Aleksa Uzunovic
Member
- Apr 2, 2019
- 43
- Tinnitus Since
- 2014
- Cause of Tinnitus
- Noise induced hearing loss
That's probably most of us. If fixing our high frequency hearing loss is all we need to stop the ringing, ohhhh baby...I think that if anything we will have high frequency hearing loss treated at first. That's awesome because that's what's damaged when the ears are exposed to excessive noise.
Not really.I think that if anything we will have high frequency hearing loss treated at first. That's awesome because that's what's damaged when the ears are exposed to excessive noise.
Do you have hearing loss in the range of 250 and 8000 Hz, between 25-70 dB?I submitted my audiograms. They said I didn't qualify, which is confusing because I have high frequency hearing loss. When I asked what the exclusion criteria was, they wouldn't tell me. Fuck them and their bullshit.
It's on the trial page: hearing loss in the 250-8000 Hz range, between 25-70 dB. There are also other exclusion criteria like no substantive conductive hearing loss.Did anyone find out what the exclusion criteria was?
The problem is not the drug but the delivery method. And that's easier to figure out than drugs to regrow hair cells. Should nanoparticles become an option we stand a good chance of reaching the lower frequencies.My hearing loss occurs between 250 Hz and 1000 Hz. I've remained hopeful. I'm so sad knowing this may not even be an option for me.
I had to click the "funny" rating because the same thing happened to me. It's so annoying they won't even tell you the required loss. Like what are we going to do? Go bang on pots and pans and try to get that? What's the big secret here? Nobody can control their audiogram.I submitted my audiograms. They said I didn't qualify, which is confusing because I have high frequency hearing loss. When I asked what the exclusion criteria was, they wouldn't tell me. Fuck them and their bullshit.
My biggest loss is 35 dB at 6000 Hz, and my main constant tone is 15000 Hz. I was still denied.Very interesting! Looks like they settled on this being only effective for 3500-16000 Hz. It even says FX-322 is "designed for higher frequencies". No it's not, it's a cope. That's a big chunk of hearing they are leaving out. That sucks...
I can bet $10,000 that tinnitus is triggered by high frequency hearing loss, for me at least that definitely is the case.That's probably most of us. If fixing our high frequency hearing loss is all we need to stop the ringing, ohhhh baby...
That's 10-15 dB from what's considered normal in one frequency. I can imagine Frequency is looking for patients that most represent their (intended) patient population; hearing loss across the board, with a downward slope in the high frequencies.My biggest loss is 35 dB at 6000 Hz, and my main constant tone is 15000 Hz. I was still denied.
HF sound waves carry the most energy so even at the same amplitudes, HF is more destructive.I can bet $10,000 that tinnitus is triggered by high frequency hearing loss, for me at least that definitely is the case.
I think the drug molecules they are using count as nano size.Should nanoparticles become an option we stand a good chance of reaching the lower frequencies.
It is interesting that they are stating right after their IPO that "FX-322 designed to enable hearing in higher frequencies". If they mean that it works for higher frequencies but not lower then it narrows down hugely the therapeutical range and market potential. I wonder if they disclosed that in the IPO prospectus. If not, you can ask if investors were misled.Very interesting! Looks like they settled on this being only effective for 3500-16000 Hz. It even says FX-322 is "designed for higher frequencies". No it's not, it's a cope. That's a big chunk of hearing they are leaving out. That sucks...
My biggest dip is 55 dB at 1000 Hz and the gal said by the audiograms I sent them that this fits into what they are looking for, for the phase 2 trial. Hopefully I can get past the next round of testing.Very interesting! Looks like they settled on this being only effective for 3500-16000 Hz. It even says FX-322 is "designed for higher frequencies". No it's not, it's a cope. That's a big chunk of hearing they are leaving out. That sucks...
Well, it could also be nerve or synapse damage. Supposedly the synapse miraculously regrows if a hair cell is there.I can bet $10,000 that tinnitus is triggered by high frequency hearing loss, for me at least that definitely is the case.
Even if you can't get an official extended audiogram this should give you an idea. There is a reproducible point where it goes from audible to immediately silent when I test with this and it corresponds to my steep slope on extended audiogram. May be harder to tell with more subtle loss though.Has anyone with normal hearing but believe they have high frequency hearing loss (or confirmed with an audiogram) reached out?
Ohh baby yes please. All I have is high frequency hearing loss above 12 kHz (and matching high frequency tinnitus) and if fixing hearing stops tinnitus, I'll be set.That's probably most of us. If fixing our high frequency hearing loss is all we need to stop the ringing, ohhhh baby...
I did. Confirmed at Stanford. Rejected from FX-322 study.Has anyone with normal hearing but believe they have high frequency hearing loss (or confirmed with an audiogram) reached out?
I agree that can be a cause.I can bet $10,000 that tinnitus is triggered by high frequency hearing loss, for me at least that definitely is the case.
Yes, I did. If you want the stock Tinnitus Talk members, better buy it now. It's already up over 10% from the IPO! The upgrades should move it up even more...Anybody buy any FREQ stock?
Got immediately upgraded by four investment houses. Good news for ears; maybe for the pocketbook too.
Interesting... thanks. Where did you find this quote?I found this quote from the main Audion guy:
But Jan Rutten is adamant that he is far from declaring Audion anywhere close to a eureka moment just yet. "Before you hear me claim such a thing, I think it is really important to do the clinical research," he says. "I think the biggest disservice that we can do to the field is to project unrealistic expectations," he says. There's a lot of good scientists at a lot of different companies doing the work, and "hopefully we'll come up with something."
I don't know if he was aiming this at Frequency Therapeutics but I think it applies to them. FX-322 may eventually be a working treatment (I hope so), but I do believe they declared their "eureka moment" much too soon.
Interesting article. Curious what this means for their Phase 2 results.I found this quote from the main Audion guy:
But Jan Rutten is adamant that he is far from declaring Audion anywhere close to a eureka moment just yet. "Before you hear me claim such a thing, I think it is really important to do the clinical research," he says. "I think the biggest disservice that we can do to the field is to project unrealistic expectations," he says. There's a lot of good scientists at a lot of different companies doing the work, and "hopefully we'll come up with something."
I don't know if he was aiming this at Frequency Therapeutics but I think it applies to them. FX-322 may eventually be a working treatment (I hope so), but I do believe they declared their "eureka moment" much too soon.