I don't know for sure, but into the second week of taking 8 grams per day I started having long stretches of no tinnitus. I dont think you can stay on that much indefinitely. I stopped yesterday. Tinnitus is right back.@JohnAdams, so is curcumin good for tinnitus due to noise induced (hearing loss) ?
I've been taking it twice daily for close to 6 months now. I believe it's helped overall, but I'm also on many other supplements and doing daily exercises, so it's hard to say if my gains are directly linked or not.
Here's the product I use:
https://www.amazon.com/gp/product/B01MCUYRBO/ref=oh_aui_detailpage_o00_s00?ie=UTF8&psc=1
Not right now. I'm currently taking egcg and I'm about to start taking it with thunder god extract. I'm not trying to just lower my t but heal myself.Thank you for the response! @JohnAdams have you thought about trying it out again?
I wanted to share my experience.
I had to take prednisolone for a skin issue a few months ago.
I noticed while taking it that my head hissing tinnitus was greatly reduced.
Once I stopped, it came back.
I thought maybe there was an inflammatory link to my main tinnitus - (Please note that I do have a mild ringing in my right ear due to a notech at 6000 kHz and this noise hasn't stopped since taking the curcumin).
I tried curcumin a little while afterward, and sure enough, reduced head hissing.
Not sure why now, but I discontinued use and head hissing came back to normal.
Just back on curcumin and head hissing greatly reduced.
I will continue for the foreseeable future and keep everyone updated.
Like a day or 2.@Samantha R @JohnAdams
How long after taking curcumin did you notice a change in your T? I recently started taking it and am wondering if what I am feeling is placebo or actual side effects of curcumin.
Like a day or 2.
@Zeneth
No, I don't, I am getting results with much less.
My dosage at the moment is 800mg per day (split in to morning and night).
I suspect inflammation is the cause of my tinnitus, and I'm more sure now.
Results with prednisolone and now with Curcumin.
I do get hormonal fluctuations as well so will be interesting to see how things go throughout the month.
The background (quickly to my onset) - tinnitus 1 month after C-section delivery of twins, gestational diabetic. I was unwell shortly after the birth and felt "not right"for at least 2-3 weeks post birth.
OB told me at my 6 week check that there were some inflammatory markers in my blood when they ran some tests after I complained of feeling unwell.
I have a mild ring in my right ear that I believe is related to a 30db loss at 6,000khz. This remains unchanged on curcumin (and I can actually hear it now, it is normally dominated by the hiss). I am habituated fully to that noise.
The hiss however is much milder at the moment (I can't hear it unless in a relatively quiet environment and focusing on it).
It seems that curcumin is otoprotective if taken before trauma.
View attachment 23247
https://www.sciencedirect.com/science/article/pii/S1347861317301093
But after trauma if you take it, spontaneus regeneration (which is miserable itself) wont occur due to lack of Atoh1 expression.
"We have shown that the response of cells in the utricle to an ototoxic trauma involve changes of Notch signaling molecules and Atoh1 expression. Using qRTPCR we detected down-regulation of Hes5, up-regulation of Atoh1 and no changes in levels of Notch1, Jagged1 and Hes1
Atoh1 was not detected in the normal tissue but appeared after the trauma. qRTPCR data showed a post trauma decrease for Hes5 and an increase in Atoh1 after the lesion, with no significant change in Notch1, Jagged1 and Hes1."
View attachment 23248
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902641/
Curcumin is just a factor whose presence stops expression of Atoh1. After washing it out, situation is reversed.
"To test the contribution of ongoing acetylation to hair cell differentiation, HATi was removed from some cultures at the 24 h time point. These washout experiments demonstrated that changes brought about by HATi were reversible, and differentiation resumed upon drug removal."
View attachment 23246
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2902641/
I'm going to start take curcumin along with NAC to prevent damage from any unexpected sudden noise.So what does this mean? Curcumin if taken before noise induced trauma can reduce the damage similar to NAC? Same thing for ototoxic drugs?
I'm going to start take curcumin along with NAC to prevent damage from any unexpected sudden noise.
Yes. It can reduce.Being a stupid person I am offended you didn't include a TSTU (too stupid to understand) somewhat similar to a TLDR.
So what does this mean? Curcumin if taken before noise induced trauma can reduce the damage similar to NAC? Same thing for ototoxic drugs?
@JohnAdams weigh in?
Yes. It can reduce.
Curcuma longa (curcumin) decreases in vivo cisplatin-induced ototoxicity (...)
https://www.ncbi.nlm.nih.gov/m/pubmed/24608370/
There are so many many plants that protect from noise and drugs. It's very common. If you want I can write a list of some otoprotective herbs.
Harder is to find a thing that helps when damage is already done. This is the key.
Yes, please provide a list that would be fantastic. Are there more studies that I can read into regarding reducing the damage of ototoxic drugs with supplementation?
Are drugs that cause tinnitus to temporarily spike considered ototoxic? Things like caffine or alcohol? I wonder if taking curcumin can reduce the spike caused by that in people who have problems with it.
I know @coffee_girl says he tinnitus spikes after coffee. I wonder if her supplementing curcumin could reduce it.
I don't know anything about curcumin but nac pills work wonders on me...it eliminated the screeching completely... And it's safe to take everyday, perhaps try those too. I'm afraid to take pills so I try not to risk it. Coffee has worked to ease my anxiety and had never given me any problems besides a minor spike. But the benefits it gives me far exceed the consequences. Just my opinion.Yes, please provide a list that would be fantastic. Are there more studies that I can read into regarding reducing the damage of ototoxic drugs with supplementation?
Are drugs that cause tinnitus to temporarily spike considered ototoxic? Things like caffine or alcohol? I wonder if taking curcumin can reduce the spike caused by that in people who have problems with it.
I know @coffee_girl says he tinnitus spikes after coffee. I wonder if her supplementing curcumin could reduce it.