Lenire — Bimodal Stimulation Treatment by Neuromod

[TibuJenkins]

I will only throw these two cents given that, contrary to what many others seem to think on these forums and this thread in particular of themselves, I AM NOT A SCIENTIST:

• This is something. It is not nothing. The technology has a lot of potential based on the publicly available information (taken at face value). But this creates hope, and hope is EXTREMELY dangerous for a tinnitus sufferer.
• Tinnitus and forums in particular seem to bring out the absolute worst in people. It's a big factor as to why many audiologists and ENTs who specialize in tinnitus literally beg you to avoid forums. I truly understand why now.

 

[AliceW]

In my mind, it will be released in May-June in Ireland and September-October in England, France, Belgium, Germany, Italy, Spain... etc...

They are now probably creating a partnership with one or two specialized clinics in each country where they will launch the device...

 

[TheDanishGirl]

I will only throw these two cents given that, contrary to what many others seem to think on these forums and this thread in particular of themselves, I AM NOT A SCIENTIST:

• This is something. It is not nothing. The technology has a lot of potential based on the publicly available information (taken at face value). But this creates hope, and hope is EXTREMELY dangerous for a tinnitus sufferer.
• Tinnitus and forums in particular seem to bring out the absolute worst in people. It's a big factor as to why many audiologists and ENTs who specialize in tinnitus literally beg you to avoid forums. I truly understand why now.

What? Hope is not dangerous. It is extremely important for a tinnitus sufferer. False promise on the other hand... That's dangerous! Which is why one must not get carried away about these things, but having some form of hope is vital... At least if one ain't habituated, like me.

 

[Nics2drescue]

It was mentioned in the Questions and Answers video by the CEO Ross O'Neill that they will release it in Ireland first, other European countries to follow later.

OK. I missed that part. Anyway my point was more so for those who don't live in Ireland, it's not a case where it's going to be a lifetime away from releasing internationally. So to give them more hope.

 

[Redknight]

What does clinically significant actually mean in Neuromod terms?

It just means that the result had a positive affect on the user's life.

The quote was something like 80% saw an effect, whilst 66% were clinically significant. What that means to me, is that 66% is the number we should care about, the other 14% felt a change so small it didn't affect their lives positively.

Still, 66% is great and we still don't know what would happen if a user used the device for 6, 12 months etc.

There's also a lot more to dialing in of frequency etc. The research has shown that that really is an art.

For most, seriously affected tinnitus sufferers, they would trade an hour a day using a device if it kept tinnitus down.

 

[hans799]

I would call it multi-tonal

I think multi-tonal is when you have two different eeeeees, or an eeeee and a bzzzt. So you can have a sound that's tonal, another sound that's also tonal, and a third sound that's atonal, and taken together, your tinnitus is multi-tonal.

 

[EDDTEKK]

What I am still wondering is that they claim or have witnessed that the tonality or atonality etc. doesn't matter in relation to the treatment effect.

But I have read so many reports by scientists about tinnitus and neuromodulation etc. They mostly claim that all these different types of tinnitus noises have a complete different brain pathology and hence mechanism. Until now, nobody could give any conclusive statement to this.

Just remember the Vagus Nerve Stimulation paired with sounds (Serenity Device) by the UT Texas at Dallas (Kilgard). That works only for tonal tinnitus (but even that treatment does not work for all patients).

Tinnitus is such a strange thing and can have so many pathological differences what causes it.

 

[GlennS]

I don't think anyone truly knows exactly why the bimodal stimulation works. It's like they are getting a beneficial result and then trying to explain why it works after the fact, but it's all still a theory. It's possible that focusing the frequencies around your actual tinnitus frequencies might be better, but they haven't tried doing that so they don't know for sure. I think it would be a good idea on their part to run more trials with different approaches like this so we'd know but for now they are using more of a one-size-fits-all approach.

 

[Jack Straw]

 

[Jack Straw]

• Tinnitus and forums in particular seem to bring out the absolute worst in people. It's a big factor as to why many audiologists and ENTs who specialize in tinnitus literally beg you to avoid forums. I truly understand why now.

The only thing this forum has shown me is that the mass majority of doctors and audiologists know nothing about tinnitus.

 

[Allan1967]

Does anyone know what would exclude someone from using Lenire?

 

[Helheim]

Does anyone know what would exclude someone from using Lenire?

I'd guess hearing loss that's so severe that you can't hear the audio component of the treatment would do the trick.

 

[JohnAdams]

Does anyone know what would exclude someone from using Lenire?

It not being released?

 

[JohnAdams]

I AM NOT A SCIENTIST

Yes you are.

 

[KotaDomowa]

I am still interested in how they understand the exclusion criteria: somatic tinnitus arising from head or neck injury. Do they mean accidents (violent injury) or also, for example, discopathies? And why were people from TMJ excluded?

 

[Allan1967]

It not being released?

Seriously... there has to be exclusion criteria.

 

[JohnAdams]

Seriously... there has to be exclusion criteria.

I'm sure you're right but they are being tight wads with info. Maybe their investors are getting cold feet because of stuff like hearing regeneration.

 

[jmasterj]

I'm sure you're right but they are being tight wads with info. Maybe their investors are getting cold feet because of stuff like hearing regeneration.

It does make you wonder, but they should have a good couple of years before hearing regeneration drugs and the other bimodal devices hit the market.

They have already invested so much you'd think they get what they can now while they are first to market.

 

[Bndsmheowqhe]

Does anyone know what would exclude someone from using Lenire?

$.

 

[jay777]

Does anyone know what would exclude someone from using Lenire?

££££££.

 

[DaveFromChicago]

I got this either from:
1) A viral particle from a severe head cold that migrated down the Eustachian Tube into the inner ear and/or aural nerve;
2) Severe inflammation over an extended period that perhaps stretched some area of tissue so much that it never quite returned to its original position.

Would this affect my eligibility for the Lenire treatment?

 

[GlennS]

I don't give a rat's ass whether Neuromod "lied" about release dates or not. At whatever point I hear a flood of positive testimonials from the field, I'm gambling my money on the thing and not looking back!

If some of you are so principled in your outrage over Neuromod's PR then feel free to stay on the sidelines and suffer. After all, you wouldn't want to reward Neuromod for "lying" to us, would you?

Oh, you won't? You mean you'll do a 360' and buy-in if that happens? Oh, really? Then why not spare us the memes and show a little patience?

 

[dayma]

I don't give a rat's ass whether Neuromod "lied" about release dates or not. At whatever point I hear a flood of positive testimonials from the field, I'm gambling my money on the thing and not looking back!

If some of you are so principled in your outrage over Neuromod's PR then feel free to stay on the sidelines and suffer. After all, you wouldn't want to reward Neuromod for "lying" to us, would you?

Oh, you won't? You mean you'll do a 360' and buy-in if that happens? Oh, really? Then why not spare us the memes and show a little patience?

Preach it man!

Agreed. I am suffering just like everyone else but nothing that has been done in the last 6 months has dissuaded me from wanting to buy the product. Just waiting to tell me when and where and I am good.

 

[grate_biff]

Oh, you won't? You mean you'll do a 360' and buy-in if that happens?

That´s 180' Glenn...

 

[Karl28]

• This is something. It is not nothing. The technology has a lot of potential based on the publicly available information (taken at face value). But this creates hope, and hope is EXTREMELY dangerous for a tinnitus sufferer

"Hope is a good thing, maybe the best of things, and no good thing ever dies." — Andy Dufresne.

 

[Helheim]

That´s 180' Glenn...

I think the whole "turn 360" thing is a meme from the good old Xbox days.

Anyway. Sooner or later this shit will have to come out. C'mon, Neuromod.

 

[GlennS]

That´s 180' Glenn...

Yep. My bad.

 

[kelpiemsp]

Seriously... there has to be exclusion criteria.

Hyperacusis. And if you believe that headphone use will make your tinnitus worse, then it probably isn't for you.

 

[Paulmanlike]

Can't wait just to read the paper on the TENT-A1 that should be published any day now.

The paper on the TENT-A2 will probably not be out until the end of the year (as the study hasn't concluded yet and the peer review takes up to 6 months).

I hope they have determined the best 'arm' to use and that's what we will be doing once we are using this product.

Damn this high pitched noise in my head, can't wait to retrain my brain and calm down the neurons and drive some plasticity.

 

[GSC]

Hyperacusis. And if you believe that headphone use will make your tinnitus worse, then it probably isn't for you.

People with hyperacusis were super-responders though.