My Posting Place

[JohnAdams]

@Contrast or anybody else. Is central gain theory saying that quiet sounds get amplified which is why shitnitus gets louder in silence?

 

[IAmCalifornia]

View attachment 22119

meme status -> a m a z i n g

 

[IAmCalifornia]

 

[Contrast]

Anyone with a functioning brain should be aware there are two separate models of tinnitus and obviously one is probably wrong.





Central gain/phantom input hypothesis
(tinnitus is entirely generated in the brain from a lack of hearing input)
This hypothesis holds up and explains why tinnitus can be caused by anything from ear wax, middle ear malfunction and SNHL, if true it would put tinnitus in a larger category of conditions like phantom limb pain and chronic pain from nerve damage. NMDA causing neurological changes can still be true under this hypothesis.

_______________________________________________________
NMDA centric hypothesis
states that tinnitus is semi-peripheral and exclusively caused by NMDA hyperactivity in the audiotory nerve.

Ear plug experiments and audiotory nerve severations that result in tinnitus are not explainable using this hypothesis. They assume tinnitus is generated in the ear and then moves to the brain.

 

[Contrast]

Roland Schaette put a huge dent in there model with his ear plug experiments
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3366980/

.

Moving on to another paper about Cochlear Implants
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5339283/

and another

http://www.tinnitusjournal.com/articles/can-cochlear-implants-decrease-tinnitus.pdf

Moving on to this
https://blog.medel.com/cochlear-implants-tinnitus-cure/

(note these guys sell CI's and are a bit over enthusiastic)
however i took a deep look into it and found stories of people with CI's and realize what they are saying is true

 

[Manny]

@Contrast or anybody else. Is central gain theory saying that quiet sounds get amplified which is why shitnitus gets louder in silence?

@JohnAdams afaik Central gain theory states that the brain acts to compensate for missing sensory input. In our case, this is the brain's auditory system generating tinnitus due to reduced auditory input (due to HL).
I don't believe that this theory claims that tinnitus becomes objectively quieter in everyday silence.
But, I think it's an interesting line of thought, because even everyday silence means less input. A la Roland Schaette's earplug experiments mentioned above by Contrast above.

 

[Contrast]

this is the only known emoji that works on the website because
https://www.tinnitustalk.com/gift

uses it

 

[Contrast]

this one also works but most dont, i'm experimenting why

 

[JohnAdams]

 

[dpdx]

WHy is Contrast leaving?

 

[threefirefour]

View attachment 22160

Now this is genius

 

[Contrast]

Dont you mean will not?

OMG typo, I meant to say will NOT

 

[Manny]

I'm beginning to think the standard audiogram has done more bad than good for medicine at large.

 

[Manny]

If all these bad ENTs were neurologists we'd all be brain dead, just something to think about over your cornflakes

 

[85dB T]

If all these bad ENTs were neurologists we'd all be brain dead, just something to think about over your cornflakes

I actually have a "great" Neurologist/Otolaryngologist.

His office is usually young children or elderly.

I can see why no one is interested in us for obvious reasons.

Or maybe I should say: not interested in "not so obvious" illness, such as "auditory hallucinations".

 

[JohnAdams]

If all these bad ENTs were neurologists we'd all be brain dead, just something to think about over your cornflakes

If we lived in the 1950's they would have called our emotional reaction to tinnitus "psychosis" and given us lobotomies.

The original CBT.

 

[85dB T]

If we lived in the 1950's they would have called our emotional reaction to tinnitus "psychosis" and given us lobotomies.
View attachment 22164
The original CBT.

Post-birth abortion

 

[JohnAdams]

I don't even think you need a wnt activator like carrageenan. Looks like inhibition of notch does that already.

"We demonstrate that Notch inhibition removes the brakes on the canonical Wnt signaling and promotes Lgr5+ progenitor cells to mitotically generate new HCs (hair cells)"

http://www.pnas.org/content/112/1/166

 

[dpdx]

If all these bad ENTs were neurologists we'd all be brain dead, just something to think about over your cornflakes

ENTs are retards.
Audiologists here and there.

 

[dpdx]

View attachment 22119

RIGHT
HAHAHAAHAHAHAHA

 

[85dB T]

ENTs are retards.

A simple statement full of intellectual, hostile, aggressive, sarcastic, and cynical humor!

An ENT lecturing me on tinnitus is like a three year old telling an adult how to parent.

 

[Contrast]

as long as my noxacusis is gone and stays gone i'm probably not gonna off myself for atleast 5 years

5 years from now I'll make the decision based on bio tech's progress

 

[dpdx]

as long as my noxacusis is gone and stays gone i'm probably not gonna off myself for atleast 5 years

5 years from now I'll make the decision based on bio tech's progress

If my Severe T and Severe H persist and if there is no cure/treatment, and it has been 8 months or so, then I will perhaps go on the same route as you my friend. Having dark thoughts today this is not my usual self.

 

[85dB T]

noxacusis

Do you wear double ear protection, does this help?

 

[Contrast]

Do you wear double ear protection, does this help?

no, none. What's the point of living if I have to compensate like that?

 

[IAmCalifornia]

So, what do we have to look forward to in the future? Susan Shore + Frequency basically?

 

[85dB T]

no, none. What's the point of living if I have to compensate like that?

You must find your point of living. This is now your purpose. I promise it's out there. Look hard because it will be unlike everyone else's, it will be uniquely yours. You have dedication, devotion, loyalty and integrity. This I know about you. Rare qualities not to waste.

I know nothing about Noxacusis. I will read this article to better understand your suffering and your challenges.

https://www.statnews.com/2016/02/18/noise-induced-ear-pain/

Please forgive me if I have spoken out of place.

 

[Contrast]

Otonomy will start a trial for cochlear synapse damage in 2019 and Decibel is working on something.

 

[dpdx]

My T is a hiss today not a high pitched dentist drill,
it dropped from a 8/10 to a 6/10 (lowest it has been since January 14)
Thoughts? Will it stay that way or will it get better?

 

[dpdx]

H is still the same