Everyone got the shot already, they'll do it immediately after the screening.
Frequency Therapeutics — Hearing Loss Regeneration
- Thread starter RB2014
- Start date
Member@Deathtotinni was travelling to SAT last week, he was supposed to have the screening on Wednesday and the injection on Thursday.
For some reason we haven't seen him online... And he used to get to the site daily. This worries me.
For some reason we haven't seen him online... And he used to get to the site daily. This worries me.
He said he wanted to take a break from it all and focus on the trial.
Besides he probably signed an NDA so we won't know much.
He without a doubt signed an NDA. This idea is worth trillions if all the potential applications of the technology are realized. Every single military in the world is gonna want in on this if it's successful.
Perhaps, but he could at least tell us that he signed one and that he isn't allowed to talk about it at all.
Like I told you I was disqualified but I went through the whole process...
I signed all documents. There wasn't an NDA. I think something went wrong with him...
One member from here sent him $250 and come on... He should come back to say thanks at least...
I only hope he's doing OK. He was all stressed out before the trip.
Coleoptere
Member
Correct, FX-322 will generate/duplicate progenitor cells which will in turn generate both inner and outer hair cells.
I wouldn't be surprised if this drug works that it will help with tinnitus & hyperacusis.
Man I really hope so. A coworker invited me to his church and I went today and the PAs were so frigging loud I had to leave. Plus the pastor was an obvious buffoon. I definitely have hyperacusis. And what is strange is I have more hearing loss and more tinnitus in my left ear and more hyperacusis in my right ear.
I expect this drug to decrease tinnitus and recruitment according to the hypothesis I subscribe to, but I am skeptical about it helping painful hyperacusis.
Nathan
Member
- Jul 28, 2018
- 164
- 23
- Tinnitus Since
- 06/2018
- Cause of Tinnitus
- Loud Music, Concert, Bad Luck
This seems unlikely, but what if the brain changes the frequency that you hear to be at the top of your hearing spectrum, and it is super loud?
I feel you man. I've had to pass on many offers to go to concerts or the club (even with earplugs it isn't worth the risk of making it worse), where I know I would have had a blast! Many, many fun opportunities I've missed because of tinnitus & hyperacusis.
But with all of these new developments in the industry I can definitively say that there is light at the end of the tinnitus treatment tunnel and it will be sooner than expected. Within a couple years we will at least have an effective treatment if not the pathway to a cure.
Even if the noise isn't loud, hyperacusis is felt at certain frequencies of hearing loss where the "gain" has been turned up to make up for the difference. So that gives me hope that replacing the hair cells (input) will return the "gain" to normal levels which should theoretically help.
I understand why you think tinnitus could then possibly move up on frequency, but I don't see any reason why it would get louder. I think it would only get quieter (generally, of course).
Otomagnetics - A New Drug Delivery System with Potential to Treat Hearing Loss
"There is potential to use this as a mode of delivery for the upcoming Frequency Therapeutics treatment drug called FX-322: http://www.frequencytx.com/news-events/news-events-press-release-10-4-2018.php"
"There is potential to use this as a mode of delivery for the upcoming Frequency Therapeutics treatment drug called FX-322: http://www.frequencytx.com/news-events/news-events-press-release-10-4-2018.php"
So while all this is happening, Frequency Therapeutics has a good reason to believe that the hair cells can be restored. It all just depends on their ability to enhance the synaptic connections that would be made.
Coleoptere
Member
From earlier publications from Frequency Therapeutics it was stated that the new hair cells were able to attract and connect to nerve cells.
And I assume they tested it pre-clinical.
Nevertheless I agree with your statement.
And I assume they tested it pre-clinical.
Nevertheless I agree with your statement.
I believe the same thing. It's all about enhancement. There is a true chance that the PCA treatment would work because it reverts the ears kinda back to their infancy stage. If it's as "natural" as they say, everything should sort itself out.
I think he's referring to an old email between someone and Jeff Karp. Wouldn't be that surprising considering all the things that go wrong and corrects itself when we are in vitro.
That's me. I asked him this:
"But I would like to ask you if your method will also repair/regenerate the auditory nerve/connections from the nerve to the hair cells?"
Mr Jeff Karp responded:
"Thank you for the note - we have some evidence to suggest the answer to that question is yes - but only time will tell as we push things forward
with warm regards,
Jeff"
with warm regards,
Jeff"
I meant to ask if you see it anywhere besides that Reddit post itself. It seems like the author of the post (who seems to be just a random Redditor) wrote it.
Ok. Gotcha. No, it looks to be just the observation/opinion of the poster. On the other hand, the Otomagnetics site says "these <magnetic> particles may be able to carry essentially any therapy (drugs, proteins, or genes)". FX-322 falls into the "any" basket so he really wasn't sticking his neck out too far.
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