My Posting Place
- Thread starter threefirefour
- Start date
MemberI'm not a huge frequency fan but that's not the horse I'm betting on. Yeah I totally think that they will be the ones to regenerate hearing, but maybe not in the 20's.I really do want Frequency to succeed but I just have so little hope... How do you all even stay optimistic?I just feel like it's a pipe dream...
It's okay to have little hope. Considering there has never been a breakthrough treatment in history for tinnitus it's pretty justified.
As it stands frequency therapeutics CAN regrow hair cells and can transfer it into human tissues. The problems are things like the hairs are too long, it's hard to get it passed the lower frequencies, and the hair cell growth isn't controlled. They also haven't regenerated much hearing in a test so they need to work on that. There's hurtles sure but I feel the huge ones have so far been overcome. Now for the tricky little things, but little things can stop a project.
Frizz
Member
- Feb 16, 2018
- 78
- Tinnitus Since
- January, 2018
- Cause of Tinnitus
- Elephant ear washer (Ear syringing)
Is there a horse you're betting on? Shore's device? Her device sounds like residual inhibition almost but more physically based...
I think everyone who keeps up with tinnitus research has a "horse" they think will win, or be the first or best treatment. Personally I don't think curing HL will fix tinnitus because I have tinnitus but no HL. It will probably make it quieter though and I still support frequency therapeutics. If I had to choose to ensure the success of either FTX or Susan Shore, I would pick FTX because it would help more people. Susan Shore is still the horse I'm betting on.
And what her device aims to do is shutdown fusiform cell activity in the DCN that causes tinnitus. Even if it was RI it still lasts for a decent amount of time.
They failed to regenerate much hearing in a mouse with profound deafness.
They openly admitted their drug does not work on profound deafness due to lack of progenitor cells
Much more hair cells would have been regenerated on mild to moderate hearing loss one would assume.
In nature when birds and reptiles regenerate hair cells they have the same problem of the high frequency hair cells sterocillia being longer like low freq hair cell stereocillia. That problem is still a ???, but better then not having hair cells
A legitimate concern is growing too many hair cells in the lower frequencies.
PetitGarsTimide
Member
- Jan 6, 2018
- 225
- Tinnitus Since
- 2016
- Cause of Tinnitus
- Dumb teenager who listened to loud music everytime
Frizz
Member
- Feb 16, 2018
- 78
- Tinnitus Since
- January, 2018
- Cause of Tinnitus
- Elephant ear washer (Ear syringing)
Sorry I'm going to get negative here and vent. If this type of thinking is unwelcome here I promise I won't do it again. I'm just so frustrated.
I just have next to no hope for this... Science is just not cyberpunk enough yet for something so ambitious. Even advancements in other more promising health fields like protein therapy in Alzheimer's is going to take ages before they perfect it and put it on the market, despite recent success. No one really cares about hearing loss and Frequency seems like such a tiny company, and even if they do by some miracle cure hearing loss I don't know if it'll do anything at all for my hyperacusis. My hyperacusis is now less the recruitment-based "All sounds are loud" but the more insidious nerve-related "A day after five seconds of what would be harmless loud noise my ears are on fire for a week." which no one knows how to manage other than living in ear plugs forever because one burst of noise can cause a setback after a month of progress.
What a life. Though it really isn't one at all.
I really wish I could be hopeful, but I guess some advancements are better than nothing at all. I have faith cures will come, but maybe in like 50-100 years, at best. Shore's device, nerve painkillers, and other forms of "relief" seem more realistic in the short run.
PetitGarsTimide
Member
- Jan 6, 2018
- 225
- Tinnitus Since
- 2016
- Cause of Tinnitus
- Dumb teenager who listened to loud music everytime
Frizz
Member
- Feb 16, 2018
- 78
- Tinnitus Since
- January, 2018
- Cause of Tinnitus
- Elephant ear washer (Ear syringing)
Having autism and borderline makes me a defective human being, neuro-healthy minded people are evolutionary hard wired into being rude and making sure I am socially excluded.
@threefirefour how does it feel being weeded out from the gene pool?
Our lives are basically examples of unfavorable traits being weeded out from the gene pool.
@threefirefour how does it feel being weeded out from the gene pool?
Our lives are basically examples of unfavorable traits being weeded out from the gene pool.
About normal. Wasn't planning on bringing little atusistlets into the world anyways.
i really want to fucking die, my life is a suicide recipe.
new bad news comes in and now i know i'm going to be awake for the next 36 hours panicking
Log in or register to get the full forum benefits!
Similar threads
