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I agree with this, unfortunately. I'm not immediately suicidal but every month that passes, I lose more lifelines so I can't guarantee this won't be me at some point. But I also know it won't change anything. Early on a friend told me, "listen if anyone in the world can hack this, it's you."...

http://www.acousia.com/pipeline/otoregeneration/ In general, I'm not too excited about methods which involve reprogramming support cells to turn them into hair cells because it depletes support cells, which have a function in maintaining hair cell health. So, not only would your new hair cells...

You will probably never acknowledge this because you admire Trump too much but he often takes credit for things he has nothing to do with. He was already touting record stock numbers early in his presidency when he hadn't enacted any policy that would have affected them. He was coasting off of...

No but it's missing the point.

And weirdly rats seem among the most empathetic. A rat will preferentially pull a lever (when trained and given the choice) to help another rat in distress over food, access to mates or drug rewards. Mammals are wired for love and nurturing. Look at Koko the gorilla and her pet cat.

One of the two main reasons for Trump's popularity: The other is to play into people's conspiracies and make them afraid of not supporting you.

Funnily enough, my first idea was having aot pull up in a Convertible, turn down Will Smith's "Miami" (before you could hear it) then taking you both to Cassadaga to mess with the "Psychics" there. I chose this instead because: 1) My writing is shot now and this could be written quickly...

I have sort of a joke idea for this in the writing style of a very "distinct voiced" poster but I can't actually do this. Lol.

Okay done. It was written in about 20 minutes so I hope your expectations are low.

Even though I owe @aot some public embarrassment, there were many directions I could go with this and I went with wholesome :) ------------------- “Steph and Andre” by FG “Right there. Starbucks.” Steph reached her arm from the back seat to point out her destination for the Uber driver. She...

Okay, fine. I did write something short really quick. I used to write a lot so I give this a 2/10, want me to post it?

I really want to listen to a Lydia Loveless album right now and it's making me so sad that I can't :(.

Don't tempt me, I may do this.

This is really cute. I should write fan fic about you two meeting :).

It's funny that this research was being published in 2020 as there was a researcher nominated for the Nobel Prize in medicine named Fuad Lechin decades ago who discovered that neurotransmitters could modulate the immune system (before him and people like him, the assumption was it was an...

To be fair to @thinlay, the sarcasm in @Tezcatlipoca's post is probably only obvious if you have been following other threads.

It used to be a fear of mine (and maybe still is) that there is a God and his values don't match with what I see as loving and "good." And, of course, maybe I am wrong in my subjectivity but some of the "rules" seem so arbitrary to me (not mixing fabrics in clothing comes to mind) whereas...

I have thought of something similar in the Arkansas Ozarks, remote and relatively cheap. It's something I have considered if I have to sell my house but you are a lot more likely to be able to do this than me (I'm guessing). I would join you in a second. Any peace is so hard to come by...

So, the idea is we can't be the judge of "good" because we are too subjective but God is "objective" so we need him to judge. I have heard this argument before and I see where it comes from because "good" is in the eye of the beholder in more complicated situations, especially. But in...

I did a Twitter search and found a lot of recent write ups but nothing about what they are doing in Taiwan and India. Do you have a link?

I have a friend who had breast cancer treatment and they subtyped her *extensively* by what genes she had and what receptors her tumor was positive for and planned treatment accordingly. Her treatment was a success because they knew what drugs would work for her and it was not the "standard"...

Well a month out is pretty far out for oral steroids to do much. I thought it had worsened sooner than that. I would take the first available appointment and try to get them to do an emergency referral to an Otologist if they can't help you. They still might be able to do intratympanic steroids...

Past the acute stage, viral mediated hearing loss is usually permanent but the tinnitus from it can fade over time. I would think inflammation from the vaccine would have a better prognosis since it should be more transient. 2.5 weeks out is about the limit of where steroids might help so it...

Sudden hearing loss is a medical emergency, in many cases the sooner you treat it the better. The first 72 hours especially. Do not let them blow you off. Tell your ENT you have sudden hearing loss and have them work you in on emergency. If they can refer you on emergency ASAP to an Otologist...

Yeah it's weird to think it's just completely arbitrary and the companies want to limit their applicant pool for absolutely no reason.

This one: https://www.soin-et-nature.com/en/dry-cough-medicine-online-pharmacy/16331-ambroxol-eg-labo-30mg-30-tablets-dry-cough.html

If you have substantial hearing loss (or did that resolve?), they need to treat this aggressively. What was the dose of steroids they gave you? I would try to be seen ASAP by an Otologist (have your ENT give you an emergency referral) especially if you have sustained hearing loss (but I would go...

Devices have a very, very low bar compared to drugs. I think Lenire is crap but I bet it gets approved.

Blood flow good, pressure bad is probably the best way to explain it. The alpha blocking properties of Vasobral possibly could help but the central serotonin and dopamine effects can worsen tinnitus so I personally wouldn't take it. The absolute best thing you can take for your middle ear...

I take Fish Oil, and already stretch. I can do breathing exercises as long as breath holding isn't involved as I'm trying to increase middle ear oxygenation. Weirdly, it's only when I wake up. Last it went away on its own. I just think I'm prone to this everytime I get a new "hell" to deal with.

A month maybe? It definitely doesn't make my head feel pressurized. It actually fully alleviates the "fullness" feeling in my ears as well as significantly helps with face pain.

No. Viral vectored therapies have to be directly inserted into the cochlea. That's a big problem with them. Akouous has come up with a new surgery though involving Stapes venting which is less destructive.

I'm not sure how to read this. It does look like the 40 µg dose was most effective if I'm reading this correctly: Particularly for lower frequencies, which would make sense since their surgery was really inflammatory/destructive for higher frequencies especially it seems. Also possible they...

Hmm. Maybe I will look into SGB myself. My fight or flight in the last few months has been insane. I literally wake up from a dead sleep with a racing heart every single morning now. I had that early on and it lasted 8 or 9 months but with the new noxacusis symptoms, it's back in full force and...

I saw a psychiatrist early on, too (at my ex husband's insistence, not another doctor's--they didn't push that since I had abnormal otology results). I was pleasantly surprised when she told me that I had some PTSD symptoms but (and she directly said this) it sounded like one of my biggest...

I would get a consult with a rheumatologist and see what they think. If the antibodies are significant, they may want to start you on an immunosuppressive and they could also do further testing to rule it in/out as a co-factor.

The dose I started with was 30 mg three times daily. I'm not sure if it will help you or not without trigeminal pain but if it does, you would probably notice at least some difference in a day or two as it works fairly quickly. I think you need to "drink the whole thing" but if 30 mg every 8...

You can definitely recover to the point of living a full and normal life, however it seems that many people with mild hyperacusis who have a noise trauma later develop more serious hyperacusis. It's good that you have not had any setbacks but I would personally from this point on err on the...

That's sort of the problem. Everything is so individual and depends on the cause and individual pathology. That's what makes all this stuff so hard to navigate. If you do end up trying LDN and it makes it worse, I would definitely stop and not "push through." It's interesting that you had such...

Ambroxol is not much of an "anti inflammatory". You probably are feeling the effects on your ET resulting in less pressure build up if you feel those effects. The humidity from a warm shower may be helping open up your ETs as well. It is good for facial pain as well through sodium/calcium...

I think my love language is quality time, touch and researching the crap out of things for people.

"Thoughts and prayers" are so popular because it's literally the least you can do sometimes.

It seems good for helping to clear out the Eustachian tube and is great for facial noxacusis pain, too (works on the same sodium and calcium channels as Lidocaine). It doesn't penetrate the BBB or presumably the blood cochlear layer well but if you had some middle ear stuff contributing to your...

I'm sorry for my contribution to the de-railing of the photo thread. Lol.

Seems like it would have pros and cons. I think self esteem issues with people who have had their lives uprooted are at least as big of a factor, though.

Nah. This one would work probably. And you can't argue with success.

You are totally stealing my line...

It looks the move was planned since at least last December too: Frequency Therapeutics plans HQ move for early next year

Ideal response from a normal person: "In that case, why don't you come over since we can't sleep anyway?" Response from someone on this forum: "What frequency is yours? Mine is like a 12000 Hz pure tone and I can hear it on both sides and..."

If you could find a doctor to do this, you could have it done now. Whether or not the study is successful this isn't really an outpatient procedure, so you would have to find a clinic or hospital willing to do this (or move near one) if it helped. With the inclusion of the fMRI, it seems less...

So they are trialing this for intermittent relief. That's good news.

Would be nice if he followed up. I wonder if this has been tried the way IV Ketamine has. Even though it can cause heart problems if given inappropriately it can treat others. At least a few people must have gotten it therapeutically IV who had tinnitus so it would be nice if there were data...

Oh IV. Yeah that makes more sense :). If anyone even thinks of trying this at home you will need to dilute it and do it insanely slow. Can cause fatal arrhythmias. FYI.