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Regeneron gene therapy restores hearing in deaf child Regeneron’s gene therapy for otoferlin-related hearing loss – a genetic cause of deafness – has restored hearing to normal levels in one profoundly deaf child within just 24 weeks. The result comes from a phase 1/2 study of the company’s...

Elon Musk: ‘Mark my words — A.I. is far more dangerous than nukes’ Also Elon Musk: ‘ultimately the goal is to achieve symbiosis with artificial intelligence’ :D

> For anyone curious about the accuracy of the #WatchOS6 Noise app, here’s a comparison with a decibel meter this morning.

The new Apple watch has a native decibel meter. I’m happy to see it will bring some conscience about hearing loss. No one told me back in the time! From what I’ve read on the web, the phone decibel meters are quite accurate. I carry one on my iPhone...

I have the same experience. I wake up after 90 min. I used to worry silly about it, or start thinking about stuff for hours. Now I don’t engage in worrying thoughts and go back to sleep. Yes, I have T, it is a nuisance, but I still intend to sleep as much as I can. Meditating (with Headspace)...

I’m skeptic. Acupuncture has no physiological base and its efficacy has not been proven in any meta-study. 19 out of 30 cases were cured. It comes from China, specifically from a “Hospital of Traditional Chinese Medicine”.

The paper says that you will reinforce tinnitus if you play white noise, even when it is initially distracting. The theory is that white noise reinforce cells that generate the perception of noise, and vice versa, you are better off listening to music and speech, specially if they have been...

Nature sounds from Spotify, for instance there is a bit of everything in there, you have to find your own, Spotify has everything. It may take a while to habituate to some of that. A friend went to work in the jungle, and it was mayhem at night, she habituated to that. You can also get used to...

Someone posted a screenshot of this question: What is the mechanism behind tinnitus? Here is the link: https://biology.stackexchange.com/questions/30229/what-is-the-mechanism-behind-tinnitus It enumerates six theories explaining the origin of tinnitus.

If anyone is curious (I was!) a voice through a cochlear implant sounds like this. I read something elsewhere about researches trying to improve the quality of the sound. Not looking forward to have my brain drilled, but I wonder if this could restore hearing one day.

Quoted from How can I convince graduate students in China to not copy/paste from the Internet into their research papers?

This kid was born without a cochlear nerve. He is the first to get his hearing restored by receiving an implant that bypasses the nerves and connects directly to his brain. This was a trial of the Food and Drug Administration. Click here to see a picture of the stem implant in ABC News...

[x] not sure, but around the time we get flying cars, more or less. :D

Well, I would be dead already. Same as when I light a match and the sulfur ignites at 230C. Do I melt? nope. Clapping as hard as I could, the db meter in my phone registered 86db. Far from the Guinness world record, which is 113 dBA...

Indeed :) and I have read similar comments in this forum. The first time I heard T, I went through my room trying to locate the sound. When I finally found it... are you serious life?? I take consolation knowing that others are struggling in the same fight. @SomaticT I have bruxism and a mouth...

Custom made plugs. They spray your ears with foam, it hardens, they take it out, and make a mold. From that, they create transparent small earplugs. I got several kinds, but what worked best for me are those made from a solid chunk of transparent flexible plastic (no fancy filters or anything...

I usually sleep for a REM cycle (around 2 hours), wake up, check the clock, continue sleeping. But sometimes I wake up to the tune of new tinnitus patterns, continuous beeeeeeep, or repetitive machine-like noises. What's curious is that if I wake myself up it fades, and if I wake myself up...

90 mins sounds like a REM cycle. It’s not uncommon to wake up for a few seconds, then go back to sleep and not even remember it happened.

@EDDTEKK click the name of an user, then click on start a conversation.

It’s simple Sandra, in 10 years, we will have the technology to turn people into mice. At that point we will be able to fix their hearing. Then the problem is reduced to turn the mice back into people.

The beep went away after a few hours I think. Still anxious about the spike but manageable. Mysteries of Tinnitus I guess.

It is a recurring theme that you start thinking life is over because you obsess over your background noise. It is like living next to a road when you used to live in the country. You do get used to the background sound. I still get anxious at times, but my situation is a lot better than before...

Suddenly I heard a beep anytime there is a loud noise, for instance, flushing the toilet triggers it. What is this? It started half an hour ago. I was playing a shooter online which gets me stressed, and noticed tinnitus being the loudest it has ever been. I got scared, and noticed a beep in...

It doesn't work like that. Small animals are usually given high doses of drugs to see if anything interesting happens. They disregard side effects which may be severe. These are preclinical trials. From https://en.wikipedia.org/wiki/Phases_of_clinical_research That is safe.

The link above is 404 so here are a few more links about it: http://hearinglosshelp.com/blog/do-i-have-tonic-tensor-tympani-syndrome-ttts/ http://www.noiseandhealth.org/article.asp?issn=1463-1741;year=2013;volume=15;issue=63;spage=117;epage=128;aulast=Westcott...

This picture represents over 30 years of progress in video game graphics. On the left, Indiana Jones in the video game version of Raiders of the Lost Ark on the Atari 2600. On the right, Nathan Drake in Uncharted 4 on the PS4. Who would have thought? Like with weather, predictions beyond the...

Just googled this: http://www.canadapharmacyonline.com/DrugInfo.aspx?name=Potiga6804

Did you deviate from normal sleep patterns?, did you drink alcohol?, were you anxious about being on a club at 100db? I went out too, plugged of course, but the sum of all that, plus the exposition to 95-105db may have been the cause of increased Tinnitus. It's hard to say. Probably the sound...

Hi all, I wanted to share with you the following email I got today from Peter Phua of AudioNotch. I liked it myself, hope you do too. From: Dr. Peter Phua of AudioNotch.com Why hope? It’s a simple question. Despite the best efforts of medical science, and despite the existence of...

It is, at least, not blatantly stupid. Space research is the olympics of science, it's inspiring, and it has produced scientific advances commonly used today. To put humans on mars is out of reach, but to send a robot there it's as costly as a blockbuster movie and quite a feat of engineering...

@Sean @Carlos1 Me too! :)

In Vivo Activation of a Conserved MicroRNA Program Induces Mammalian Heart Regeneration http://www.cell.com/cell-stem-cell/abstract/S1934-5909(14)00454-8 Heart failure is a leading cause of mortality and morbidity in the developed world, partly because mammals lack the ability to regenerate...

Ankylosing spondylitis. Started at 19, stopped at 38 (no symptoms).

First they put a small foam plug attached to a cord that they press gently inside your ear. That blocks the sillicone from entering the ear canal. Then they push the sillicone inside your ear. The sillicone is a soft material, it was like someone spraying my ear with shaving cream. The sillicone...

I had the same concern, but the product that gets into your ears is very soft, you feel no pressure at all. It felt safe. The custom ear plugs are waaaay easier to wear than the foam plugs.

Sometimes you need a quiet environment to focus on really challenging work. The humming of the air conditioner or the multiple computers in the room are enough to mask most Ts. Unfortunately some companies are unaware of the inner workings of the human mind or think we are just there for grunt...

After 18 years of follow-up, 5,289 incident cases of tinnitus were reported, showing a significant inverse association between the amount of caffeine intake and the incidence of tinnitus. The cause is unknown...

A few newspapers carry the following news: For example http://www.independent.co.uk/news/science/stem-cell-trial-cures-blindness-for-many-patients--and-with-no-side-effects-9794301.html http://www.theguardian.com/science/2014/oct/15/stem-cell-success-in-treating-macular-degeneration While...

After 18 years of follow-up, 5,289 incident cases of tinnitus were reported, showing a significant inverse association between the amount of caffeine intake and the incidence of tinnitus. The cause is unknown...

No, I haven't. But I have had unrelated procedures and drugs that many people here are scared of. Everything carries a risk, but the point of statistical analysis is that 1:1000 chance of a bad reaction is worth it. I know it's comforting to talk to a sufferer here, and that you consider...

Last time I made a MRI there was a patient yelling "get me out of here". I guess he was claustrophobic. MRI induces a lot of anxiety, one reason being the chance of worsening due to noise. In general, if a doctor tells you to do something, the risk is worth the reward. Don't confuse someone...

I find that a full restaurant is 85-90, rarely 95. Custom plugs with a 15db filter are enough to feel safe. People find it natural that I wear them. They never ask about it. I guess they think I'm hear impaired or something.

I wake up after 3 hours, check the clock.. oh shit, only 3 hours?... then go back to sleep and wake up a couple more times. Sometimes it takes an hour to sleep again, sometimes 5 minutes. I have bruxism but I don't consider that related. Little known fact: those with a particular variant of the...

This has been my experience too. 5 years now and getting worse very slowly. A week ago I was exposed to 85-95 dB during Apple keynote and now I have a faint nightly morse code added to my orchestra. I don't know even know if that was the cause. I plug a lot but just to decrease the level 15dB...

I was a bit worried about filling my ears with that stuff (silicone? I don't know), and the chance of blowing up my eardrum in the process. However, the filling up is very very gentle, feels harmless, and the whole thing comes out easily and totally. I got a pair of earplugs with a filter. They...

I use these ear plugs: http://www.amazon.co.uk/dp/B0026IR2SM/?tag=tinntalk-21 I also have the expensive custom made ones, which are definitely more comfortable and easy to plug, but in decibel reduction, those “MAX” are as good as it gets (my subjective opinion). My T is also worsening. I'm on...

No, haha, just a fan. I'm not famous but I show up on google search easily enough, and I don't want any potential disability associated with me in case it harms my chance of employment.

Try outdoor activities. Swimming, trekking, weight lifting are fine to do with T. Check meetup.com.

Speaking of what, I saw them (arcade fire) in the primavera sound festival in barcelona. Great show. I went friday and saturday plugged and it wasn't too loud.

The musician plugs are usually 9 or 15 or 25. They have a filter to let the conversation through and block low frequencies. I tried them on the noisy subway of London and they make a difference, I no longer worry about the screeching rails.

When the manufacturer advertise that they are the best in the market, who is there to say otherwise? I wear the Leight MAX 1 which advertise 37. They are good, but I'm not convinced about those numbers.

After a few days it seems the earplugs do their job. Traveling in the subway is no longer so annoying. Some London stations really are very very loud. The earplugs attenuate some frequencies and let the rest go through. They are very comfortable.

Yes, it drops for one second, that's fleeting tinnitus too, someone called it “oscillation secondary to instability in the nonlinear electromechanical properties of the outer hair cells, with a rapid stabilization with a dampening of oscillation” (LePage, 1995). I have no idea what that means.

Don't worry. The drilling should be painless and low noise. The jawbone has lower density than the teeth so the drilling is a lot less noisy and they also have to stop to let the bone cool down and not hurt any nerves. When a wisdom tooth is pulled, they should put some growth factor in the hole...

If you have bruxism you should wear a retainer to protect your teeth and more importantly, the temporomandibular joint. Bruxism may be stress related and disappear, come and go, or be constant. I got a retainer at the dentist, it's easy to do. Sometimes it takes a hmm don't know the word in...

Got my Elacin ER Flexcomfort-whatever earplugs and they attenuate too little. They are very soft and comfortable but it's almost like having nothing on. They told me a reduction of 25db would be too much so I aimed for 15db. When I plug these cheap Howard Leight MAX-1...

Because it draws your attention to the experience. When 5.1 sound came up, I saw a demo at the mall. They were playing Cliffhanger (1993) so loud I could feel my internal organs vibrating. Awesome! I had a friend whose ears ring after concerts. I tried to warn her but she won't listen. :( I...

I challenge your reign as queen of the smallest ear canals! dude told me my impressions were so small they could cause problems in the earplug factory. I will know in a few days. Anyway, having small ear canals doesn't have a clinical significance.

Is it just me or this is a huge breakthrough?

Judgement values are a way to promote change by inflicting guilt. However, they are not effective, because our victim is more likely to deviate her energies in self defense, counterattack, and feel low self-esteem because of it. They don't foster understanding either, because a label simplifies...