University of Minnesota Tinnitus Research with Acoustic and Body Stimulation

[hans799]

Neural networks? That would be quite interesting, but I'm unsure about how it would work with so few samples. Do you have a source?

I mentioned neural networks in the sense that Dr Shore models the brain parts responsible for tinnitus as a feedforward neural network, and uses this model to arrive at the correct timings. So to replicate the timings we'd need to come up with a similar model, which would require serious neural networks expertise.

But in this case we're talking about a literal network of living neurons, not neural networks in the machine learning sense (although that would surely be cool).

For example, see this study: https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2566901/

 

[GregCA]

But in this case we're talking about a literal network of living neurons, not neural networks in the machine learning sense (although that would surely be cool).

Ah ok, thanks for clarifying! I thought you meant in the machine learning sense, and that triggered my curiosity!

 

[Paulmanlike]

Just let the woman do it for you, don't build machines, leave it to the expert Susan Shore.

 

[SuntoryTime]

That's amazing you know how long it's going to take this drug to be released. Do you have a source for that or are you just guessing based on averages?

That's an educated guess. Large scale Phase III trials tend to take years, realistically 3 to 5. The Shore device will arrive before FTX's more complex technology because it has been in the clinical trial pipeline longer. I'd be delighted to be wrong about this and have both technologies available sooner. But I guess I can wait a little longer. I am now surviving on sheer force of will.

 

[MadsWithT]

How do you figure that?

By evaluating the various possible treatments from a layman's perspective. Hence, my opinion is subjective. I'll certainly respect other opinions but I won't go into a long chain of arguments on the merits of the range of different venues being explored in order to cure tinnitus. I understand that you are in favor of some drug. If that drug turns out to cure the ailment, I would be very happy. However this thread concerns the bi-Modal avenue. I would be very happy if that works. That's how I figure things.

 

[JohnAdams]

By evaluating the various possible treatments from a layman's perspective. Hence, my opinion is subjective. I'll certainly respect other opinions but I won't go into a long chain of arguments on the merits of the range of different venues being explored in order to cure tinnitus. I understand that you are in favor of some drug. If that drug turns out to cure the ailment, I would be very happy. However this thread concerns the bi-Modal avenue. I would be very happy if that works. That's how I figure things.

I highly recommend you look into this some drug.

 

[MadsWithT]

I highly recommend you look into this some drug.

Sure.

 

[Paulmanlike]

http://soniclab.umn.edu/research/neural-beamforming-tinnitus

Apologies if this has been uploaded, was just researching University of Michigan website and came across it.

 

[Rafahyperacusis]

Do you think this is gonna work for people who has H too @kelpiemsp ?

 

[PDodge]

When is this trial supposed to end?

 

[Don Tinny]

Perhaps it was already asked before. Are Minnesota's trials for somatic tinnitus? or are they more similar to Neuromod's?

 

[spedgas]

I have no idea where they are in the process. Does anybody have any idea where the University of Minnesota is in the process and what their expected end date is?

I'm also wondering if there will be any issues with Hubert Lim being poached by Neuromod. How involved was he at the University of Minnesota?

 

[kelpiemsp]

Do you think this is gonna work for people who has H too @kelpiemsp ?

Just last night my wife said "wow your tinnitus must be better" I said "why's that?" She replied...well a balloon popped and you didn't run out of the room. I paused and was like...huh. So yes, it really does. I was sensitive to all sound above 60 db for quite some time.

Perhaps it was already asked before. Are Minnesota's trials for somatic tinnitus? or are they more similar to Neuromod's?

All signal timing is the same, it IS using a somatic pathway. Will have to wait for more information.

When is this trial supposed to end?

December 31st, 2018

I have no idea where they are in the process. Does anybody have any idea where the University of Minnesota is in the process and what their expected end date is?

I'm also wondering if there will be any issues with Hubert Lim being poached by Neuromod. How involved was he at the University of Minnesota?

I'm super curious about this. I think Lim is still running this trial. If I had to guess, he will be in both spaces. It makes sense from Neuromods point of view. Neuromod probably brought on Lim to acquire IP from the trial at the UofM.

 

[parsky]

Just last night my wife said "wow your tinnitus must be better" I said "why's that?" She replied...well a balloon popped and you didn't run out of the room. I paused and was like...huh. So yes, it really does. I was sensitive to all sound above 60 db for quite some time.

This is pretty cool. Hopefully the only side effect is increased happiness!

 

[PDodge]

Thanks! @kelpiemsp

 

[Johan_L]

Just last night my wife said "wow your tinnitus must be better" I said "why's that?" She replied...well a balloon popped and you didn't run out of the room. I paused and was like...huh. So yes, it really does. I was sensitive to all sound above 60 db for quite some time.



December 31st, 2018

So... Your sensitivity to sound improved? Did/do you have H?

Also.. December 31st was yesterday! Is the trial over now?

 

[duder12]

I finished the trial but we have not gotten a final report that I am aware of. I have tinnitus/high frequency hearing loss in both ears and can modulate it with my jaw.

My personal opinion is that it did nothing for me.

My tinnitus was fairly new before my treatment though so I was getting used to it as the trial went on. I'm going to try and see if it gets worse now that the trial is done but I'm guessing it will be the same.

 

[MadsWithT]

I finished the trial but we have not gotten a final report that I am aware of. I have tinnitus/high frequency hearing loss in both ears and can modulate it with my jaw.

My personal opinion is that it did nothing for me.

My tinnitus was fairly new before my treatment though so I was getting used to it as the trial went on. I'm going to try and see if it gets worse now that the trial is done but I'm guessing it will be the same.

Say, you write that Meniere's decease is your cause of tinnitus. I mean to recall that that particular cause was a exclusion point form these trials? Or am I wrong?

 

[Don Tinny]

I finished the trial but we have not gotten a final report that I am aware of. I have tinnitus/high frequency hearing loss in both ears and can modulate it with my jaw.

My personal opinion is that it did nothing for me.

My tinnitus was fairly new before my treatment though so I was getting used to it as the trial went on. I'm going to try and see if it gets worse now that the trial is done but I'm guessing it will be the same.

It sounds pretty hopeless. It is assumed that these devices (Minnesota and Michigan) are more effective than the MuteButton.

 

[Bill_]

It sounds pretty hopeless. It is assumed that these devices (Minnesota and Michigan) are more effective than the MuteButton.

Considering that his tinnitus was caused by Mèniere's I wouldn't throw my hopes out of the window just yet. Mèniere's might very well be a rather "special" case.

 

[Manny]

@kelpiemsp per your status you now have silence?? Wow!! May I please hear more?

 

[hans799]

Wow! Looking forward to his reply

T is behaving badly this evening. A dose of hope is nice.

 

[Jack Straw]

 

[Jack Straw]

@kelpiemsp per your status you now have silence?? Wow!! May I please hear more?

Start the hype train for biomodal stimulation?

 

[Manny]

Start the hype train for biomodal stimulation?

How can I rate a post "hug" and "good question" at the same time?

 

[hans799]

Start the hype train for biomodal stimulation?

Well, with @Clare B and @kelpiemsp both reporting silence from various bimodal treatments, plus an encouraging study from Dr Shore last January and even more encouraging preliminary results from Neuromod in the Q&A, the hype train is starting to move I think

 

[Jack Straw]

How can I rate a post "hug" and "good question" at the same time?

Haha looks like we'll be getting drinks sooner than I thought!

I know this isn't neuromod but it proves for a FACT that this type of technology works from a legit forum member. Great news today everyone!

 

[Jack Straw]

 

[hans799]

I know this isn't neuromod but it proves for a FACT that this type of technology works from a legit forum member. Great news today everyone!

If you look, it was actually @kelpiemsp who started this thread and brought Minnesota to our attention. He pulled himself up by his own bootstraps.

 

[EDDTEKK]

Why he doesn't share such experience in this thread we need some hope and success stories.