MemberTrial and error is how I decided to use it at night wile sleeping, and then I found studies like this.
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- Thread starter threefirefour
- Start date
Frequency Therapeutics Provides Business Updates and Reports Third Quarter 2019 Financial Results
November 18, 2019 7:30 AM
Initiated FX-322 Phase 2a clinical study for sensorineural hearing loss
Granted FDA Fast Track designation for FX-322
https://www.streetinsider.com/dr/news.php?id=16146493&gfv=1
November 18, 2019 7:30 AM
Initiated FX-322 Phase 2a clinical study for sensorineural hearing loss
Granted FDA Fast Track designation for FX-322
https://www.streetinsider.com/dr/news.php?id=16146493&gfv=1
You can download Tinnitus Mix at https://tinnitusmix.com
You must play on low with Koss KTX-PRO1 headphones (25 kHz) all night every night for 3 weeks to break the tinnitus.
It looks like Levo and other sound treatments, do have some potential in improving Tinnitus.. Levo is recommended to use while sleeping. I'm saying this, because the general consensus on this forum, was that these things only help in habituation and do not physically affect Tinnitus.
Tinnitus Mix sounds so intense. It's like a hard gym workout. I was so afraid of damaging my hearing by listening to this mix, that I would never try listening it for a few hours, if not for John Adams and his Tinnitus improvement in the last days.
Tinnitus Mix sounds so intense. It's like a hard gym workout. I was so afraid of damaging my hearing by listening to this mix, that I would never try listening it for a few hours, if not for John Adams and his Tinnitus improvement in the last days.
It is like a demonic chorus from Hell. My dog woke me up last night and I tried to fall back asleep while listening to it and I couldn't. It is truly heavy mental lifting. I've basically had to drink myself to sleep to tolerate it.
Yes Tinnitus Mix is harsh at first but will change into soothing sounds and help you sleep. Here is the typical response of the user:
Here is some sorta bad news:
So I was trying to track down how curcumin could be used to regenerate haircells and saw that it was a notch inhibitor, and notch inhibition is a process used in getting inner ear stem cells to grow into new hair cells.
The ultimate key here is through, wnt activation, notch inhibition, or whatever, to get something called beta-catenin to not be destroyed and enter into the nucleus. This is what causes the cell to transdifferentiate into a hair cell.
Well, I found out that curcumin actually lowers nuclear beta-catenin. So while it can lower tinnitus for some, it is not going to permanently improve hearing in any dose.
Also, and here is the bad news. Inducing beta-catenin levels to increase is what causes cancer to proliferate. Thus the need for the hair cell drugs to be delivered topically to the round window. This leads me to believe that anything that cannot be taken orally because of a risk of cancer, despite my previous belief that there was going to be a way to do this.
So I was trying to track down how curcumin could be used to regenerate haircells and saw that it was a notch inhibitor, and notch inhibition is a process used in getting inner ear stem cells to grow into new hair cells.
The ultimate key here is through, wnt activation, notch inhibition, or whatever, to get something called beta-catenin to not be destroyed and enter into the nucleus. This is what causes the cell to transdifferentiate into a hair cell.
Well, I found out that curcumin actually lowers nuclear beta-catenin. So while it can lower tinnitus for some, it is not going to permanently improve hearing in any dose.
Also, and here is the bad news. Inducing beta-catenin levels to increase is what causes cancer to proliferate. Thus the need for the hair cell drugs to be delivered topically to the round window. This leads me to believe that anything that cannot be taken orally because of a risk of cancer, despite my previous belief that there was going to be a way to do this.
How mental is cancer?
How mental is diabetes?
How mental is amputation?
How mental is HIV?
How mental is blindness?
How mental is necrosis?
How mental is ALS?
You are crazy dude. Stop lying to people to try and make them feel better.
I GOT IT.
Carageenan stimulates wnt/beta-catenin which is what we need to happen in our cochleas.
https://www.tandfonline.com/doi/abs/10.1080/01635581.2014.852228
Step 1:
Hang upside down
Step 2:
Insert a stint into your eustachian tube opening
Step 3:
Inject a solution of carrageenan into the stint
'
Step 4:
Sleep.
Step 5:
Repeat in other ear.
OR
Neti pot with a carrageenan solution.......
I'm not joking. I may try this.
Carageenan stimulates wnt/beta-catenin which is what we need to happen in our cochleas.
https://www.tandfonline.com/doi/abs/10.1080/01635581.2014.852228
Step 1:
Hang upside down
Step 2:
Insert a stint into your eustachian tube opening
Step 3:
Inject a solution of carrageenan into the stint
'
Step 4:
Sleep.
Step 5:
Repeat in other ear.
OR
Neti pot with a carrageenan solution.......
I'm not joking. I may try this.
Attachments
@JohnAdams
I thought you might want to correspond in a dignified and civilised manner but I see you haven't changed. Still using language from the gutter. I suppose it's true what they say: You can take the man out of the gutter but you cannot take the gutter out of the man.
In future when you wish to quote something that I have written, please have the decency to quote what I mean correctly. I said: Tinnitus is 90% mental. By this I mean it is intrinsically linked to our mental and emotional wellbeing. Of course, as you are someone that hasn't had tinnitus long and lack experience, you fail to understand what I mean. Tinnitus veterans like @fishbone do understand so please contact him and I'm sure he'll enlighten you and I promise, you'll feel a whole lot better and more knowledgeable about tinnitus.
Another thing. I realise you are not from the UK so hope you don't mind me saying, you have used the word bloke in the wrong context. @Jcb will bring you up to speed. It is not a word that I have ever used, as it's often spoken by certain types of people that have no interest in speaking English well.
All the best
Michael
No he knows what you meant by saying 90% is based on mental well-being, he just thinks you're wrong. Because it is.
- Feb 17, 2017
- 10,400
- Tinnitus Since
- February, 2017
- Cause of Tinnitus
- Acoustic Trauma
While I think I am on your side on this one, I understand where Michael is coming from. It is undeniable that some people aren't bothered by noise. Many people study while having music in the background, others hang up wind chimes. I bet that the people on this forum tend to not do any of that. Some people are on the fence as far as this intolerance to noise is concerned. They might be able to "get over it" and just learn to ignore the sound. Michael is probably talking about them. Of course many people simply can't do anything about their nature (which compels them to seek silence and to be unhappy when being exposed to noise).
- Feb 17, 2017
- 10,400
- Tinnitus Since
- February, 2017
- Cause of Tinnitus
- Acoustic Trauma
Mate I'm Dyslexic so I wouldn't be any type of authority on anybody's grammar, nor would I judge anybody either way. I'm surprised I manage to make any sense most of the time?!
Also if that's a attempt to "shade" my grammar and what "type" of person I am it's a weak attempt. I'm from good stock my man, like premium grade sh*@.
You wonder why you irritate so many people, it's funny.
Ps John did use the term "bloke" in the wrong term but who cares, like really?. Somebody who claims they were brought up the "correct" way you are one of the most judgmental people on here, suppose that's got something to do with your unfulfilled life but if I get into that I'd have to charge you top dollar.
I Wish you well Michael xx
- Jan 1, 2019
- 708
- Tinnitus Since
- Steadily worsening since 2018
- Cause of Tinnitus
- Unknown
@Jcb
Correcting someone grammar is not always a polite thing to do. It for this reason I said to @JohnAdams I realise you are not from the UK. I wouldn't write in an open forum the correct way "bloke" should be used as I believe that would be the height of bad manners and disrespectful. I am not an authority on English grammar either. As I said, it is word that is often spoken by certain types of people that I believe, have little regard for speaking English well.
Certain things do matter in this world especially when we meet someone for the first time or associate with certain people. We are immediately judged by the way we speak, our attire and the language we use. I am sure you wouldn't go for a job interview and shake someone's hand and address them as "Mate" as you did me.
All the best
Michael
Correcting someone grammar is not always a polite thing to do. It for this reason I said to @JohnAdams I realise you are not from the UK. I wouldn't write in an open forum the correct way "bloke" should be used as I believe that would be the height of bad manners and disrespectful. I am not an authority on English grammar either. As I said, it is word that is often spoken by certain types of people that I believe, have little regard for speaking English well.
Certain things do matter in this world especially when we meet someone for the first time or associate with certain people. We are immediately judged by the way we speak, our attire and the language we use. I am sure you wouldn't go for a job interview and shake someone's hand and address them as "Mate" as you did me.
All the best
Michael
Bloke would be something you would say like "he's a top bloke" or "that bloke over there is a right wank stain" you wouldn't use it in the context you did, if you used mate that would of been better or man. I'm not judging btw I barely write In compete sentences at the best of times.
I call everybody mate or man or dude, of course I wouldn't go to a job interview and say "mate" but as this is a Internet forum I didn't think I needed to call you his lordship......
I speak English extremely well funny enough but writing is another story, you do realise you come across so snobby and pretentious when you speak to people this is part of the reason you irritate many people Michael. You have a "common" accent so you must get judged a lot on yours then?
I have never corresponded with anyone on the Internet and referred to them as mate, man or dude. Neither would I use such language in person to anyone. That is the way I am and was raised. I do not use profanity when talking to people either. Where I live I have never heard any of my neighbours use expletives during conversation. When conversing with members of my family it is the same.
I was born and bred in London and now live in Brighton. I am a carpenter and Joiner but now retired. I have worked with men that use swear words during conversation, something which is common among some people in the building trade. However, those that I have associated with over the years, soon stopped swearing when they realize I don't join in with them. I just carry on as if nothing has happened. Some that I have worked with, asked why I don't swear. I just say my parents brought me up not to. It is something totally unnecessary to use during normal conversation. A person that frequently uses profanity needs to be careful, as they might find themselves around certain people that don't use that type of language and embarrass themselves.
Although I am was born and bred in London, I assure you I do not have a cockney or typical London accent. My late Mother and Father would be most displeased if they heard me speaking that way....lol.
I wish you well.
Michael
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