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Can't decide whether to take Prednisone for a spike or not. It sucks because you never know if its going to get worse or better.

Anyone have any experiences with Ambien?

Hope everyone is doing somewhat better :)

@Padraigh Griffin, yhank you for this detailed post. I am not well versed in the anatomy of the ear, but do you know, if you get these surgeries, will intratympanic injection treatments still work? Like for example intratympanic steroids or if OTO-313 ever came out? I assume this is not reversible?

Did the Prednisone help?

Been dealing with a spike for the last two weeks, I got Prednisone on hand debating if I should take it or not, any input?

How is your ETD now?

Although it is a little over a week, you may still be in the time period for steroids. You also have hearing loss, so that kind of indicates the use of steroids. Ask your ENT or doctor asap what they think and if they can prescribe it. It is one of the few things that can help hearing loss and...

@Matchbox, I hope you are doing better these days. I've kept up with your posts ever since I first joined, you are in my thoughts my friend.

I wanted to bump this thread because I have seen some positive reports of Ambroxol among some hyperacusis users, particularly sufferers with Trigeminal Neuralgia symptoms. Has anyone tried Ambroxol recently? How was it and what dosage?

Hello everyone, I have a flight coming up tomorrow that I must go on, and I have hyperacusis and ETD which complicates things. I am going to take some Sudafed, NAC, and anti-anxiety medication to calm my nerves before the flight. Might even use some Flonase before the flight as well. It is a...

I think this is a great idea. These organizations are supposed to represent us, but we aren't seeing much from them at all. There seems to be a great disconnect between Tinnitus Talk and these organizations. Perhaps if we can connect with them, it will be beneficial for tinnitus sufferers. (I...

Well it is good to hear that at least the hyperacusis got better for you. Do you wear hearing protection in public? How are everyday noises for you, like dishes, A/C, stuff like that?

I don't have any advice on how to taper Ambien, but how is your dizziness and hyperacusis doing now? I think I have similar symptoms caused by Ambien.

How are you doing now?

Does anyone know of anyone who has had this surgery done in California?

I was doing good with regards to my tinnitus and hyperacusis. I recently started taking Ambien and I had a setback. Feel like crap now. Wonder if the Ambien is why.

You probably need to be an American citizen, didn't realize you weren't one. I'm sure you can find something similar in your area. Just look up "Prednisone prescription online".

Speaking of the Prednisone, you can use this website to get it prescribed: https://www.pushhealth.com It is a 100% real website and I have used it in the past. You can get a prescription for like $65. Just make sure when you go to the pharmacy you use GoodRx coupons to get the best price on...

This might be a possibility. There are some people out there who can't go numb from local anesthetic. I spent a lot of time looking into this. Check out this article: The people who can’t go numb at the dentist’s It appears that a similar numbing agent is used for the ear...

My right ear (Good ear) hurts a little bit after a very loud car drove by. Should I be concerned?

Do you still have the ear fluttering? Has anyone else had ear fluttering symptoms disappear after a while?

How are you feeling now @Matchbox? Hope you are doing as good as you can, sending prayers your way.

In the Tinnitus Talk Podcast it was confirmed that the placebo formulation is the exact same as OTO-313 minus the drug, as said in this quote at around 41:42: "To put this into context, the placebo is the same formulation as OTO-313, just minus the drug, so it's not a difference in if a true...

For future reference, for the Frequency Therapeutics webcast website you can register with any name, company name and e-mail address. Just make up a company name and you can go ahead and watch.

Has anyone else on Tinnitus Talk tried Vinpocetine?

By vehicle, do you mean the placebo contains similar compounds as OTO-313 but no drug? If that's the case, it seems kind of dangerous to have sustained release placebo... I don't know.

Does anyone know if the placebo is sustained release as well? Because if that is the case, doesn't it seem kind of dangerous to inject something that won't do anything to the ear and could only worsen it? Maybe that is why the placebo had more adverse effects?

What is the best way to talk to friends while playing video games without using a headset? Looking for a boom mic setup or something

It's always sad for me when the Research News section is slow :(

So when's the next big date on results for FX-322?

Alcohol most definitely helps

Those new Mac Minis with the M1 chip are great value for their price, considering the inflation of PC parts at the moment, and it won't even be that loud. If you are looking to upgrade that could be a good choice for you depending on your needs, I believe it was $100 off at Costco a while ago.

Damn you got a really nice build. I'm jealous lol. I want to get one of the new graphics cards as well but they are just so hard to get at the moment.

Here is mine, I built this a little bit before the GPU price hikes and all of that: CPU: Ryzen 5 3600 GPU: XFX RX580 originally had a Sapphire Pulse 5600 XT but I returned it when I got a PS5 pre order RAM: 32gb DDR4 Storage: 1 TB MX500 SSD + 256gb SSD Motherboard: MSI B450 Tomahawk Max PSU...

This never really crossed my mind. I wonder if it is possible for CRISPR to help tinnitus? There is hype with Neuralink with tinnitus but CRISPR might come sooner than that.

I honestly don't see how a chiropractor can help you with ETD. I think you might be better of trying long term use of steroid nasal spray and making sure it goes to your eustachian tubes. I have seen some people on this forum report success after using the spray for multiple weeks, however I can...

Relief cannot come sooner

I was thinking about this earlier today. If you are under anesthesia, is it still possible to get hearing damage even though you are not conscious? I wonder if there has been any studies on this because it seems like an interesting concept.

Now the question is, will there also need to be additional studies if this were the case? Like in order to get both, would there need to be further safety and efficacy studies to see if it's okay to get both?

I wish OTO-313 could lead to total remission. Well, I'll take whatever I can get. Any improvement is better than nothing. I wonder as more time goes on after receiving OTO-313 if it would lead to further improvement or return to baseline. I'm just glad that there is some success at least.

Okay, so I was thinking about OTO-313 and then I realized that OTO-313 isn't really a cure, it seems like it mostly just improves symptoms for people by reducing their TFI score. As far as I know there hasn't been a total remission of tinnitus for those who have received OTO-313. I believe...

I'd like to throw in another vote for Susan Shore and Hubert Lim. I also think it would be very beneficial if we can get an ENT organization/society on the Tinnitus Talk Podcast. I feel like ENTs are very disconnected from the reality of how tinnitus is for a lot of patients and I think...

Can I ask for a source on this?

So I am not really good with knowing how companies operate and stuff but I think I have a rough idea of what's going on here. I believe they had $86 million in cash on hand, then earlier this month they secured another $30 million in financing, and I think another $15 million on top of that? In...

So I am not entirely sure what it is either, but I did a little bit of googling so I am going to try my best to answer this, hopefully someone else can chime in as well. Here's what I found: "These trials consist of two phases: the usual dose escalation phase that aims to establish the maximum...

Sorry for the late response. I am going to basically paraphrase what Dave Weber said in the video. I think there is a lot of technical stuff throughout the whole video that you can probably understand better than me. If you can manage to watch it yourself there is a lot of juicy stuff after 30...

So I am not really well versed with the implications of your question, but one thing I can say is the video I linked took place on the 13th of April and the share thing happened earlier today. Hopefully someone else can answer your question but based on the video they emphasized that they have a...

I don't think anyone has posted this video yet but this is pretty interesting (you can use any name/company and email to sign up): https://wsw.com/webcast/needham107/otic/2250710 Some things to note: They have enough funding until Mid-2023 apparently Q2 2021: Initiate OTO-413 Expansion Study...

In what way does this help? I've been interested in trying Kava Kava for a while but I am not sure on how to proceed with it because it is confusing on what to get.

Thanks for the pictures. I must also say that is a nice setup. Can I ask how you got Tinnitus Talk in dark mode as well?

I've been spending alot of time on this forum, hoping to find some kind of advancement everyday. We are all in this together

So I have high hopes for OTO-313, as it is one of the few things in the pipeline that is originally indicated for tinnitus and not something speculated for. I hope it will work for people with chronic tinnitus, but since I am in the acute stage with unilateral tinnitus I am thinking about...

I thought it would be similar to that. Thanks for the info. It would suck for anyone who has an HMO to do something like this because they tend to be more conservative.