Sup, Tinnitus Talk~ Freshie Here

[egowisp]

so i'm new, but also not new? i've been lurking since last year sometime; mostly checking in on the support sections, but i randomly felt like making an account. to follow a few users that seemed pretty knowledgeable + threads that interested me but w/e

so i do have a few questions! 1, is there a general vent or chat thread i could use? secondly, what project in the tinnitus world do you have your eye on?

i faintly recall a pill that could restore hearing loss? i think it was in the early stages of testing, or something...that interests me.

anyway anyway i may not be that terribly active here, but i do hope we get along ^_^. also hope we all get a cure, proper treatment, or just general good news within the next few years!

 

[Contrast]

pill that could restore hearing loss?

Are you referring to the work of Frequency Therapeutics, Decibel Therapeutics and Otonomy. They are working on medicines directly injected into the inner ear to regenerate hair cells and reconnect nervous tissue with hair cells. It's not a oral pill more like an injection inside the inner or particle transfer inside the inner ear.

I have my eye and ear on Decibel Therapeutics and Otonomy because they are focusing on the most common form of hearing loss that is called cochlear synatopathy (death of cochlear ribbon synapses) which causes trouble hearing in background noise.
http://investors.otonomy.com/news-r...ents-data-highlighting-potential-oto-413-otic

 

[egowisp]

Are you referring to the work of Frequency Therapeutics, Decibel Therapeutics and Otonomy. They are working on medicines directly injected into the inner ear to regenerate hair cells and reconnect nervous tissue with hair cells. It's not a oral pill more like an injection inside the inner or particle transfer inside the inner ear.

i feel like this may be it? the pill was cx-[something], far as i can remember. but i could be remembering wrong haha
what you linked looks interesting, though the idea of getting an injection in my ear is unsettling
but i'd def do it, if it could rid me of t

 

[JohnAdams]

i feel like this may be it? the pill was cx-[something], far as i can remember. but i could be remembering wrong haha
what you linked looks interesting, though the idea of getting an injection in my ear is unsettling
but i'd def do it, if it could rid me of t

fx-322?

 

[Zeneth]

There was something about epilepsy pills helping people with tinnitus? And Dr. Thanos Tzounopoulos was given a 2 million dollar grant to research into that I think.

 

[Bill Bauer]

secondly, what project in the tinnitus world do you have your eye on?

Hearing Regeneration Trials

Spoiler

Frequency Therapeutics - FX-322
in Phase 1.5 (Results: December 2018)
Phase 2 (begin 2019)
Audion / Regain Trial
Phase 1/2 ongoing in the UK
Genvec / Novartis - CGF166
Phase 1/2 ongoing

Trials to begin in 2019 / Things to look out for in 2019

Spoiler

Neuromod (MuteButton)
launching their new device in January 2019 starting in Ireland, then Europe, then the US
results of their latest trial: 1H2019
Xenon Pharma - XEN-1101
Phase 2, expected to wrap up in 2nd quarter 2020
Frequency Therapeutics
Phase 2
Otonomy
1H19: OTO-313 (reduce tinnitus) Phase 1/2
1H19: OTO-413 (repairing synaptic damage) Phase 1/2
OTO-6XX (hair cell regeneration)
2H18: candidate selection
2019: Phase 1/2
University of Minnesota (device for tinnitus)
Phase 3 ?
University of Michigan (device for tinnitus)
perhaps updates on their currently ongoing trial
Estimated Primary Completion Date: September 2022
Estimated Study Completion Date: January 2023

 

[Bill Bauer]

so i do have a few questions! 1, is there a general vent or chat thread i could use?

Search the Support forum to find any threads related to your question. If there is such a thread but your question hasn't been fully answered there, post your question there. Otherwise, create a new thread for your question.

 

[egowisp]

fx-322?

yeah !! this is it
i recall you posting about it lol
thanks

 

[Contrast]

Have you heard of MPP, it's a cool thread where we post memes and promote research.

https://www.tinnitustalk.com/threads/my-posting-place.23694/page-320

 

[Phendran]

Hello lurker-no-more.
We hope you will find a place here with us until the day we are cured.