. So I said he could call me Haywood Jablome (kidding)
People seem to love kicking a guy when he's down.
@Contrast, why don't you become a gosh darn scientist and bring us all a cure. Big man upstairs knows we need it. Or is this just a test to see how much suffering we can handle?
I keep coming back because you all are the only people who know the struggle. My anxiety is getting the best of me but it helps knowing I'm not alone. I'm almost three months into this life-long battle and will take whatever help I can get. Went to a psychotherapist and he got pissy at me. He said "may your ears ring for that" when I told him I work in marketing. So I said he could call me Haywood Jablome (kidding)
People seem to love kicking a guy when he's down.
@Contrast, why don't you become a gosh darn scientist and bring us all a cure. Big man upstairs knows we need it. Or is this just a test to see how much suffering we can handle?
we know the cure. it's ly411575. you can buy this shit online here:(CAUTION: NOT A SHITPOST)
I keep coming back because you all are the only people who know the struggle. My anxiety is getting the best of me but it helps knowing I'm not alone. I'm almost three months into this life-long battle and will take whatever help I can get. Went to a psychotherapist and he got pissy at me. He said "may your ears ring for that" when I told him I work in marketing. So I said he could call me Haywood Jablome (kidding)
People seem to love kicking a guy when he's down.
@Contrast, why don't you become a gosh darn scientist and bring us all a cure. Big man upstairs knows we need it. Or is this just a test to see how much suffering we can handle?
http://www.apexbt.com/ly-411575.html
fx322 has some other stuff in it too but this is the thing that causes cochlear hair cells to regrow. I'm not brave enough to inject my eardrum with it and I don't know the dose, or how to properly mix it with the gel. I asked my doctor if he would do it and he reassured me that it would be illegal for him to do so.
No, I'm not qualified I am a college drop out after hearing damage ruining my life.(CAUTION: NOT A SHITPOST)
I keep coming back because you all are the only people who know the struggle. My anxiety is getting the best of me but it helps knowing I'm not alone. I'm almost three months into this life-long battle and will take whatever help I can get. Went to a psychotherapist and he got pissy at me. He said "may your ears ring for that" when I told him I work in marketing. So I said he could call me Haywood Jablome (kidding)
People seem to love kicking a guy when he's down.
@Contrast, why don't you become a gosh darn scientist and bring us all a cure. Big man upstairs knows we need it. Or is this just a test to see how much suffering we can handle?
the only thing I'm doing is trying to find logic behind tinnitus by looking for patterns, similarities and observing cause and effect scenarios, 95% of what I mention about tinnitus has something to do with what researchers have already suggested.
tbh I have no idea no one else does the same.
I refuse to believe that tinnitus is some super complex boogie man mystery, everything has explainable logic behind it
BrownieBoy
Member
- Aug 7, 2018
- 40
- Tinnitus Since
- June 2018
- Cause of Tinnitus
- Loud concert followed by another loud concert, Dollywood D:
I know we all have our own stuff to deal with but you're committed to the cause and I look forward to seeing your posts. Thanks for trying to keep us all in the loop and hopeful for a cure. Seriously, thank you! Putting all of my chips on 2023 being the breakthrough year where we can see some relief.
Maybe @Bill Bauer is right and we will spontaneously heal if we take the proper precautions. It helps to have hope
It could very well be much sooner. If fx322 actually works I think it will be 2020-2021. Its already well into phase 2 and theres only 3 phases.
a few months ago some guy on this forum confronted me acting like I was just making stuff up at tinnitus and hyperacusis. Something along the lines of "what are you from the 2030's where the hell are you getting this information, are you a time traveller from the future, we even know if it's bent hair cells or in the brain"?
After that I sent links them links from Frequency Therapeutics website explaning the hair cell regeneration process, a few articles about the central gain hypothesis where I amatuerlishly tried to explain parts of it. and studies on hidden hearing loss, ear plug, ear wax, stadectomy, and cochlear implant statistics.
I even apologized for speculated about Frequency Therapeutics and early on doing alot of speculating.
and he blocked me as if I was a quack who was totally full of BS.
I'm just seeing if this forum could have a tinnitustalk.com/sciencebehindtinnitus
section that explains the known mechanisms of tinnitus and hyperacusis and causes
It would have to be reviewed by actual researches, it's just ashame knowing how many people join this forum with hidden hearing loss and act like nothing'swrong.
After that I sent links them links from Frequency Therapeutics website explaning the hair cell regeneration process, a few articles about the central gain hypothesis where I amatuerlishly tried to explain parts of it. and studies on hidden hearing loss, ear plug, ear wax, stadectomy, and cochlear implant statistics.
I even apologized for speculated about Frequency Therapeutics and early on doing alot of speculating.
and he blocked me as if I was a quack who was totally full of BS.
I'm just seeing if this forum could have a tinnitustalk.com/sciencebehindtinnitus
section that explains the known mechanisms of tinnitus and hyperacusis and causes
It would have to be reviewed by actual researches, it's just ashame knowing how many people join this forum with hidden hearing loss and act like nothing'swrong.
This forum gives people the right to be dead wrong about what caused their tinnitus.
They could believe in homeopathy, reflexology, Chinese medicine or some superstitious/highly questionable alternative nonsense that caused their tinnitus and no one will bother correcting them if people like myself don't jump on it.
Thankfully the majority of people on this forum aren't like this. From what I see years ago it was a lot worse with homeopaths.
The main problem isn't quackery, it's simply ENT's not keeping up to date with research about hidden hearing loss and TRT/CBT being put before a treatment.
They could believe in homeopathy, reflexology, Chinese medicine or some superstitious/highly questionable alternative nonsense that caused their tinnitus and no one will bother correcting them if people like myself don't jump on it.
Thankfully the majority of people on this forum aren't like this. From what I see years ago it was a lot worse with homeopaths.
The main problem isn't quackery, it's simply ENT's not keeping up to date with research about hidden hearing loss and TRT/CBT being put before a treatment.
@BrownieBoy, one thing that might help is adjusting your expectations of healing time from months to years. Sounds harsh but know that each year gets a little better. Think of it as "calluses, scabs or scar tissue" forming verrry slowly. A finger nail takes 6 months to grow back, another 6 months to thicken and still longer before it feels normal, like the original.
Nerves take even longer! I damaged a nerve in my finger once. It went numb and stayed numb for a long time! Like two years before the nerves grew back and feeling regained. I had a habit off rubbing my finger with my thumb testing it.
My ears were blasted June 2013. I told myself not to expect any change the first three years, the forth a little better and after five years a notable difference.
For the first years I was aware of different frequency tones. After three or four years they almost seem to blend together. The sharp edges get dull, the distinct screeching begins to lose its chalkboard effect.
I know it sounds like a long time (and your case may not take as long as mine) but at least there is hope if you're patient. Don't fight it. Adjust your life to fit T. Don't expect T to adjust to your old self.
Hope this helps. I know how difficult it is. You will adapt, you must. Everyone is here for you.
PetitGarsTimide
Member
- Jan 6, 2018
- 225
- Tinnitus Since
- 2016
- Cause of Tinnitus
- Dumb teenager who listened to loud music everytime
PetitGarsTimide
Member
- Jan 6, 2018
- 225
- Tinnitus Since
- 2016
- Cause of Tinnitus
- Dumb teenager who listened to loud music everytime
Of course I am ASSUMING that fx322 is the cure for tinnitus. So having direct knowledge of this I do not. So I could have worded that differently. It is more of an educated hypothesis.
Ly411575 regrows triggers PCA regeneration of cochlear hair cells in vivo:
http://www.illustratedcuriosity.com/health/health-medicine/ly411575-a-drug-that-restores-hearing/
I'm not 100% sure that this chemical, ly411575, alone is what they used, but it kinda seems that way.
Patent info for fx322:
https://patents.google.com/patent/US9968615B2/en
"Differentiation of Lgr5-Positive Progenitor Cells Stem cell colonies are differentiated in a 1:1 mixture of DMEM and F12, supplemented with Glutamax (GIBCO), N2, B27 (Invitrogen), with addition of specific drugs or after removal of growth factors without drug addition. The specific drugs are added to the culture to test their effect on differentiation.
The specific drugs used in the assay above are agents that help drive differentiation. Non-limiting examples of the specific drugs used in the assay above include gamma secretase inhibitors (e.g., DAPT or LY411575), Wnt activators/GSK3 inhibitors (e.g., Wnt3a, R-spondin, CHIR99021, GSK3 inhibitor XXII, AZD1080, etc), antibodies, peptides, siRNA, or a combination thereof."
MPP research team plan of action:
1. Start independently investigating supplements, foods, techniques, habits that have an affect on symptoms.
2. Seriously, keep a diary of your food, drink, medicine intake, and sleep (hours, quality, etc) and quality of symptoms every single day.
3. Be damn sure you do step 2.
4. Periodically report any changes in symptoms , good or bad to the MPP research team.
That's what we should do, its loose science but it is still qualitative investigative research. If we start feeling like something is working for better or worse then we move to quantitative research.
@JohnAdams and @Contrast begin official research on investigation of regenerating cochlear hair cells in adult mammals. 2018, colorized.
hey I already asked you but I forgot ... what is the name of the treatment that worked for you?
This is from the bottom of my heart:
I have been thinking deeply about habituation. I'm actually habituated 80-90% of the day because I use masking sounds, and other spiritual, not psychological, techniques to just not let it affect my emotions as much as possible. And I fully realize that habituation doesn't mean that the T is gone. I never read a book about habituation. I never paid any therapists. It is something that CAN just naturally happen as you adapt as a human being. I don't understand why anyone is getting paid to research this stuff. Habituation is great and totally necessary but I don't believe for one second any human being on the face of the earth should make any money helping people to habituate, ESPECIALLY IF they don't have tinnitus. Honestly I believe that if you don't have tinnitus, or you've never been locked in a dungeon and tortured by inquisitors then you have no business trying to help any of us. That's like trying to be a consultant on climbing Mt. Everest and you've never climbed even a tiny mountain. This isn't engineering or math, this is raw suffering, and no PhD holder can possibly understand the reality of having your life turned completely upside down from a pervasive neurological disorder unless they have experienced it themselves.
I have been thinking deeply about habituation. I'm actually habituated 80-90% of the day because I use masking sounds, and other spiritual, not psychological, techniques to just not let it affect my emotions as much as possible. And I fully realize that habituation doesn't mean that the T is gone. I never read a book about habituation. I never paid any therapists. It is something that CAN just naturally happen as you adapt as a human being. I don't understand why anyone is getting paid to research this stuff. Habituation is great and totally necessary but I don't believe for one second any human being on the face of the earth should make any money helping people to habituate, ESPECIALLY IF they don't have tinnitus. Honestly I believe that if you don't have tinnitus, or you've never been locked in a dungeon and tortured by inquisitors then you have no business trying to help any of us. That's like trying to be a consultant on climbing Mt. Everest and you've never climbed even a tiny mountain. This isn't engineering or math, this is raw suffering, and no PhD holder can possibly understand the reality of having your life turned completely upside down from a pervasive neurological disorder unless they have experienced it themselves.
@threefirefour you dumb normie, the mp3 comes from a url that ends an a .mp3 extension not a Youtube video.
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