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ROCK 'N' FUCKIN' ROLL, E!!! I'm overjoyed for you. Nice timing too with Spring just around the corner. Much love to you and Mrs E.

Thanks, Ann! :beeranimation: EDIT: It got pinged back: I found reference to his personal website with contact details on LinkedIn but that timed out. Dunno...

I recently happened upon this paper authored by, Thomas Gisiger and Mounir Boukadoum, entitled: Mechanisms gating the flow of information in the cortex: what they might look like and what their uses may be Although there is no mention of tinnitus in the paper, the references to neural AND...

@Elmer B Fuddled, how you doing, E?

To be honest, I've largely skirted the "type of damage" debate because of the major problem I see with quantifying it. But I do think this is where Peter McNaughton's work can be interesting with, "temporary tinnitus after hearing damage", being a good example. We could have a case of...

This recent study on mice discusses links between neuropathic pain and hyperacusis. There's evidently quite a bit of research into the role myelination plays in neuropathic pain so it looks like the common denominators are there whether it's visual or auditory systems.

Thank you @Markku, @Hazel and the rest of the team for another fascinating podcast. It was a great listen. I find Prof. McNaughton's ideas intriguing, and would echo what he said insofar as it's always good when someone new comes along and shakes up the field. Tinnitus as a peripheral...

Nearly there, E. At least the end's in sight.

Try following them on LinkedIn. Or subscribe to the UMich Innovation Partnerships newsletter.

Did anybody press him on that comment? I can't remember... I've just done what I felt I had to and acquaint myself with these processes since Neuromod really started to look like a serious contender six or seven years ago (or however long it was). Regarding the age of this thread, you're quite...

Based on 50% of the pivotal trial data being unusable. We don't need to know about that. 50% of the data is unusable. Whatever they have been working towards cannot now be delivered. Read the first line of my post again. Then consider the facts and weigh these against the balance of...

Obviously speculation, but based upon the available facts and balance of probability, this is the situation as I personally see it: Regarding trial criteria, the UMich team set the bar of clinically significant effect as low as possible. This is detailed in one of the post-trial Q&As Susan...

When tinnitus becomes severe, it can be a very cruel and demanding condition that few people, even those who "have tinnitus," can understand. You're doing the best you can. You have to keep living your life.

I'm not sure I agree with the argument about self-reporting anti-depressant efficacy and the absence of an external reference point. It's scarce for patients to exist in a bubble; those around a patient taking anti-depressants will notice improvements in their mental state when the medication is...

He made that comment about 5 years ago here. I like that Dr. Nagler posted on Tinnitus Talk, but I do take issue with that particular comment. If the volume doesn't closely relate to the level of irritation or intrusion, then we're back on that slippery slope to CBT. I don't discount CBT...

Strange that it costs £110 to access that 2015 paper; I'm able to view the full document clicking your link. I'm not overly familiar with Rauschecker's most recent work, but the tinnitus paper of his that I generally draw on is this one. I've read comments that it's an overly complicated paper...

Within that statement lies the pretext for Jastreboff's infamous comment likening those of us who don't respond to his TRT protocols as "white flag wavers." To the best of my knowledge, Jastreboff's generation of tinnitus thesis has never actually escaped the textbooks and led to a final...

Merry Xmas everyone. Second half of 24's been a bit rough my side. Ears ain't getting better and that's where it's at. But somehow, I keep chiselling on through. If I can do it so can you. Big chin up for '25 to all my tinni pals :beeranimation:

Happy Days!

Big shoutout to @MindOverMatter one of the best dudes on here :beeranimation:

Glad to hear you're doing well, mate.

Re delivery; I believe there are already suitable systems out there. For example, I can't see why a modified TORS machine couldn't be used.

Re delivery; the needle trajectory absolutely does require the scraping or drilling of bone - "trephining" as the study refers to it. This occurs at the modiolous wall of the cochlear "for a median depth of 1.48mm". Access to that part of the anatomy would be gained via the round window with...

The above article answered the below question:

I still strongly believe that the root cause of tinnitus lies in a defective (for the most part, congenital) neural-noise gating mechanism. It's the only conclusion I've ever been able to reach, other than "bad-luck", which is not very scientific, that explains why some people get tinnitus...

Hey, D. I went through a period of reading Philip K. Dick novels. I think he's a superb author who almost invented a genre of his own but I did find myself having to really bump up my mood prior to starting each book because many of his stories would either severely p*ss me off or play too much...

Regarding those who struggle intensely; you're quite right when you say "that level of struggle is not the norm". Nevertheless, the problem with a comment like that is that a significant number of people new to Tinnitus Talk appear here struggling intensely - lack of sleep, hyper-focus, anxiety...

Thanks for the link. What Hamid has provided there makes for interesting reading. I think he's on point with a lot of what he says, but I disagree with him on point 7: Distinct from Hyperacusis: Although sound sensitivity may be present, the primary complaint is an increase in tinnitus...

I've spoken to a few people from the charity sector about the current situation at Tinnitus UK and they all opine the same thing, more or less: the charity has been mismanaged. I don't really know the details of their financial situation but Tinnitus UK lost me when they started with this...

Sound familiar?

I've not seen a diagram referencing the Cochlear device, and on a technical level, the information they've supplied to date lacks the relevant detail, so there's some presumption on my part. My belief is that a sound processor sits over the ear (in the same position as a hearing aid) and that...

We have a saying in England; same shit, different colour.

Hello, mate. Sorry I didn’t reply earlier—I’m still not receiving alerts when tagged. I was also a bit confused when researching these latest updates because I’ve seen references to both “on the promontory” and “in the promontory,” which suggest two very clinically different setups. However, I...

My NHS audiology dept. promised me CBT a couple years ago but never got back in touch (even to this day). I dabbled with the idea of paying privately and ended up having an email exchange with Debbie Featherstone, who provides the CBT4T programme you've linked to above. I was really impressed...

Good luck with it, mate. I'll be thinking about you.

I always thought there was a lot to be said about this type of human connectivity to the ground. We have a particular radiator in the house that is prone to discharging angry sparks when touching it while wearing slippers. When I think ahead and remember to take off the slippers, I'm already...

@Wouter De Blaere, I'd tend to agree with what @Nick47 has said above that the symptoms outlined, delayed as they may be, are likely linked to hyperacusis. Frank Magnusson over at Hyperacusis Research wrote an interesting account of his own experience. In it, he mentions the delay factor, or...

What's your point of view on 26 years of research? 11 years ago on the first post of this thread, Susan Shore stated in an interview that they were excited about this device because, "It's not just something we cooked up. It's based on 15 years of research."

Disclaimer: I haven't read the paper as I'm maxed out reading tinnitus research for now! ----- At the very least, I think where any tinnitus treatment study is concerned , particularly where the researcher is a young scientist, we should consider trying to pair the study team with the Bionics...

This describes my own tinnitus perfectly; the reactionary feedback loop being the thing that causes me the most distress. I attribute this to the addition of hyperacusis, and from what you've written, it sounds like hyperacusis has presented itself in your situation, too. 7 years ago my...

Yeah, it's been a long haul!

They didn't appear to. They used a "hydrotransmissive" method requiring filling the external ear canal with a saline solution then setting an electrical probe (that didn't touch the walls of the canal) into it. Goodness knows how they managed to keep the saline from trickling out. I think it's...

I think this is extra-cochlear stimulation? Probe + saline solution inside the ear canal. Anyhow, regardless of that, the more of these study papers I see, the more bewildered I get. We're literally staring at an open goal. I even wonder about the point of Tinnitus Quest in this regard. The...

It might depend on how they/we define sound processing. I mean, hearing with or without tinnitus is all sound processing to a degree, just "normal" or "abnormal" processing. If they're measuring tinnitus "severity," then going off what I personally experience with reactivity, I'd expect to see...

Thanks for the update; it looks quite encouraging. "Firstly, it provides definitive evidence that the tinnitus diagnostic tool developed by our researchers can detect changes in tinnitus severity" I wonder if this opens up further avenues to measure "reactive tinnitus"? "our upcoming clinical...

Hi Frédéric, I remember the first time you shared this info and being quite intrigued by it. From the article: "Structural abnormalities could be associated with psychiatric disorders such as schizophrenia" Along the way in my own research I've often felt there could be some kind of...

Mine's been sh*te recently as well to be honest. Me and Mrs UKB flew down to Spain today, so I was expecting the worst, but thankfully, the earplugs seemed to have done the trick. Small victories. Speak soon, man.

We're living in clown-world, mate.

Literally the best news! Overjoyed for you, E.

Even if the treatment is going to be a real grind, it sounds like you managed to catch it early, which is great news.

Good luck, E. I'm rooting for you.

This "different types of tinnitus" perspective is what has ultimately led to "muh heterogeneity" and the endless conveyor belt of clinical researchers all needing "another ten years" and a horde of gerbils. The solution to tinnitus starts with one decent executive project manager. If these...

I drop by every couple of days or so to keep up with the research threads, etc, but for the most part, I try and get on with life. You know how it goes, E. Did you ever complete that log cabin, or is the project on hold for now?

Whatever happens and however it goes, E, you'll get through it x

Thank you, Ann! I'm not annoyed. Frustrated perhaps, but not annoyed. My comments are observations (right or wrong) about how ongoing research functions. This is just me trying to piece together what I've recently learned is actually a rather long history of extra-cochlear electrical...

Yes, I understand that. Maybe that's not been made super-clear. Brian Fargo donated $1m for what appeared to me - further research, trials, etc. If we're beyond that phase and now into "getting his device to market," well... I know from my perspective, I'd be pretty excited about that. But...

On the funding question, I've donated to Tinnitus Talk over the years and been happy to do so because I always felt @Markku & @Hazel were out there fighting our corner. Since learning a bit more about the history of direct electrical stimulation of the cochlear, however, a treatment that was...