Please be strong and have hope. If anything, help us research naturally occurring notch inhibitors. Is it a stupid notion? That some flower or tree extract taken in high doses could not do the same thing as a lab chemical? This is all new science. I believe this thing is achievable.
1. Tinnitus is probably caused by hearing loss, which is largely caused by sudden loss of the little hairs in our inner ear.
1. Tinnitus is probably caused by hearing loss, which is largely caused by sudden loss of the little hairs in our inner ear.
2. These little hairs can, but dont naturally grow back because of chemicals in our body preventing them.
3. They found out VERY recently that these hairs can be induced to regrow and restore hearing with a class of drug called a notch inhibitor.
4. That's what fx322 is. In phase 2 trials now.
5. Within the last few years, these notch inhibitors have been found in many plants.
6. We are perhaps 4 months away from knowing the effects on tinnitus of fx322, if they report this after phase 2 is over in December.
7. I'm either stupid or smart because I think theres a chance I can replicate hearing regeneration with some yet unknown to me plant.
8. Have a nice day.
I think that if fx 322 test subjects report that they had T and it went away, that they will approve it for that. If not, this technology will be replicated in other countries like Mexico and Taiwan etc and you'll be able to get it there where there are less regulations. Better be, I dont think my hearing loss is detectable either.
A consumable substance that promotes the regrowth of cilia. Sounds simple enough and seems plausible. But there is no such consumable substance to regrow hair on a bald scalp. So how can this be possible in my cochlea and only my cochlea?
1. Tinnitus is probably caused by hearing loss, which is largely caused by sudden loss of the little hairs in our inner ear.
2. These little hairs can, but dont naturally grow back because of chemicals in our body preventing them.
3. They found out VERY recently that these hairs can be induced to regrow and restore hearing with a class of drug called a notch inhibitor.
4. That's what fx322 is. In phase 2 trials now.
5. Within the last few years, these notch inhibitors have been found in many plants.
6. We are perhaps 4 months away from knowing the effects on tinnitus of fx322, if they report this after phase 2 is over in December.
7. I'm either stupid or smart because I think theres a chance I can replicate hearing regeneration with some yet unknown to me plant.
8. Have a nice day.
I do know that cochlea hair and head hair are in fact two completely different things.
Yes. To clarify further for anyone who is wondering, cochlear "hair cells" are not hair at all. The cells are only named such because they resemble hair in appearance.
I found out it took 3 months for the mice treated with ly411575 to recover to their maximum potential.
LMFAO!!!! THERE'S ALREADY A THREAD ON THIS.
https://www.tinnitustalk.com/threads/regeneration-of-the-cochlea-notch-inhibition-lllt-—-a-theoretical-approach.8418/
That settles it for me, I'm going to become one with the curry.
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Veggie capsules of the pure stuff. I'd say a reputable natural foods market. I got the one in the link I posted earlier from a store called Earthfare, a super snooty rich hippy grocery store here in USofA. It absorbs poorly and needs some kind of black pepper or something to go with it. I'm going to find out a maximum safe dose and start taking it everyday. It may take up to 3 months to see any results. You could try it with me. We shouldnt get our hopes up too high lest we be let down too hard, but hey, it's worth a try. Really anything at this point is worth a try. I'm also going to go to the doctor every couple of weeks to get my blood work done to see if I'm hurting my kidneys while I do this.
The different cells react to notch up regulation and down regulation differently. There are 4 different notches.
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