I would be surprised if Frequency's therapy helped for hyperacusis. Maybe temper expectations for that symptom.
Frequency Therapeutics — Hearing Loss Regeneration
- Thread starter RB2014
- Start date
I would be surprised if Frequency's therapy helped for hyperacusis. Maybe temper expectations for that symptom.
If it helped the hearing loss, and possibly the tinnitus that would be a HUGE improvement for me.
Why not? Just asking. Maybe hyperacusis is somehow linked to hair cells and that stuff, too.
It is but the pain is likely caused by damage to the existing nerve fibers. Growing more won't fix that damage.
Two questions I had on Frequeny's therapy.
Would round hole delivery apply mean more of the drug is delivered to the higher frequency regions of the cochlea?
Has Frequency tried dosing lab animals 2 or more times? If so were there additional benefits or possible adverse reactions with a second dose?
Would round hole delivery apply mean more of the drug is delivered to the higher frequency regions of the cochlea?
Has Frequency tried dosing lab animals 2 or more times? If so were there additional benefits or possible adverse reactions with a second dose?
Member- Mar 16, 2017
- 102
- Tinnitus Since
- 10/15 got worse 11/16
- Cause of Tinnitus
- Earbuds, inner ear infection NHL and high frequency loss
Good questions my guess is the higher frequency hearing loss is better since easy for med to reach. I am sure they are thinking of everything. Keeping my fingers crossed!
- Mar 16, 2017
- 102
- Tinnitus Since
- 10/15 got worse 11/16
- Cause of Tinnitus
- Earbuds, inner ear infection NHL and high frequency loss
https://www.laboratoryequipment.com/article/2017/05/humans-have-questions-nature-has-answers
Talks about FxT... not sure if this has been posted I like the approach!
Talks about FxT... not sure if this has been posted I like the approach!
Iliasp
Member
- Apr 26, 2017
- 65
- Tinnitus Since
- 03/2017
- Cause of Tinnitus
- Acoustic trauma, Hearing loss
More support for research just announced! Frequency Therapeutics is mentioned.
https://www.bostonglobe.com/metro/2...-initiative/SP8XvuilfFtSeRb1R4XOcJ/story.html
https://www.bostonglobe.com/metro/2...-initiative/SP8XvuilfFtSeRb1R4XOcJ/story.html
Edit: sorry for the typos. I meant to ask at what point do they believe that the treatment will be available to the public to actually use? Do they have any projections? I have been trying to read through the tread, but haven't seen this mentioned. They must have some predictions on when it will be available to the public.
Also, this is supposed to restore all types of noise induced hearing loss right?
I just need some hope in my life that they will be able to restore hearing loss.
Also, this is supposed to restore all types of noise induced hearing loss right?
I just need some hope in my life that they will be able to restore hearing loss.
No projections, but it looks really promising. I'd say 6 years if all goes well, maybe less. From what I have read this treatment looks like its right up your alley JD. This is about as good as it gets for you.
For me, I'm probably too far gone to benefit from it, especially in the 2k to 8k range, since those hair and supporting cells are probably over 90 percent gone.
- May 7, 2015
- 1,051
- Tinnitus Since
- 29.09/2014
- Cause of Tinnitus
- Acoustic trauma using headphones
Me to jdj09. But I´m afraid it´s too early to answer any of your questions.
Me, I´m very optimistic about this trial and they will probably start within a year.
There are reasons to be optimistic
- Mar 16, 2017
- 102
- Tinnitus Since
- 10/15 got worse 11/16
- Cause of Tinnitus
- Earbuds, inner ear infection NHL and high frequency loss
Why do think 90 percent is gone? How much loss do you have? Is it severe loss? Do you qualify for CI?
- Jul 19, 2015
- 70
- Tinnitus Since
- 1999 / Hyperacusis since 2012
- Cause of Tinnitus
- Acustic trauma
If i understand well, according with PROGENITOR CELL ACTIVATION (PCA™)
" The body has an innate, but sometimes dormant ability to heal itself. "
also
"Our first indication in hearing loss has produced positive results in preclinical studies, and we look forward to presenting further information as we move our lead program ahead."
Most of us in the high frequencies may be more or less in that percentage range and everyone expect a solution.....
So, do not loose yourself hope!
I have moderate to severe loss in the right ear and moderate to profound in the left. Approx 50db losses below 1k and 60 to 110db losses above 1k. From what I have read that may be too much to bring back using this type of procedure.
- Mar 16, 2017
- 102
- Tinnitus Since
- 10/15 got worse 11/16
- Cause of Tinnitus
- Earbuds, inner ear infection NHL and high frequency loss
Year from now do you think if trail starts will you try anyway. You might be able to bring some of your hearing back maybe not all. Worth a shot!!!!
What's the limit? I have 50 dB loss in one ear. Is this procedure not supposed to be effective for this level of loss?
Across all frequencies or a couple? I'd think that would be okay, it falls under moderate.
From my talks with Will McClean on /r/tinnitus, if your hearing loss is from dead/damaged haircells and you still have supporting cells then their treatment will work on you. The dB loss doesn't matter if you still have the supporting cells.
It was a coincidence that I found him on Reddit and there's a lot of other Tinnitus/hearing loss researchers on Reddit so I'm trying to get in touch with them too and smooth out some other questions that we have.
I got the exact quote from him. If you have mild to moderate hearing loss you still have supporting cells and Frequencytx treatment will work. If you have profound hearing loss then you don't have anymore supporting cells and the treatment won't work.
Thanks @NatureHiker. That is so cool that he's on reddit and open to talking with you. Anyway I hope their treatment works. I'll be thankful as I know many others will be for ANY degree of restoration! If I had known the sense of hearing was so fragile, I would have been a lot more careful with it.
Fabrikat
Member
- May 1, 2017
- 416
- Tinnitus Since
- 1973
- Cause of Tinnitus
- Otosclerosis then volume then viral infection
@NatureHiker, are supporting cells frequency specific? If one has mild to moderate hearing loss up to 8khz, but likely more profound loss over 8khz, does that mean that only hair cells below 8khz may be able to be regenerated, but above that nothing will regenerate. Or will it mean that if one has any treatable supporting cells, in any frequency region, then all frequencies may be restored?
Iliasp
Member
- Apr 26, 2017
- 65
- Tinnitus Since
- 03/2017
- Cause of Tinnitus
- Acoustic trauma, Hearing loss
Still hoping for some kind of imaging diagnostics in a cellular level so that all if these questions can be answered
By the time frequencys approach wont use up all the supporting cells for regeneration but will replicate them maybe multiple treatments is some kind of possible solution?
By the time frequencys approach wont use up all the supporting cells for regeneration but will replicate them maybe multiple treatments is some kind of possible solution?
Some more information about frequency Therapeutic
http://www.hearingreview.com/2017/0...enitor-cell-activation-technology-conference/
http://www.hearingreview.com/2017/0...enitor-cell-activation-technology-conference/
- Nov 8, 2016
- 45
- Tinnitus Since
- 2011
- Cause of Tinnitus
- don't know, hearing loss related?
I don't know what the criteria will be for the trials, but if there is a good chance of success then I will go for it. If it is more of an experiment to see what different dosages do to you, then I will probably pass.
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