Steroids: Prednisone / Dexamethasone / Others (Oral and Intratympanic Injections)

[Liam_Cairns]

Yeah mine is in the UHF, but I have no hearing loss I can hear up to 19 k at 5db and have been retested twice, man tinnitus really works in mysterious ways. But yeah if you have any more question seriously hmu just cause I would hate to see you get a worsening from something like that

 

[Danton]

Yeah mine is in the UHF, but I have no hearing loss I can hear up to 19 k at 5db and have been retested twice, man tinnitus really works in mysterious ways. But yeah if you have any more question seriously hmu just cause I would hate to see you get a worsening from something like that

Hey liam, I live in the brisbane area and was wondering which clinic had that quiet MRI, I've been having funny feelings in my left hip 4 weeks after doing a week course + taper predniosone 6 days after noise exposure, I was doing insanely well until, 3 days ago where I went to a moderalty loud party with ear protection, and woke up with a raging buzz, I got scared and it didn't really improve this morning so in my weakness I took a 64mg dose of prednoisone, I realize that was a mistake, How high of a dose did you take that you stopped cold turkey from?, Does anyone know if I should take 30 tomorrow, then 14 to taper off or just stop cold turkey, Need help.

 

[Liam_Cairns]

Hey liam, I live in the brisbane area and was wondering which clinic had that quiet MRI, I've been having funny feelings in my left hip 4 weeks after doing a week course + taper predniosone 6 days after noise exposure, I was doing insanely well until, 3 days ago where I went to a moderalty loud party with ear protection, and woke up with a raging buzz, I got scared and it didn't really improve this morning so in my weakness I took a 64mg dose of prednoisone, I realize that was a mistake, How high of a dose did you take that you stopped cold turkey from?, Does anyone know if I should take 30 tomorrow, then 14 to taper off or just stop cold turkey, Need help.

Hey Danton it is at the QE2 Hospital QLD Xray department. It is a private machine tho, so even with Medicare you get nothing back unless you have ever been an inpatient at QE2.

Oh and I would personally not take anymore in your position.

 

[Arseny]

Yeah, muscle loss is common, especially with fluorinated steroids such as dexamethasone, did you get steroids for your hearing loss, or something unrelated? As I have never really heard of oral dexamethasone being used for tinnitus.

I had intramuscular injections.
I had first course after a spike due to MRI, I think it helped a bit.
Other two were combination of spikes due to noise exposure and allergies, mostly allergies. Thankfully I feel better now.

 

[racerfish]

Hey liam, I live in the brisbane area and was wondering which clinic had that quiet MRI, I've been having funny feelings in my left hip 4 weeks after doing a week course + taper predniosone 6 days after noise exposure, I was doing insanely well until, 3 days ago where I went to a moderalty loud party with ear protection, and woke up with a raging buzz, I got scared and it didn't really improve this morning so in my weakness I took a 64mg dose of prednoisone, I realize that was a mistake, How high of a dose did you take that you stopped cold turkey from?, Does anyone know if I should take 30 tomorrow, then 14 to taper off or just stop cold turkey, Need help.

What happened when you took the 64 mg dose?

 

[JohnAdams]

Apparently you can get it after subsequent acoustic traumas while you are still in the acute stage.

 

[Marko Nakovski]

@Arseny Can you take those kinds of steroids only in the beginning stage of hyperacusis or isn't the timeframe of one's onset important? If so, the same applies for HBOT?

 

[Liam_Cairns]

Apparently you can get it after subsequent acoustic traumas while you are still in the acute stage.

You got a source for this?

 

[JohnAdams]

You got a source for this?

An ENT told me.

 

[JohnAdams]

You got a source for this?

Also, that would make sense, new damage is acute in nature. Dexamethasone is proven to help in the acute stage.

 

[Liam_Cairns]

Also, that would make sense, new damage is acute in nature. Dexamethasone is proven to help in the acute stage.

Wait hold up sorry I misread your comment, when you say "you can get it" do you mean hyperacusis?

 

[Danton]

What happened when you took the 64 mg dose?

I got pain in all through my legs, then a new one on my right hip, Unfournatly the hip pain continued after I stopped, now both my hips have pain in the sockets and I'm deathly afraid I got AVN (Necrosis) all I can do keep weight off the joints and see the doctor.

 

[JohnAdams]

Wait hold up sorry I misread your comment, when you say "you can get it" do you mean hyperacusis?

do they not give it at ENTs?

 

[Liam_Cairns]

do they not give it at ENTs?

Intratympanic injections of Dex but oral is normally Pred.

 

[JohnAdams]

Why isn't everyone in the acute stage of noise induced hearing loss being given Dexamethasone injections??????????

 

[Marko Nakovski]

@JohnAdams What's the timeframe for acute stage? Is it 3 months or 6 months? I want to try it in order to improve my hyperacusis ...

 

[dpdx]

@JohnAdams What's the timeframe for acute stage? Is it 3 months or 6 months? I want to try it in order to improve my hyperacusis ...

how many months have you had severe h?

 

[Marko Nakovski]

@dpdx In general I have hyperacusis for 3 months and 1 week. My first 3 weeks were very severe, next 1 week little improvement, something like between severe and moderate, next 2 and a half weeks moderate then some setback (I don't know the cause, maybe car horns) and worsening, then after new year very severe for the past month, especially in the last 2 weeks. I would like to try these steroids.

 

[dpdx]

@dpdx In general I have hyperacusis for 3 months and 1 week. My first 3 weeks were very severe, next 1 week little improvement, something like between severe and moderate, next 2 and a half weeks moderate then some setback (I don't know the cause, maybe car horns) and worsening, then after new year very severe for the past month, especially in the last 2 weeks. I would like to try these steroids.

Do you have sound sensitivity or ear pain/burning?

 

[Arseny]

@Arseny Can you take those kinds of steroids only in the beginning stage of hyperacusis or isn't the timeframe of one's onset important? If so, the same applies for HBOT?

I think the time frame is very limited:
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4664349/

It would make sense to go for steroid treatment if you have recent injury. Otherwise it might be not worth it.

I would attribute my progress more to HBOT than to steroids.

You can try one or two injections and see if it makes any difference. At that point you can stop cold turkey.

 

[dpdx]

@dpdx In general I have hyperacusis for 3 months and 1 week. My first 3 weeks were very severe, next 1 week little improvement, something like between severe and moderate, next 2 and a half weeks moderate then some setback (I don't know the cause, maybe car horns) and worsening, then after new year very severe for the past month, especially in the last 2 weeks. I would like to try these steroids.

Is your tinnitus severe as well?

 

[Eric N]

I had intramuscular injections.
I had first course after a spike due to MRI, I think it helped a bit.
Other two were combination of spikes due to noise exposure and allergies, mostly allergies. Thankfully I feel better now.

Do you still have the spike from the MRI?

 

[GSC]

So, what is the actual time window of taking Dexamethasone injections into the ear. Does anyone know, I know the sooner, the better, but still.

 

[Jack Straw]

Hey I just thought I should share my experience with prednisone as a cautionary tale,

I took a course of prednisone for an acoustic trauma back in May and it left me crippled for a few months. It wasted all the muscle in my legs, I could barely walk without experiencing violent cramping and have only now just gotten back to being able to run after months of rehab.

While I truly believe this drug can help with some people's tinnitus, I think people need to be incredibly cautious about weighing up the risks, especially since this can cause vascular necrosis even after short-term treatment, which is truly awful.

@Ed209 you will find this interesting.

 

[Mark Foster]

Guys what is your experience with corticosteroid intratympanic injection?
I had noise induced tinnitus for 2 months and I wanted to get an ear injection done, but I've visited 2 doctors already and they said it's not proven to work. Should I keep trying new doctors or should I just surrender?

 

[GSC]

Guys what is your experience with corticosteroid intratympanic injection?
I had noise induced tinnitus for 2 months and I wanted to get an ear injection done, but I've visited 2 doctors already and they said it's not proven to work. Should I keep trying new doctors or should I just surrender?

It's already too late. They will only do an injection if there's an obvious dip in your audiogram.

 

[Mark Foster]

There is a dip at 4.2 kHz and 8 kHz, but like -30 dB, nothing deadly, but my tinnitus is loooouuud.
From the research I've read an injection could "possibly" help my case as well.

 

[GSC]

There is a dip at 4.2 kHz and 8 kHz, but like -30 dB, nothing deadly, but my tinnitus is loooouuud.
From the research I've read an injection could "possibly" help my case as well.

You have until month three for effectiveness and the possibility of it helping your case. If you want to keep going this route, you can keep trying, but it will be very hard to find an ENT who will do this. Maybe print out proof on how much it helps and research that it does in order to make your case known if you are going to see another ENT.

 

[Mark Foster]

You have until month three for effectiveness and the possibility of it helping your case. If you want to keep going this route, you can keep trying, but it will be very hard to find an ENT who will do this. Maybe print out proof on how much it helps and research that it does in order to make your case known if you are going to see another ENT.

I have finally found a doctor who accepted to try it (costs quite a bit), I think I'll go in next week, but he suggested for one ear only.

 

[bendaver]

I was diagnosed 3/28/2019 with SSNHL. It was caused by several viral infections from late Fall 2018 through Winter and early Spring 2019. I never really (100%) was able to escape the virus ... somewhat my fault for not persisting with my primary care physician to continue hitting it with another round of med.

So, I contacted my ENT. A full exam of my outer-to-middle ear revealed nothing alarming, but the follow up (audiologist in that office) the same appointment revealed that I had 100% hearing loss in my left ear.

So my ENT prescribed a round of prednisone. After completing it, I went back to my ENT, to report I had no change in my hearing, and I had continued (as before) to have extreme vertigo and tinnitus. An appointment was made right away by my ENT to meet with an inner ear specialist a few days later.

The specialist agreed that I had SSNHL and he recommended, then and there, to begin intratympanic (into/through the ear drum) injections of Dexamethasone. Three injections were administered over a 9-day period. The physician said that, even though I sense no change to date (now 1-week after the final treatment, that he has seen down the road benefit. So, there may yet be hope.

Meanwhile, I do daily exercises that he gave me to do at home to deal with my vertigo. I have improved a bit, in that regard. But my tinnitus has worsened and it's seems to change in intensity and variability. I have a constant seashell/white noise that is quite loud and it is with me 24/7. In the last couple of days, a new sound overlays that seashell sound, which us a repetitive hum (like a fog horn) that repeats every 3-5 seconds in 1-second long bursts ... it is quite annoying. I keep myself busy throughout the day, occasionally listening to books on Audible. In the evening I listen to quiet nocturnes (Debussy or Chopin) to lull me into sleep.

This entire day-to-day experience drives me crazy, but I try not to let it get me down .. keeping busy helps; fortunately, I am retired and I have a quiet house while my wife is at work. I hope this ends soon ... that I see some relief. I know that my vertigo will eventually come under control with exercises, and I hope that eventually I become accustomed to the tinnitus, but I am concerned about my unilateral deafness.

I read all day long about options ... technical fixes to address my deafness. Cochlear fixes, such as titanium cranial implants (Osseointegration) offer some hope, but I am hesitant to agree to any workaround that may have long-term side affects. I need to do more reading, talk further with my otolaryngologist, and perhaps reach out to other professionals to understand all if the options available to me.

Hopefully this forum will provide me with some solace ... millions of people struggle with this illness ... I'd like to know about the various coping mechanisms that others use to make the adjustments a livable, sustainable quality of life. Thanks to this community for any input.