• This Saturday, November 16, you have the chance to ask Tinnitus Quest anything.

    The entire Executive Board, including Dr. Dirk de Ridder and Dr. Hamid Djalilian are taking part.

    The event takes place 7 AM Pacific, 9 AM Central, 10 AM Eastern, 3 PM UK (GMT).

    ➡️ Read More & Register!

My Posting Place

LiveLeak-dot-com-1414919459_goat_twisting_neck_1539727508.gif
 
Just before I got T I saw the story of a Dutch guy in Bristol whose insane ex acid attacked him when he was sleeping. She fucked him up real bad. It burnt through the entire bed and carpet. I thought at the time that has got to be the worst thing EVER. This comes a close second. And considering he's now euthanised himself I'm actually undecided. At least he didn't have years of 'am I ever gonna get better or should I just off myself tomorrow' torment.
I would be lying if I said I felt differently.
 
frequency tx is a joke and theyre just circle jerkin the fda. wake up people. we just need an ent that will inject our ears with egf, 7,8 dhf, and bisphosphonate. I hate this world.
 
Here is a list of heroes:
-Beethoven
-Mandy Harvey
-Grimes

Who did I miss?

Edit - also Mandy Harvey's "Sensing the Rhythm" is an amazing book - for any of you fellow musicians with hearing loss.
Although, I don't believe she has T.
 
I just don't fucking get it. My uncle is/was a musician (drummer) his whole life, he is damn nearly deaf and has absolutely no tinnitus. Here I am who generally took good care of his ears and went to one concert too close to the front and now can barely stand it. I almost feel like it people who have it with hearing loss don't mention it because they think it is a weakness.
 
I just don't fucking get it. My uncle is/was a musician (drummer) his whole life, he is damn nearly deaf and has absolutely no tinnitus. Here I am who generally took good care of his ears and went to one concert too close to the front and now can barely stand it. I almost feel like it people who have it with hearing loss don't mention it because they think it is a weakness.
Damn, me too, just one night completely did me in. And yeah it's so mysterious to us. I have a relative with severe hearing loss and no T either. It's so crazy.
 
Just came across a thread talking about "pycnogenol", what do you guys think?

I did find positive info here https://www.ncbi.nlm.nih.gov/m/pubmed/24988090/ BUT it's talking about Meniere's patients, not people with NIHL (like me), also no mention of control group receiving placebo (Ugh).
@JohnAdams
 
Apparently there will never be a Dank Fortnite Dance thread. Lame! Mods told me I have to get along with the old people on here regardless of your ability to yeet. Also got myself banned to just using general chat. Double Lame! I'll repost my introduction story here since it was removed because it was too dank and i was dropping truth bombs on the other posters.

My name is fourfrostfive. Named myself after I saw someone named @threefirefour on here and thought how he looked like a default skin wearer in fortnite, So to one up him I named myself fourfrostfive. My other nick names and online personas are Yeetmaster & Dank Dancer. I am a professional dancer, but i mainly do the fortnite dances. I won my schools talent show by doing all the dances in fortnite without making any mistakes. I know you guys would prob break a hip if you even tried. #dabonthehaters

The story of how I got tinnitus is as follows. I was at my friend cody's house for some dank fortnite teams. We were dropping FAT YEETs left and right while blasting some lilpump and lilxan. I know you old people prob don't know who they are, but rest assured they are better than jimi hendrix and the rolling stones combined. anyway it is tradition that when we get kills we all jump up in real life and do our favorite fornite dance. My favorite is obviously the floss so I can floss on the haters all day left and right. Anyway we dropped a stinky yeet on the last team and won the game. Obviously in the hype of the moment I jump on my bros couch and start doing the fastest most intense floss dance the world had prob ever seen. Unfortunately, my friend kyle had spilled some mountain dew code red on the couch and during my floss of the century i started to fall forward toward codys glass table. My friends tried to grab me and pulled my arms back, but they were too late. Fortunately for me before my face smashed into the glass table shattering it, my boy andrew pushed the bowl of cheetos in front of me protecting my face from being scratched by the glass. The best part was that they were flaming hot cheetos which are my favorite. Ever since then I have had somatic tinnitus because of the pain in my neck from the injury.

I do plan on continuing to pursue my dream as a professional dancer regardless of T because of the god sent TRT that I am receiving. I see a lot of you haters hating on TRT & Jastreboof, but imma just dab on you all to block out the noise. I know you won't believe me, like my science teacher doesn't believe the earth is flat, it is what it is.

anyway, my mom took away my xbox because I was busting some FAt Yeets at school and got in trouble so here I am.
 
Donald Trump buys MPP.
I just don't fucking get it. My uncle is/was a musician (drummer) his whole life, he is damn nearly deaf and has absolutely no tinnitus. Here I am who generally took good care of his ears and went to one concert too close to the front and now can barely stand it. I almost feel like it people who have it with hearing loss don't mention it because they think it is a weakness.
Damn, me too, just one night completely did me in. And yeah it's so mysterious to us. I have a relative with severe hearing loss and no T either. It's so crazy.
an unknown triggers (possibly low GABA, stress and or TMD, + hearing loss = tinnitus.
maybe pain/hyperacusis is similar, we don't know that for sure.

tinnitus in all likelyhood is like a phantom sensation an amputee experiences. Tinnitus may be the phantom limb equal of feeling control of the lost limb/hearing and hyperacusis may be the pain of the lost limb.

not all amputee's have phantom limb pain, some have it and it fades. not all hearing loss sufferers have tinnitus and some have it and it fades.

but remember no one knows anything about tinnitus, BUY TRT!
 
So I have been thinking lately about the effects of drug administration directly to the cochlea. Provided that we do have a working drug there are several methods:
1. Micro needle - there remains the problem of cleaning/closing the puncture wound after administration of drug and hitting the target of the round window on the cochlea
2. Drug pump - considering that too much of a drug can be given at once leading to further hearing damage, the flow will be regulated through a push/pull gravitational system. This is one of the most effective methods, however, it is also invasive as it is an implant so surgery has to be performed
3. Magnetic administration - this is what Otonomy is working on. This will allow the drug to penetrate the membrane using the power of magnets (no puncture or incision necessary)
4. Oral - this is the most preferred option but it's downside is in order to get enough of the drug in the bloodstream to reach the cochlea, it has to be taken in high quantities which can cause problematic side effects and/or be potentially fatal
5. Intravenous delivery - again, could be very dangerous like the oral method

If there was an easier way for inter-cochlea delivery, we would have a hell of a lot better time controlling the doses of a drug so that it can get to where it needs to be. Otherwise, there is no way even a working candidate can be properly tested.

More reading can be found here:
https://www.tandfonline.com/doi/full/10.1080/17425247.2018.1444026
 
amptutee's experience phantom control of the limb, and phantom pain.
these are two separate experiences

Just like tinnitus and hyperacusis
upload_2018-10-16_23-7-21.png

filling in the gap for the audiotory nerve's missing input (tinnitus)
and damage to the AN itself (hyperacusis pain)

How do we prove/disprove this hypothesis?
 
tinnitus research should be testing these kind of hypothesis.

Would cochlear hair cell/synapse regenerate help tinnitus?
once again the biggest claim about CI's having a 100% success rate on tinnitus is on Med-El's website and they are a cochlear implant retailer and I could not find their study. An actual study showed CI's to have a high success rate with few exceptions. We can't explain the exception and a good scientist wouldn't ignore it.
 
tinnitus research should be testing these kind of hypothesis.

Would cochlear hair cell/synapse regenerate help tinnitus?
once again the biggest claim about CI's having a 100% success rate on tinnitus is on Med-El's website and they are a cochlear implant retailer and I could not find their study. An actual study showed CI's to have a high success rate with few exceptions. We can't explain the exception and a good scientist wouldn't ignore it.
Perhaps, but a cochlear implant is not treating the tinnitus, it is treating the hearing loss. So hypothetically, if you increase the input (hair cells/nerve fibers), then that will decrease the tinnitus.

Step #1: Determine methods/drugs that will promote healing/create new hair cells & fibers (which we are still on) then
Step #2: Do studies that correlate the two together
 
Perhaps, but a cochlear implant is not treating the tinnitus, it is treating the hearing loss. So hypothetically, if you increase the input (hair cells/nerve fibers), then that will decrease the tinnitus.

Step #1: Determine methods/drugs that will promote healing/create new hair cells & fibers (which we are still on) then
Step #2: Do studies that correlate the two together
I can't do studies

tinnitus research all goes to habituation studies.
 

Log in or register to get the full forum benefits!

Register

Register on Tinnitus Talk for free!

Register Now