Choice of Stem Cells

[Vincent R]

@DebInAustralia had good results from some other clinic but wasn't sure if it was really because of the stem cells or just natural healing.

Reading her story, I doubt it was natural healing. I believe the treatment worked somewhat.

Fun fact: The doctor who carried out the treatment is a loose cannon. I researched him: a former beauty surgeon who turned to stem cells for money. He got a client killed due to unprofessionalism.

I'm personally not interested in stem cells harvested from my own fat, but I think it could be an option for those who want to try stem cells without paying too much.

 

[SmallRonnie]

@SmallRonnie, do you know some people from this forum who did the tinnitus treatment by StemCells21? And what where their results?

It's all in the thread here.

I think there are 3 or 4 people at least in that thread who had good results but there's a lot of info there and you need to research it yourself.

 

[SmallRonnie]

Reading her story, I doubt it was natural healing. I believe the treatment worked somewhat.

Fun fact: The doctor who carried out the treatment is a loose cannon. I researched him: a former beauty surgeon who turned to stem cells for money. He got a client killed due to unprofessionalism.

I'm personally not interested in stem cells harvested from my own fat, but I think it could be an option for those who want to try stem cells without paying too much.

Yeah the adipose stem cells are better for things like joint pain.

It's so hard to research these clinics. There are so many horror stories and stories of scam clinics.

 

[Engel]

It's all in the thread here.

I think there are 3 or 4 people at least in that thread who had good results but there's a lot of info there and you need to research it yourself.

These four people had the treatment years ago. Is there nobody who have done it this year? Or someone who will soon do the StemCells21 tinnitus treatment?

 

[SmallRonnie]

These four people had the treatment years ago. Is there nobody who have done it this year? Or someone who will soon do the StemCells21 tinnitus treatment?

You could email StemCells21 and ask them to put you in contact with some of the people they recently treated. That would probably be your best bet. If you do, then report back here to tell us.

I know a few people from Tinnitus Talk are also considering it. I am most likely going to get some stem cell treatment somewhere relatively soon but just not sure where yet. Still contacting several clinics.

Why do you want to know about recent cases though? I really doubt they changed their procedure but who knows. It's always going to be a pretty big risk since it's not certified treatment.

 

[SmallRonnie]

Newish study on stem cells.

They say that dental pulp stem cells are better than bone marrow stem cells. Bone marrow and adipose do seem to be much less potent than umbilical cord too.

This study is showing how stem cells produce BDNF and NGF.

This study shows how NGF improved hearing and tinnitus in people when injected just behind the ear.

Seems like local injections of stem cells, like they do in StemCells21, actually could be really good. Such a shame it's so astronomically expensive.

Also, @Cal18 got injections of stem cells just behind the ear which helped her hyperacusis although she did say the improvement was minimal, that was short term result though and stem cell results are usually better after several months.

BDNF is also the drug they use in OTO-413.

 

[James Connelly]

I asked Innate Healthcare what their method of administration was and I got the below reply. Using the term 'throwing out the idea of developing an ear drop solution' doesn't fill me with hope that it could end well or with some success.

We use a multitude of administration techniques including intravenous (IV), intramuscular (IM), intranasal (IN), intraarticular (IA), or even intraperitoneal (IP). We've been throwing out the idea of developing an ear drop solution with MSCs but haven't had a true need for it with our patient base as of late.

When addressing a TBI specifically, I presume the doctors would recommend an IV and IN administration.

 

[James Connelly]

Newish study on stem cells.

They say that dental pulp stem cells are better than bone marrow stem cells. Bone marrow and adipose do seem to be much less potent than umbilical cord too.

This study is showing how stem cells produce BDNF and NGF.

This study shows how NGF improved hearing and tinnitus in people when injected just behind the ear.

Seems like local injections of stem cells, like they do in StemCells21, actually could be really good. Such a shame it's so astronomically expensive.

Also, @Cal18 got injections of stem cells just behind the ear which helped her hyperacusis although she did say the improvement was minimal, that was short term result though and stem cell results are usually better after several months.

BDNF is also the drug they use in OTO-413.

Are you any closer to picking a clinic? I think I'm going to go for it early next year.

Has anyone actually had success on here with stem cells and hearing loss or have they all been tinnitus sufferers?

 

[SmallRonnie]

Are you any closer to picking a clinic? I think I'm going to go for it early next year.

I'm not sure really. I took a deep dive into ordering a bunch of supplements and peptides so I want to try a quick course of that.

My tolerance to noise is still too low to travel on a long plane journey. I will probably go to some clinic in a few months but it all depends on how much better my ear is getting.

I think some supplements like NAC, curcumin and other anti-inflammatories might increase my tolerance to noise or reduce the chances of another setback anyway.

There was an amazing court case decision on stem cells in the US recently by the way.

 

[James Connelly]

'm not sure really. I took a deep dive into ordering a bunch of supplements and peptides so I want to try a quick course of that.

My tolerance to noise is still too low to travel on a long plane journey. I will probably go to some clinic in a few months but it all depends on how much better my ear is getting.

I think some supplements like NAC, curcumin and other anti-inflammatories might increase my tolerance to noise or reduce the chances of another setback anyway.

@SmallRonnie, that's fair enough. I emailed Innate Healthcare asking them about the quality of their stem cells and they came back with this...

When they say each cell needs 46 chromosomes and they're counted in that number of 300 million, does that mean you're actually only receiving 6.5 million stem cells? Do you know if other companies quote chromosomes in their figures for stem cells e.g., StemCells21's 100 million package?

 

[SmallRonnie]

@SmallRonnie, that's fair enough. I emailed Innate Healthcare asking them about the quality of their stem cells and they came back with this...

When they say each cell needs 46 chromosomes and they're counted in that number of 300 million, does that mean you're actually only receiving 6.5 million stem cells? Do you know if other companies quote chromosomes in their figures for stem cells e.g., StemCells21's 100 million package?

View attachment 51550

I'm not sure about the exact number of stem cells really. It's very hard to know the quality between clinics. That response sounds good but every clinic is always going to have a good response like that. There is that other clinic in Phoenix and they provide much less stem cells for the same price so who knows.

 

[James Connelly]

I'm not sure about the exact number of stem cells really. It's very hard to know the quality between clinics. That response sounds good but every clinic is always going to have a good response like that. There is that other clinic in Phoenix and they provide much less stem cells for the same price so who knows.

I'm going to have a consultation with them. I might as well do it. It's $11,500, considerably less than StemCells21 and if I get some benefit for my TBI issues, then it's only a positive.

 

[KotaDomowa]

Are you any closer to picking a clinic? I think I'm going to go for it early next year.

Has anyone actually had success on here with stem cells and hearing loss or have they all been tinnitus sufferers?

Maybe me next year.

 

[SmallRonnie]

Has anyone actually had success on here with stem cells and hearing loss or have they all been tinnitus sufferers?

There was that trial on 11 children and half of them had improved hearing after stem cells. I read one paper where people's hearing improved when injected near the ear with BDNF and NGF which are secreted by stem cells, so would probably work too.

I don't think the people who went to StemCells21 had any hearing loss. Someone did show an audiogram of before and after stem cells in StemCells21 and the hearing did improve slightly but it's impossible to know if that was real or not.

 

[James Connelly]

Maybe me next year.

Have you decided which clinic? It's such a big decision and the number of stem cells on offer and price vary so much.

 

[KotaDomowa]

Have you decided which clinic? It's such a big decision and the number of stem cells on offer and price vary so much.

I think StemCells21 - 50,000,000 MSC or 100,000,000 MSC (I don't know if it will be financially successful).

I thought about Innate Healthcare because it is cheaper and offers more stem cells, but probably only StemCells21 is tested by forum users.

 

[James Connelly]

@SmallRonnie, I had a call with Innate Healthcare recently. They said they will look into either developing a drop with stem cells in it to go into the ear or an injection to the back of the ear.

 

[VTae]

This study shows how NGF improved hearing and tinnitus in people when injected just behind the ear.

Seems like this study has some really weird pseudo-science paragraphs though, not sure if it is trustworthy:

TCM theory holds that the function of internal organs is an expression of physiological activities and pathological changes. Channels and collaterals are passages to connect the internal organs and limbs, circulate the qi and blood, and communicate the exterior with the interior.

BDNF is also the drug they use in OTO-413.

Interesting, how do you know? I thought it was private info?

 

[SmallRonnie]

Seems like this study has some really weird pseudo-science paragraphs though, not sure if it is trustworthy:

It's translated from Chinese so maybe that's why it seems off.

Interesting, how do you know? I thought it was private info?

It's on their website.

 

[SmallRonnie]

I think StemCells21 - 50,000,000 MSC or 100,000,000 MSC (I don't know if it will be financially successful).

I thought about Innate Healthcare because it is cheaper and offers more stem cells, but probably only StemCells21 is tested by forum users.

@KotaDomowa, have you gone to get stem cells or are you going to? @James Connelly, are you going to any of the stem cell clinics to get treatment?

I've been considering just going to StemCells21, potentially some time soon.

 

[Nick47]

Forget stem cells. Look at Dr. Shore's results.

 

[SmallRonnie]

Forget stem cells. Look at Dr. Shore's results.

Dr. Shore's device won't do anything for my noxacusis unfortunately.

 

[KotaDomowa]

@KotaDomowa, have you gone to get stem cells or are you going to? @James Connelly, are you going to any of the stem cell clinics to get treatment?

I've been considering just going to StemCells21, potentially some time soon.

I haven't been yet. I am at the stage of looking for a better job to deal with the loan for this purpose.

Forget stem cells. Look at Dr. Shore's results.

I hope Dr. Shore's device will work very well. The question is also when it will be commercialized. At the moment, however, it is difficult to convince me even with the best results after my disappointment with Lenire and Otonomy.

But of course, I don't rule out trying Dr. Shore's device as well

 

[SmallRonnie]

I haven't been yet. I am at the stage of looking for a better job to deal with the loan for this purpose.

I hope Dr. Shore's device will work very well. The question is also when it will be commercialized. At the moment, however, it is difficult to convince me even with the best results after my disappointment with Lenire and Otonomy.

But of course, I don't rule out trying Dr. Shore's device as well

If you only have tinnitus without hyperacusis or noxacusis, then I'd be very hopeful for Dr. Shore's device.

I'd still like to try Dr. Shore's device myself since I can hear my tinnitus over 70 dB, but the pain is next level torture.

 

[James Connelly]

@KotaDomowa, have you gone to get stem cells or are you going to? @James Connelly, are you going to any of the stem cell clinics to get treatment?

I've been considering just going to StemCells21, potentially some time soon.

I think I'm going to try Innate Healthcare, even if their cell count and price are insanely/worryingly cheap...

 

[SmallRonnie]

I think I'm going to try Innate Healthcare, even if their cell count and price are insanely/worryingly cheap...

Yeah, it does kinda seem too good to be true but it very well may be legit. I hope it goes well for you if you do decide to go for it.

 

[James Connelly]

Yeah, it does kinda seem too good to be true but it very well may be legit. I hope it goes well for you if you do decide to go for it.

Cheers mate.

The doctor said he's up for doing a jab into the back of my ear much like StemCells21 do.

 

[SmallRonnie]

The doctor said he's up for doing a jab into the back of my ear much like StemCells21 do.

That would be very good. If he really does have legit stem cells, then it could be one of the best treatments going. I'm just worried about the authenticity of his stem cells.

As someone else said, umbilical cord stem cells are illegal in the US and if he's willing to be doing that treatment, then you have to question what else is he risking.

It could be legit though too, very hard to know.

 

[James Connelly]

That would be very good. If he really does have legit stem cells, then it could be one of the best treatments going. I'm just worried about the authenticity of his stem cells.

As someone else said, umbilical cord stem cells are illegal in the US and if he's willing to be doing that treatment, then you have to question what else is he risking.

It could be legit though too, very hard to know.

Yeah, I've wondered that too but I also heard that apparently he gets around it because of state law in Arizona but I might just ask him outright. He's answered all of my many questions so I'm sure he'll be fine with answering that one.

 

[SmallRonnie]

he gets around it because of state law in Arizona

This is what he told me. There are other clinics in Arizona also offering similar treatment so maybe there is some truth to that. Unless they are all just scams lol.