Lenire — Bimodal Stimulation Treatment by Neuromod

#3,811
I'm beginning to wonder if using Nootropics such as Noopept or Piracetam while undergoing the 10-12 week treatment with Lenire would improve results extensively.

Noopept increases brain plasticity and NGF and BDNF to great extents (greater than Curcumin as well), resulting in neurogenesis. If Lenire is based around neuroplasticity, perhaps then the results can be potentiated by using nootropics in conjunction with bimodal stimulation.
 
#3,814
ChrisBoyMonkey said:
It's a limited contract. He'll be going back to the University of Minnesota after it's up. I don't think he'll be racing to get his treatment out though.
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Go check out the University of Minnesota thread. I can't remember all the details, but it's been discussed there. I believe he is back in Minnesota, but not currently continuing his research on their device. He plans to, but they are taking a pause on the trials. Somebody contacted him to get this info.
 
#3,817
ChrisBoyMonkey said:
It's a limited contract. He'll be going back to the University of Minnesota after it's up. I don't think he'll be racing to get his treatment out though.
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How do you know that the contract was limited? Is there any article about that? So Neuromod just hired Hubert Lim for promotion activities or did he really give some advice for the settings and treatment design?

This news on the website of Neuromod sounds that he settled with his familiy in Ireland to support Neuromod long-term, doesn't it?

https://www.neuromoddevices.com/new...-of-dr-hubert-lim-as-chief-scientific-officer
 
#3,818
EDDTEKK said:
How do you know that the contract was limited? Is there any article about that? So Neuromod just hired Hubert Lim for promotion activities or did he really give some advice for the settings and treatment design?

This news on the website of Neuromod sounds that he settled with his familiy in Ireland to support Neuromod long-term, doesn't it?

https://www.neuromoddevices.com/new...-of-dr-hubert-lim-as-chief-scientific-officer
Click to expand...
As stated above, check the University of Minnesota thread. I think someone reached out and that was the response.
 
#3,819
I have come to the conclusion that Lenire is spiking my tinnitus.

When I first got it my tinnitus started increasing and the reactivity went mental, that's when I was using it twice a day.

Then I dropped to once a day and it eased slightly. Then I stopped for a couple of days and the following days were much more tolerable.

Then I tried again last night, went straight to sleep, woke up at 3 am and my tinnitus was just dreadful. So I'm now quitting until I get there next week and get this hiss removed hopefully.

The other sounds are much more gentle and at low volume much easier to tolerate.
 
#3,820
On the phone to Neuromod today. Have to admit they bend over backwards to help... contacting people who are on leave to get answers, always polite and nothing is too much trouble.

They are changing my signal timing next week AND have a range of options at their disposal in terms of the music that I can listen to and choose so I leave happy.

Which is good if heavy rain/white noise aggravates you. I'm looking for something soft and gentle, not too high pitched.
 
#3,822
Allan1967 said:
On the phone to Neuromod today. Have to admit they bend over backwards to help... contacting people who are on leave to get answers, always polite and nothing is too much trouble.

They are changing my signal timing next week AND have a range of options at their disposal in terms of the music that I can listen to and choose so I leave happy.

Which is good if heavy rain/white noise aggravates you. I'm looking for something soft and gentle, not too high pitched.
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Seems to prove that they are truly overwhelmed with the number of patients but are focusing on the patients that have units. Positive indeed. Hope the new setting helps you out!
 
#3,823
spedgas said:
Go check out the University of Minnesota thread. I can't remember all the details, but it's been discussed there. I believe he is back in Minnesota, but not currently continuing his research on their device. He plans to, but they are taking a pause on the trials. Somebody contacted him to get this info.
Click to expand...
IDK, I e-mailed him earlier this year at his University of Minnesota address listed here:
http://soniclab.umn.edu/

He said they would do more trials just not any time soon (I can wait, honestly, but would like to participate). He'll probably respond to reasonable questions but ehh I'm ambivalent about further bugging this bonafide celebrity.

He's still an associate professor at the department of biomedical engineering and is also transparent about his financial interest in Neuromod. Not sure if he has to square any circles regarding potential conflicts of interest about his research.
 
#3,824
Fifth Business said:
IDK, I e-mailed him earlier this year at his University of Minnesota address listed here:
http://soniclab.umn.edu/

He said they would do more trials just not any time soon (I can wait, honestly, but would like to participate). He'll probably respond to reasonable questions but ehh I'm ambivalent about further bugging this bonafide celebrity.

He's still an associate professor at the department of biomedical engineering and is also transparent about his financial interest in Neuromod. Not sure if he has to square any circles regarding potential conflicts of interest about his research.
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Also, recently they were recruiting engineers to actually create a wearable device. I'm sure that is going to take some time. I would love to participate in this trial since I live relatively close. I just don't know if I can wait that long so that is why I am going to Ireland in November.
 
#3,827
Allan1967 said:
On the phone to Neuromod today. Have to admit they bend over backwards to help... contacting people who are on leave to get answers, always polite and nothing is too much trouble.

They are changing my signal timing next week AND have a range of options at their disposal in terms of the music that I can listen to and choose so I leave happy.

Which is good if heavy rain/white noise aggravates you. I'm looking for something soft and gentle, not too high pitched.
Click to expand...
You are in good hands Allan!

I expressed my suspicions from day one if we will get the same level of professionalism and knowledge from clinics other than Neuromod. I wouldn't trust much anyone else.
These people are interested in making their product work, not just collection of money.

You can at least rest assured that you are getting the best of what's available for now.

Good luck and stay hopeful!
 
#3,829
EDDTEKK said:
I'm just wondering for what reason they play these sounds? It seems it is not mandatory, and the sound quality seems to not have any reason, no?
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OK I found this comment:

"Further studies in the lab have revealed that paired acoustic stimulation (e.g., broadband noise) with electrical stimulation of the trigeminal nerve, including the ear and tongue, can drive strong plasticity within the auditory system relevant for tinnitus treatment."

http://soniclab.umn.edu/research/neural-beamforming-tinnitus
 
#3,831
I don't think it is the same, since the approach in the University of Minnesota has Olfactory, Gustatory, Visual and Auditory Stimulation paired, if I understand the picture on the page correctly.

Just wondering why they didn't include also haptics as another stimulus.

However, it sounds that bimodal stimulation alone will also do something on the auditory system.
 
#3,832
dayma said:
I don't think anyone knows how the timing compares. Michigan published theirs at one point but I never saw Neuromod's or Minnesota's. The timing is the key to all of this and why the DYI stuff fails mostly.
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I know Lenire didn't do this, but part of the reason the treatment was so successful for me, IMHO, is because Minnesota ran an EEG while developing a timing starting point. Kind of like a golf handicap specific to my brain. I think ultimately they may offer a customized treatment that is programmed to both your hearing level and the speed at which you uniquely process.
 
#3,833
Not sure why people are so worried about conflict of interest? The University of Minnesota has rights to X percent of profit on patents from their professors. They would want Neuromod to succeed. And also Neuromod could use their resources to conduct trials in the US. It's very likely a symbiotic relationship. That's also why trials in the Minnesota study would resume.
 
#3,836
I don't remember where I read it, but Neuromod's methods were based on the studies done and published by Hubert Lim at the University of Minnesota. I believe the device that Minnesota is using is stimulating the ear versus the tongue. I am guessing that is more for convenience instead of having to hold a device in your tongue for an hour a day.
 
#3,837
AliceW said:
But is Lenire also based on this same multimodal synchronization as the University of Minnesota's device? (Is the bimodal stimulation the same process?)
Click to expand...
Yes but that doesn't necessarily mean each device will be equally effective. The devil's in the details.

BTW, there is a key phrase in this page:

the type of plasticity elicited in the auditory system using mSync is greatly altered depending on the attention and stress levels of the animals.​

This backs up my "superstition" that your state of mind during treatment will be an important factor in how well Lenire works.
 
#3,838
Heinrich_S7 said:
I'm beginning to wonder if using Nootropics such as Noopept or Piracetam while undergoing the 10-12 week treatment with Lenire would improve results extensively.
Click to expand...
I was getting lithium orotate yesterday at a natural foods store and the guy in the supplements aisle recommended those exact 2 things and even wrote their names down for me.
 
#3,839
EDDTEKK said:
I don't think it is the same, since the approach in the University of Minnesota has Olfactory, Gustatory, Visual and Auditory Stimulation paired, if I understand the picture on the page correctly.

Just wondering why they didn't include also haptics as another stimulus.

However, it sounds that bimodal stimulation alone will also do something on the auditory system.
Click to expand...
The trial was sound and ear lobe. I was in it.
 

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