My Posting Place

[Contrast]

Doesn't frequency therapeutics drugs repair hair cells along with ribbon damage? I'm pretty sure I read @JohnAdams discussing this.

Also the stimulation devices will most likely provide a much needed treatment until the cure it found. I know a cure is optimal, but a least a treatment is better than nothing. I am sure it will give a lot of us some quality of life back.

I believe new hair cells come with new ribbon synapses, but I am 99% certain damaged hair cells that still exist will stay damaged. Liberman's study showed hearing loss has more to do with ribbon synapse damage then hair cell damage.

I can still hear up to 15,000hz
meaning I have hair cells that are basically de-nerved, and the hope is that generating new ones will help, but according to @JohnAdams regenerated hair cells won't grow where current hair cells exist.


so my damage in low-high frequencies 1,000hz-10,000hz caused by cochlear synapse damage won't repair. and I'll just get my ultra high frequencies that are near useless restored. I'll still have trouble with speech in excessive background noise and most music.

I think a more effective treatment would be to repair the ribbon synapses of the cochlea, maybe both. That's the thing.

 

[Jack Straw]

I believe new hair cells come with new ribbon synapses, but I am 99% certain damaged hair cells that still exist will stay damaged. Liberman's study showed hearing loss has more to do with ribbon synapse damage then hair cell damage.

I can still hear up to 15,000hz
meaning I have hair cells that are basically de-nerved, and the hope is that generating new ones will help, but according to @JohnAdams regenerated hair cells won't grow where current hair cells exist.


so my damage in low-high frequencies 1,000hz-10,000hz caused by cochlear synapse damage won't repair. and I'll just get my ultra high frequencies that are near useless restored. I'll still have trouble with speech in excessive background noise and most music.

I think a more effective treatment would be to repair the ribbon synapses of the cochlea, maybe both. That's the thing.

Well until that is figured out we can use the stimulation devices. Remember that in the VAST majority of people who has hearing loss they don't develop tinnitus. This is because they brains have a natural "tune our" function and ours isn't working properly. Mutebutton is supposed to not only reduce tinnitus, but also help with H as well. This will help give us the time we need to more comfortably wait for a cure.

 

[JohnAdams]

because most hearing loss has to do with synaptic ribbon damage, regenerating hair cells may be useless for speech in background noise.

Dude bro, the Will McLean thing he says the ribbon synapses regenerated too. We just have to be patient.

 

[Jack Straw]

Just joking around @Deamon22 ! I'm happy your getting better, but sad we will lose another MPPer. I also poke fun at @threefirefour cuz I miss him. Lol

 

[Contrast]

Dude bro, the Will McLean thing he says the ribbon synapses regenerated too. We just have to be patient.

only where dead hair cells are.

the dead hair cell region pops up with new hair cells /ribbon synapses

but hair cells that are damaged will stay damaged.

 

[Manny]

only where dead hair cells are.

the dead hair cell region pops up with new hair cells /ribbon synapses

but hair cells that are damaged will stay damaged.

Source?

 

[Manny]

I hate all this wrangling with FX and Gene therapy and mild HL and severe HL and cells and nerves, just redo my entire g0ddamn head please.

 

[Manny]

CGF166 Gene therapy trial is using audiogram up to 16 khz! Hurrah finally some researchers emerging from the 250-8 khz Stone Age!!

https://clinicaltrials.gov/ct2/show/NCT02132130

ATTACH=full]23700[/ATTACH]

 

[Deamon22]

View attachment 23698
Just joking around @Deamon22 ! I'm happy your getting better, but sad we will lose another MPPer. I also poke fun at @threefirefour cuz I miss him. Lol

Haha thats fantastic. Well, the forum won't lose me since i will still follow the research and i also donate every month to TT and other funds.

And believe me, if i could do anything to eradicate this crap from the face of the earth, i would do it. I'd wish that no one needs to suffer from this.

 

[JohnAdams]

Haha thats fantastic. Well, the forum won't lose me since i will still follow the research and i also donate every month to TT and other funds.

And believe me, if i could do anything to eradicate this crap from the face of the earth, i would do it. I'd wish that no one needs to suffer from this.

Your tinnitus went away?

 

[Deamon22]

Your tinnitus went away?

Well it's at least 90% silence again i'd say. The actual good news this time around is that my mild T in my right ear, which i had since onset (tea kettle + high pitch whistling), went away 100%. That one actually was always kind of there the whole 5 months, also during my silent periods i heard that one in the morning and at night, but now it seems to be gone.

And that one was non somatic, i couldn't modulate it. I actually never thought that i would get rid of that.

 

[Manny]

I think those of us with NIHL, like me are more likely to have our T be permanent (barring a treatment or cure of course).
Aaaaarrrrgh why why why IS HL NOT HAD ENOUGH

 

[Deamon22]

I think those of us with NIHL, like me are more likely to have our T be permanent (barring a treatment or cure of course).
Aaaaarrrrgh why why why IS HL NOT HAD ENOUGH

Well i treat my T like noise induced, since i had my fair share of clubs, headphones and loud places over the years. There is no guarantee that mine is different. It just started with a cold, but maybe that was what finally broke the camels back. Who knows.

 

[Contrast]

 

[Contrast]

CGF166 Gene therapy trial is using audiogram up to 16 khz! Hurrah finally some researchers emerging from the 250-8 khz Stone Age!!

https://clinicaltrials.gov/ct2/show/NCT02132130

ATTACH=full]23700[/ATTACH]

>gene therapy
> no speeech in background noise

 

[Manny]

>gene therapy
> no speeech in background noise
View attachment 23705

At least progress but agree.

 

[Jack Straw]

 

[JohnAdams]

>gene therapy
> no speeech in background noise
View attachment 23705

I know de wey.

 

[Manny]

I know de wey.

 

[JohnAdams]

Well it's at least 90% silence again i'd say. The actual good news this time around is that my mild T in my right ear, which i had since onset (tea kettle + high pitch whistling), went away 100%. That one actually was always kind of there the whole 5 months, also during my silent periods i heard that one in the morning and at night, but now it seems to be gone.

And that one was non somatic, i couldn't modulate it. I actually never thought that i would get rid of that.

Nyesssss. From what we've discussed it seemed like out tinnitus cases were very similar. Today my shitnitus was ready subdued almost gone, again, also my hearing was really clear. I did eat curcumin sauce pizza for dinner. You give me hope i can recover man.

 

[Contrast]

someone test if this works in Google Chrome https://css-tricks.com/examples/SoundOnHover/ the audio should play if you hover over the button
make sure you are using chrome 71 (latest version)

 

[Manny]

WHY can't medicine get their act together, recognize T as a real ailment that needs more than TRT crap, do full hearing tests that are already available (e g. full range audiogram up to 16 or 20 khz) for diagnostics, and work on a cure based on that??
Why is the hearing diagnostic field so fcking backwards??? It's not that hard, actually!

 

[Manny]

When is the next official update from FX TX Co.?

 

[JohnAdams]

WHY can't medicine get their act together, recognize T as a real ailment that needs more than TRT crap, do full hearing tests that are already available (e g. full range audiogram up to 16 or 20 khz) for diagnostics, and work on a cure based on that??
Why is the hearing diagnostic field so fcking backwards??? It's not that hard, actually!

Why cant human civilization stop with the bullshit and cure all diseases including regenerating limbs? I bet if American alone stopped the war machine nonsense and the 1% donated 90% of their wealth that we could achieve this.

 

[JohnAdams]

When is the next official update from FX TX Co.?

probably December.

 

[Manny]

probably December.

Thanks, do you have a source for that? Or is that just the clinical trial scheduled end date?

 

[JohnAdams]

Thanks, do you have a source for that? Or is that just the clinical trial scheduled end date?

trial end

 

[threefirefour]

View attachment 23698
Just joking around @Deamon22 ! I'm happy your getting better, but sad we will lose another MPPer. I also poke fun at @threefirefour cuz I miss him. Lol

This meme is great.

Sorry I've been busy lately

 

[IAmCalifornia]

MPP has changed so much.

 

[threefirefour]

MPP has changed so much.

It really has. IDK what to make of it.

I think the biggest change was from being the site equivalent of outlaws to being somewhat accepted.