We should then be able to determine whether this also (to quote Lenin) belongs in "The Dustbin of History" (along with AM-101, Neuromonics, SoundCure, Desyncra, Lenire, Lipoflavonoid, etc.).
What do you expect one watered-down-for-laymen's-consumption presser to tell you, that you couldn't learn in much more detail from reading their considerable body of published whitepapers and preprints?
How will one single interview tell you whether a technology belongs in the "dustbin of history" when it's still at least a couple years away from being ready for consumer adoption?
I totally understand impatience and skepticism, but some of the doomerism around here is ridiculous to me.
Anyone who wants to know the current status of this research, whether COVID-19 has impacted their trajectory, and what they see as their current target window for a potential launch should just email them; I've had nothing but good interactions with that lab over the past few years. Most of my emails to Dr. Shore ended up getting deflected to PhDs and research assistants, but, if I was a tenured professor working on a tinnitus thing, I would no doubt do the same...
I can totally get how a negative outcome could come out of such a device. I would have thought that a stimulation device using sound seems like something that might make tinnitus worse.
The sound itself is actually not the problem, at all -- we're rewiring the brain here, kiddos, and making the impossible possible. (The idea of eliciting structural brain changes using noninvasive bimodal stimulation to exploit spike-timing dependent plasticity in a very specific way would have been pure science fiction 20 years ago).
I've been impressed with the normal research-institution patience and safety protocols UMich has used, including publishing basically all their data in a pretty expedient way.
Lenire is a venture capital backed for-profit enterprise. They have a very different set of constraints, goals and resources than a research university, and I inherently distrust that world because I have worked in it a lot. Additionally, they are selling a device in Ireland based on an approval that was granted for a
different, earlier device, and they haven't remotely cleared the approval hurdles in the US.
I think these things should make us deeply suspicious of Lenire. At the same time, if we're messing around with DCN wiring, and one of the companies doing it is a VC-backed place doing a halfass job publishing their data.... well, I'd more or less
expect some amount of adverse outcomes?
That is, if someone got trigeminal neuralgia from this, that's awful, and if that would have been avoidable with safer / better research on behalf of Lenire then it sounds criminal. But, that's only
possible if this technology is, in general, doing what it claims to: rewiring the brain at the DCN level.